This means it might be necessary to develop several
different vaccine strains to ensure one provoked sufficient response.
Not exact matches
We can not develop a
vaccine for AIDS because its structure changes so rapidly, oftentimes from host to host the
strain is
different.
«There were a couple of these in the
vaccine strain the past two seasons that wound up making it a little bit
different from the actual circulating virus
strain.»
Orme and his research team in Fort Collins investigated whether the existing
vaccine for TB, which goes by the acronym BCG (bacille Calmette - Guerin), worked equally well against
different clinical
strains of tuberculosis.
In the coming months, scientists will have to evaluate the trial's full data to determine why the
vaccine failed: Were the infecting viruses too
different from the
vaccine strain to offer resistance?
«The high diversity found within the [TcI]
strain may challenge
vaccine development and treatment improvement, if the genetically
different strains respond differently to particular medication.»
«For instance, diagnostic tests could be tailored to
different strains or stages of the disease,» and
vaccines could be designed to skirt interaction with the human body.
Eventually the
vaccine will contain a cocktail of proteins mimicking up to twenty
different strains of the virus from around the world.
The
vaccine was targeted especially toward the virus
strain circulating in Thailand, and it may not show the same effectiveness where the virus is
different, such as Africa or the U.S. And even the 31.2 percent fewer cases that it resulted in is hardly an ideal preventative strategy.
Teijaro adds that the ideal approach may be to combine the HIS virus
vaccine with a strategy to generate broadly neutralizing antibodies — those that can bind many
different influenza
strains — to create a universal flu
vaccine (SN: 10/28/17, p. 18).
Strep
vaccine groomed new superbug Prevnar, a
vaccine given since 2000 to prevent potentially fatal childhood infections caused by seven
different strep
strains, may have opened the door for a new variety of the bacterium that shrugs off all pediatric antibiotics.
Significantly, J&J's latest
vaccine uses so - called mosaic technology to combine immune - stimulating proteins from
different HIV
strains, representing
different types of virus from around the world, which should produce a «global»
vaccine.
A second HPV
vaccine, Cervarix, which is made by GSK and targets some
different HPV
strains, is still in review by the FDA.
When injected into rabbits, the
vaccine candidate stimulated antibody responses against the sugar shield in four
different HIV
strains.
However, eosinophil scores were significantly
different between groups (p < 0.001, Anova) with significantly lower scores for nonvaccine groups than for
vaccine groups of both mouse
strains (p < 0.001 for all comparable group comparisons, Tukey's HSD).
Photomicrographs of the
different vaccine and mouse
strain groups are shown in figure 9.
GMT for the BPV
vaccine and live virus were not
different for the two
strains p >.05.
One application of sieve analysis, once it's learned that a
vaccine's efficacy depends on the genetics of the pathogen, is for the
vaccine manufacturer to add a
different strain or
strains to the
vaccine to increase its protectiveness.
«Influenza yearly protection is important for preventing the flu,» said Spicehandler, who is co-chief of infectious diseases at Northern Westchester Hospital in Mount Kisco, N.Y. «Each year the
vaccine is made up of
different strains to protect against what viruses are prevalent.»
«If you do get the flu after going for the shot, it just means that you contracted a
different strain that wasn't included in the
vaccine,» says Dr. Phillips.
Like the flu there are thousands of
different strains of kennel cough, and while the
vaccine helps to prevent the most common
strains, it is not a guarantee that your dog will still not develop kennel cough, even if properly vaccinated.
There are many
different strains of the FIV virus and it is not entirely clear as of yet how well the available
vaccine protects against all these
different strains, but studies suggests that it is able to provide a valuable degree of protection for cats at risk of exposure.
This information provides only a small look at some of the advantages and results you'll see from a
vaccine that offers cross-protection against
different swine influenza
strains.
However, there are eight
different strains of the bacteria that affect dogs, and the
vaccine only protects against two of those
strains (icterohaemorrhagie and canicola).
What's
different about this variant is not that the
vaccine isn't effective against it, and not that adult dogs can get it, too (they can get older
strains of parvo, too, but incidence is much lower than in puppies because adult dogs are easier to vaccinate effectively), but that that virus has characteristics that make it harder to diagnose with the currently standard tests.
We utilize the most broad spectrum
vaccine available which protects against 4
different strains (Serovars) of the disease.
Every year, the
vaccine is
different because every year there is a new
strain of virus.
At this time, it is also unknown whether the current CIV
vaccine, developed to protect against a
different strain of the virus (Influenza A H3N8), will be effective in preventing Influenza A H3N2.
Some infectious agents exist in
different strains or evolve into new
strains that are not directly covered by the
vaccines given.
Based on that information and on the recommendations of the FDA's
Vaccines and Related Biological Products Advisory Committee, the FDA selects the different influenza strains each year that manufacturers should include in their vaccines for the U.S. population for the upcoming influenza
Vaccines and Related Biological Products Advisory Committee, the FDA selects the
different influenza
strains each year that manufacturers should include in their
vaccines for the U.S. population for the upcoming influenza
vaccines for the U.S. population for the upcoming influenza season.