Large pale yellow spots are fat droplets, smaller ones waste -
digesting lysosomes.
Not exact matches
Finally, APs fuse with
lysosomes to form autolysosomes (ALs) that
digest and release the breakdown products for re-use, much like a recycling plant would repurpose incoming trash.
The virus, with its hitchhiking antibodies still bound to it, then attaches to a cell and enters the
lysosome — a membrane - bound structure within the cell that is filled with enzymes for
digesting foreign and cellular components.
So the idea would be to identify the enzymes these organisms use to
digest lysosomal wastes, modify them a bit to help them work in the slightly different environment of the human
lysosome, and then deliver them to where they need to go in our cells.
After fusion of autophagosomes with
lysosomes, the protein content is
digested by a variety of proteases, called cathepsins [130].
Lysosomes not only
digest human junk, they seek out bacteria and
digest them.
If one of those gene pairs is defective, the
lysosomes can not
digest the particular substance under that enzyme's control and that substance can build up within the cell — eventually killing it.