By varying the compositions of lipids, cues, and
diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform.
One experiment examined the effect of the protein insulin on ADDLs (amyloid - beta derived
diffusible ligands), toxic proteins that build up in the brains of Alzheimer's patients, causing cell death.
By tracking a limited ensemble
of diffusible molecules over time, the spatiotemporal dynamics of molecules and the connectivity within microcompartments can be obtained in addition to superresolved (tracking and localization microscopy, TALM).
However, it's also a highly
diffusible gas; hence, H2 production allows mycobacteria to produce energy by dissipating excess fuel as H2.
The β2 - adrenergic receptor (β2AR) is a well - studied prototype for heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors (GPCRs) that respond to
diffusible hormones and neurotransmitters.
Such communication through pheromones or
other diffusible substances points to a nonindividual autonomous mode of aging regulation.
Pseudomonas fluorescens UM270 is a rhizosphere - colonizing bacterium that produces
multiple diffusible and volatile compounds involved in plant growth - promoting activities.
Amyloid - β 42 (Aβ42) has a strong ability to oligomerize to
form diffusible oligomers as well as larger polymers called fibrils that form insoluble amyloid plaques, a major hallmark of AD.
Pre-Brainbow techniques, such as Golgi staining, injection of
diffusible labels, or electron microscopy of stained sections, were limited due to low resolution or were very time - intensive, necessitating the development of a new technique.
Once produced, NO is
freely diffusible and enters target cells and into the airway and can be detected in exhaled breath of all humans.
We are interested in how CAFs stimulate invasion of cancer cells: by
secreting diffusible pro-invasive molecules, preparing «the road», «carrying» cancer cells and / or by providing direction.
Lemon verbena is not only used medicinally; its strong lemony fragrance, manufactured by distilling oil from the plant's leaves, is a widely used ingredient in perfumes and aromatherapy products, including candles and
diffusible oils.
This metabolic mode depends on the production and recycling of molecular hydrogen, a high - energy fuel and
diffusible gas.
To see it, Nägerl and colleagues coupled
a diffusible, fluorescent dye with super-resolution microscopy, in this case stimulated emission depletion (STED) microscopy, to generate high - quality, 3D reconstructions of the tissue and spaces within brain slices kept alive outside the body.
The structure provides a high - resolution view of a human G protein — coupled receptor bound to
a diffusible ligand.
Then it took seven more years to produce the first crystal structure of a GPCR bound to
a diffusible ligand, the b2 - adrenergic receptor (a receptor for epinephrine), this one published by the Kobilka lab in 2007, during Granier's second and final postdoctoral year.
The Horch lab previously correlated upregulation of sema2a — the gene that codes for
a diffusible semaphorin protein in invertebrates — with this compensatory growth.
In most cases the goal for dog cancer treatment is the complete removal of cancerous cells remains unachievable due to quick, progressive and
diffusible (spreading deep into the tissue) nature of cancerous cells.