Sentences with phrase «direct cell differentiation»

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[Praveen R. Arany et al, Photoactivation of Endogenous Latent Transforming Growth Factor — β1 Directs Dental Stem Cell Differentiation for Regeneration] Could a light - based treatment for cavities and chipped teeth eventually be in the offing for people?

Directing stem cell differentiation is like following a complex recipe, involving a long list of ingredients and steps that make the process costly and inefficient.

But like the medieval alchemists, today's cloning and stem cell biologists are working largely with processes they don't fully understand: What actually happens inside the oocyte to reprogram the nucleus is still a mystery, and scientists have a lot to learn before they can direct a cell's differentiation as smoothly as nature's program of development does every time fertilized egg gives rise to the multiple cell types that make up a live baby.

The expression of specific genes in a particular root cell determine its fate — the zone in which it will function, Subramanian explained, so he is identifying which micro-RNAs direct gene expression to achieve this differentiation.

We report here the adoptive transfer, to patients with metastatic melanoma, of highly selected tumor - reactive T cells directed against overexpressed self - derived differentiation antigens after a nonmyeloablative conditioning regimen.

Special focus is placed on Rho - kinase inhibition, relating to its potential to promote and support extracellular matrix production in cultured chondrocytes and its role in fibroblast cells as a part of direct chemical cellular differentiation.

His findings could help researchers devise ways to repair or replace damaged tissues by directing cells into specific differentiation paths.

The exploration of the therapeutic potential of stem cells requires the characterization of their biological properties, the deciphering of the mechanisms that underlie their pluripotency and their capacity at differentiation, by the understanding of the signals that direct their fate towards discrete cell phenotypes... Their therapeutic use requests further, in particular in the case of substitutive therapies, the analysis of their capacities of integration in injured adult tissues and of their potential tumorigenicity, as well as the development of original ways of delivery.

Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.

«This new understanding of the role played by scrawny may make it easier to expand stem cell populations in culture, and to direct stem cell differentiation in desired directions,» says Spradling.

Differentiation of a cell into a more specialized cell type is directed by cellular circuits.

«We can no longer view differentiated cells as being a static endpoint of the differentiation process,» says Izpisúa Belmonte, who also directs the CMRB.

The product combines pancreatic progenitor cells called PEC - 01, produced by a directed differentiation process, encapsulated with a semi-permeable device called the Encaptra ® Drug Delivery System, both are proprietary technologies.

A future aspect of our mouse work is directed towards use of ES cell differentiation in culture as a model for epigenetic decisions and stem cell manipulations.

The portfolio includes U.S. and foreign patents and applications directed to culture, expansion and scale - up of pluripotent stem cells and cell types derived therefrom, various differentiation processes for production of mesendoderm, definitive endoderm, PEC - 01, and endocrine precursors, as well as claims directed to the Company's Encaptra ® macro-encapsulation device platform.

(c) The ratio of beating EBs in directed differentiation of iPS cells of line 11.1 into cardiomyocytes was shown.

In this study, we analyzed three different cultures of neural cells carrying trisomy of chromosome 21, which were generated by directed differentiation from induced pluripotent stem cells (iPS cells).

Therefore, our results suggest a direct suppressive effect of VPA on the differentiation and immune function of Th1 and Th17 cells.

VPA suppresses Th1 and Th17 cell differentiation and immune function in vitro and in vivo through direct inhibition of Akt.

During that time, she applied her knowledge of the processes governing normal heart development to direct the differentiation of embryonic stem cells into the cardiac lineage.

Testosterone may even have a direct effect on fat cells via «inhibited adipogenic differentiation «[1].