Sentences with phrase «direct gene activity»

For the first time, scientists have shown that a genetic element on one chromosome may direct gene activity on another chromosome.

Not exact matches

This bundling of DNA acts as a switchboard for controlling genes» activity and directs a cell's complex molecular machinery.

The idea is that small chemical tags, such as acetylation, on chromatin marking active or inactive genes would self - propagate independently of the underlying DNA sequence and direct the activity of the genome.

In light of the widespread role of oxidative stress in the pathology of diverse human diseases and the ability of the Nrf2 - dependent antioxidant response gene network to protect against oxidative stress, considerable effort has been directed towards discovering compounds that can increase the activity of Nrf2.

UT MD Anderson Scientists Discover Secret Life of Chromatin (08/30/2011) A team of researchers directed by Dr. Sharon Dent, director of the Department of Epigenetics and Molecular Carcinogenesis and Center for Cancer Epigenetics, investigate a signaling activity of chromatin that is independent of its central role in gene transcription.

Through this mechanism, it would be possible for a cell to couple extracellular cues to maintenance of pluripotency through direct regulation of transcription factor activity, and to fine - tune gene expression as the extracellular environment dictates.

This activity can be directed to any gene of interest that can be inserted into the Ig locus [11].