As a site proposed for testing vaccines in humans, we requested and were given approval for evaluating
different vaccine candidates for safety and effectiveness.
Vaccine research will also benefit immediately from the discovery, since scientists can already now test the effectiveness of
different vaccine candidates at preventing PfEMP1 from binding ECPR.
In a previously published paper, Barouch and colleagues, including Colonel Nelson L. Michael, MD, PhD, director of the Military HIV Research Program at the Walter Reed Army Institute of Research (WRAIR) and Stephen Thomas, MD, Upstate Medical University, State University of New York, demonstrated that three
different vaccine candidates provided robust protection against Zika virus in both mice and rhesus monkeys.
Not exact matches
At Penn, two
different Zika
vaccine candidates are in various stages of development.
In case it takes a
different course, the CDC asked the laboratory that makes
candidate vaccine viruses to make one for the swine H3N2.
The cholera studies led to the scuttling of a leading
vaccine candidate, a finer understanding of effective immune responses, and, ultimately, compelling evidence that a
different cholera
vaccine worked.
When injected into rabbits, the
vaccine candidate stimulated antibody responses against the sugar shield in four
different HIV strains.
The Fraunhofer IME leads the Transnational Access 1 (TNA1) «Cross platform screening and optimization service «and the corresponding Joint Research Activity (JRA1) «Improved optimization and harmonization of cross-vector screening «both aiming at the provision of comprehensive range of
different well established pro- and eukaryotic expression / production systems to identify the optimal manufacturing platform for any given
vaccine candidate.
This service will allow users to improve the compatibility and stability of their
vaccine antigen with
different mucosal adjuvants (from the HZI portfolio) and to define the optimal production methods to generate immunogenic
vaccine candidates with optimised physicochemical stability (in vitro studies).
The Transnational Access 1 (TNA1) «Cross platform screening and optimization service «and the corresponding Joint Research Activity (JRA1) «Improved optimization and harmonization of cross-vector screening «will combine the expertise of six
different partners (IME, SSI, UOXF, iBET, BPRC and UNISI) to provide the unique offer to test
vaccine candidates in a comprehensive range of
different expression hosts, to identify the optimal production system for further pre-clinical and clinical development.
The integrated production platform aims to produce and purify these proteins using a combination of engineered microbial cell factories and flexible approaches for purification to accommodate
different vaccines and future
candidates.
Although the specific function of the
different merozoite surface proteins (MSPs) remains elusive, MSP - 1 and MSP - 3 are currently under evaluation as
vaccine candidates.
Since 1987, there have been over eighty trials of thirty
different candidate AIDS
vaccines.