Sentences with phrase «differentiation capacity»
"Differentiation capacity" refers to an organism's or cell's ability to transform into different specialized types of cells. It signifies their potential to change and develop into diverse cell types, allowing them to perform various functions in the body. Full definition
Converted NSCs exhibited multipotential differentiation capacity, generating both astrocytes and neurons, and transcriptional patterns and functionality indicative of an NSC identity.
stemcellsportal.com
Can we artificially speed up or slow down cells and what affect will this have on differentiation capacity?
An important goal is therefore to identify the mechanisms by which Notch signaling exerts specific and distinct outcomes at different activity levels, in order to develop means to enhance the renewal and differentiation capacities of β - cell progenitors in the pancreas.
Interestingly, the medium paced cells had the highest tri-potential differentiation capacity, suggesting that this method may be useful in assessing the utility of an MSC population for therapeutic use.
One of the lines derived had higher levels of ACAN at 2 weeks and during 3D culture formed high levels of extracellular matrix (Alcian blue van Gieson staining), high levels of collagen II deposition and increasing expression levels of ACAN, SOX9, and COL2A1 types A and B, overall suggesting a high cartilage differentiation capacity.