Sentences with phrase «differentiated organ cells»

Stem cells could likewise be reprogrammed into differentiated organ cells.

Not exact matches

Remarkably, given the complexity of the kidney, the cells differentiated into exactly those required in the different compartments of the organ.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

One likely reason for this is that animals undergo cellular differentiation; human life begins as a single cell that differentiates into the various cell types needed for different organs, body parts, blood, the immune system, etc..

Since embryonic stem cells can differentiate into any type of tissue, they have the potential to treat an almost unending array of medical conditions — replacing damaged or lost body parts or tissues, slowing degenerative diseases, even growing new organs.

Recent experiments, for instance, suggest that when an organ lacks LGR -5-positive cells, differentiated cells may be able to «dedifferentiate» and repair tissues — a radical change from the one - way street toward specific identities that stem cells were thought to travel.

The EMT is a biological process wherein epithelial cells (cells that line the cavities and surfaces of blood vessels and organs) become mesenchymal (skeletal) stem cells that can move throughout the body and differentiate into a variety of cell types.

Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn - out or damaged organs and tissues.

During embryonic development, organ - specific cell types are formed from pluripotent stem cells, which can differentiate into all cell types of the human body.

But the numerous cells in the peanut - shaped fossil were not differentiated into organs; they all looked alike.

At that key point, Takebe added two more types of cell known to help to recreate organ - like function in animals: endothelial cells, which line blood vessels, taken from an umbilical cord; and mesenchymal cells, which can differentiate into bone, cartilage or fat, taken from bone marrow.

The phenotype of NP cells generated ex vivo (Figure S8) closely resembles that of central memory CD4 + T cells found in vivo, which persist for years in secondary lymphoid organs and can differentiate into effector memory CD4 + T cells [45].

During fibrosis these cells differentiate into myofibroblasts, causing scarring and organ failure.

The Salk researchers stopped the cells from differentiating further, but each germ layer was theoretically capable of giving rise to specific tissues and organs.

«The region selective - state of these stem cells is entirely novel for laboratory - cultured stem cells and offers important insight into how human stem cells might be differentiated into derivatives that give rise to a wide range of tissues and organs,» says Jun Wu, a postdoctoral researcher in Izpisua Belmonte's lab and first author of the new paper.

Successful cell replacement depends on the ability of donor cells to differentiate into all functional cell types lost in the target organ.

Organ renewal and cell divisions by differentiated cells in Drosophila.

A striking aspect of organ regeneration is how injury transforms differentiated, functional tissue into proliferative, regenerative cells that coordinate tissue replacement.

New planarian tissues and organs are created by neoblasts - adult stem cells that share certain characteristics with embryonic stem cells and can differentiate into essentially all the cells in adult animals.

In a developing embryo, stem cells can differentiate into all the specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.

Suzuki, possibly inspired by his new job as a research scientist at the Research Unit for Organ Regeneration in Kobe, Japan, explains it this way: «Just as humans can start over in life, differentiated cells can also take on other fates following the generation of undifferentiated stem cells.»

The leaf boundary regions separate differentiated organs from undifferentiated stem cells in plants.

Your immune system is a complex network of specialized cells and organs that work hard to differentiate between self and «non-self» — that is, between what's you and what's not.