Sentences with phrase «directed by genes»

Not all traits which are directed by genes are desirable.

Eigenberg returned to the same genre amid a cast of unknowns with the 2007 film The Trouble with Romance, directed by Gene Rhee.

ON THE TOWN (1949) ** / **** Image C Sound B - starring Gene Kelly, Frank Sinatra, Betty Garrett, Ann Miller screenplay by Adolph Green and Betty Comden, based on the play directed by Gene Kelly and Stanley Donen TAKE ME OUT TO THE BALL GAME (1949) ** / **** Image B + Sound A - Extras C starring Frank Sinatra, Esther Williams, Gene Kelly, Betty Garrett screenplay by Harry Tugeno and George Wells directed by Busby Berkeley ANCHORS AWEIGH (1945) ** / **** Image C + Sound B - Extras D starring Frank Sinatra, Kathryn Grayson, Gene Kelly, Dean Stockwell screenplay by Isobel Lennart directed by George Sidney

Not exact matches

By transferring genes that direct the production of fluorescent PER proteins into living flies, Kay and his colleagues have shown that each tissue carries an independent, photoreceptive clock.

It seems that some output genes are turned on by a direct interaction with the CLOCK protein.

On the other hand, by deciding that an EST sequence does not provide an adequate written description of a claim directed to «a gene,» the PTO has preserved the possibility for a gene itself to be patented once its full - length sequence is determined.

Initial testing of mTOR inhibition was achieved by direct deletion of the mTOR gene in mice.

The direct methylation of the DNA changes the gene expression permanently if it takes place in the control regions of genes (so - called CpG islands), that have been made accessible by the modification of the histones.

They will then reproduce as directed by their own genes but using the resources of the host cell.

We now have the first direct evidence that switching off certain genes — something that can be caused by our lifestyle or environment — can trigger tumours, without mutating the DNA itself.

Taking a different approach, the researchers took a set of regulatory genes, called a GAL regulon, that normally processes galactose — a favorite on the yeast menu of nutrients — and replaced some of the genes with those that become activated by, and direct the breakdown of, xylose.

Subsequent procedures included mammalian somatic cell nuclear transfer, cell fusion, induction of pluripotency by ectopic gene expression, and direct reprogramming.

But a study that sheds light on the direct causal relationship between smoking and mortality by investigating genes has never been published before:

This is done either by direct injection with micro-pipettes or by infecting the plant with a bacterium such as Agrobacterium tumefaciens carrying the modified gene.

The technology allowed researchers to chart hierarchies, or cascades, of genes and to track the process by which one gene after another turns on, directing the embryo's development.

More than 20 years ago, in a study that triggered both scientific and cultural controversy, the molecular biologist offered the first direct evidence of a «gay gene,» by identifying a stretch on the X chromosome likely associated with homosexuality.

The case for direct interaction was bolstered by similarities between gene expression profiles of plants with various deficiencies in photoreceptors and COP1.

When the researchers looked at the role of genes that were methylated by genes with code differences related to ASD, including additional genes beyond those with direct code changes, they found that the majority were involved in biological pathways that were important in immune function.

One study, led by Gene Serabyn of JPL, the overall lead of the Keck vortex project, presents the first direct image of the brown dwarf called HIP 79124 B.

Unfortunately, direct comparisons of gene expression profiles obtained in independent, publicly available microarray experiments are typically compromised by substantial, experiment - specific biases.

However, the researchers took a set of regulatory genes, called a GAL regulon that normally processes galactose and replaced some of the genes with those that become activated by and direct the breakdown of xylose.

These plasmids use fluorescent proteins flanked by long regions of homology to the gene of interest to promote homology directed repair after a CRISPR / Cas9 induced break.

This study will combine direct tumor cell killing (TK) and immune - mediated stimulatory (Flt3L) gene transfer approaches delivered by first generation adenoviral vectors.

The first step in both direct and cell - based gene therapy is packaging a therapeutic transgene into a delivery vehicle (e.g., a viral vector), followed by expansion of its host cell lines to produce high - enough vector concentrations.

Introducing new DNA often is achieved by viral transduction of target cells with a therapeutic transgene, through either a direct or cell - based gene therapy modality.

In comparison with the direct transcriptional response of IRF - 1 to IFNα, the RIG - G mRNA induction was entirely blocked by cycloheximide (Fig. 1B), indicating that the RIG - G was not a primary responsive gene in IFNα - induced JAK - STAT pathway.

UT MD Anderson Scientists Discover Secret Life of Chromatin (08/30/2011) A team of researchers directed by Dr. Sharon Dent, director of the Department of Epigenetics and Molecular Carcinogenesis and Center for Cancer Epigenetics, investigate a signaling activity of chromatin that is independent of its central role in gene transcription.

The statistical analysis of gene - families, resistance genes and mobile elements was performed by ShotgunFunctionalizeR 1.03 using custom - made annotations and the Poisson model for direct comparisons [24].

In about a third of the children who had these de novo BCA mutations and a developmental disorder, the disorder showed a direct link to one of the genes that had been disrupted by the BCA.

Furthermore, chromatin contact maps that link enhancers to promoter regions in a direct way allow identification of genes that can be regulated by the disease variants.

Site - directed mutagenesis by gene targeting in mouse embryo - derived stem cells.

Although dCas9 can tether different effectors, several dCas9 fusions (e.g., dCas9 - VP64 activator and dCas9 - KRAB repressor) can not be co-introduced with sgRNAs to regulate two set of genes differently since both fusions will bind to both set of genes directed by both sets of sgRNAs (Fig 1).

The co ‐ expression of neighboring genes at the mRNA level is driven by chromatin fluctuations and direct regulatory interference.

By far, the vast majority of genes are the thousands that direct all our biochemical processes that render us susceptible to the many chronic diseases so many people are experiencing today.

Gene Autry and his sidekick, Smiley Burnette, are suspected of cattle rustling in this action - packed Republic Pictures Western directed by former actor Mack V. Wright.

Acting is all: Lemmon and Matthau are terrific in their first teaming in this highly amusing comedy, which is sharply written by Neil Simon but poorly directed by theater helmer Gene Saks.

*** / **** Image A Sound B Extras A + starring Gene Barry, Ann Robinson, Les Tremayne screenplay by Barré Lyndon, based on the novel by H.G. Wells directed by Byron Haskin

The original film was directed by the late, great Tony Scott and starred Will Smith during the period when he was fully emerging as the most famous movie star on the planet and Gene Hackman when he was still, you know, regularly acting and being one of the finest actors all time.

The Scoop: 2001 R, directed by Wes Anderson and starring Gene Hackman, Gwyneth Paltrow, Ben Stiller, and Owen Wilson

The outrage expressed by interviewees Carson, Mike Ditka, Daryl Johnston, Donnie Green and others — whether offering personal tales of woe or sticking up for others — is directed mostly at NFL Players Assn. head Gene Upshaw, who notoriously denied a connection between game - time concussions and increased instances of dementia among retirees.

Unforgiven Year: 1992 Directed by: Clint Eastwood Starring: Clint Eastwood, Gene Hackman, Morgan Freeman, Frances Fisher Why it's essential: It's weird to think about after Eastwood became such a reliable Oscar fave, but back in 1992, he was really just another actor who wanted to direct.

* 1/2 / **** Image A Sound A - Extras B starring Owen Wilson, Gene Hackman, Joaquim de Almeida, David Keith screenplay by David Veloz and Zak Penn directed by John Moore

**** / **** Image A Sound A - Extras B starring Gene Kelly, Donald O'Connor, Debbie Reynolds, Cyd Charisse screenplay by Betty Comden and Adolph Green directed by Stanley Donen

Cast: Christopher Reeve, Margot Kidder, Terence Stamp, Gene Hackman, Sarah Douglas, Jackie Cooper, Jack O'Halloran, Susannah York, Valerie Perrine, Ned Beatty Director: Richard Lester (some scenes directed by Richard Donner) Screenplay: Mario Puzo, David Newman, Leslie Newman Review published June 15, 2004

He produced The Grapes of Wrath (1940) starring Henry Fonda, directed by John Ford from the novel by John Steinbeck, The Song of Bernadette (1943) by Henry King with Jennifer Jones, that won Best Picture, Best Director and Best Actress at the first Golden Globes in 1944, Laura (1944) by Otto Preminger with Gene Tierny, A Tree Grows in Brooklyn (1945) and Gentleman's Agreement (1949) with Gregory Peck, both directed by Eliza Kazan, All About Eve (1950) with Bette Davis directed by Joseph Mankiewicz.

«Plunder Road» (1957), 4:45 p.m.: In this little - known noir directed by Hubert Cornfield, five men, led by Gene Raymond (in a rare villainous turn), try to pull off the perfect heist: stealing $ 10 million in gold from a train headed for a U.S. Mint branch in San Francisco.

*** 1/2 / **** Image A Sound A Extras A - starring Richard Widmark, Gene Tierney, Googie Withers, Hugh Marlowe screenplay by Jo Eisinger, based on the novel by Gerald Kersh directed by Jules Dassin

LAURA *** / **** Image B Sound B - Extras B starring Gene Tierney, Dana Andrews, Vincent Price, Judith Anderson screenplay by Jay Dratler and Samuel Hoffenstein and Betty Reinhardt, based on the novel by Vera Caspary directed by Otto Preminger PINKY * / **** Image C Sound B - Extras A + starring Jeanne Crain, Ethel Barrymore, Ethel Waters, William Lundigan screenplay by Philip Dunne and Dudley Nichols, from a novel by Cid Ricketts Sumner directed by Elia Kazan by Walter Chaw A camp classic of a very particular variety, Otto Preminger's stylish, pedigreed Laura might best be read as a satire of Hitchcock's Rebecca, reuniting that film's Judith Anderson with another late, lamented mistress and acres more scenery to chew.

Hosted by the Gene Siskel Film Center, the month - long Chicago European Union Film Festival (CEUFF) featured 15 films directed by women (15 out of 62 = ~ 25 % = a record high for this event).

The pilot was written by Suits creator and executive producer Aaron Korsh and executive producer Daniel Arkin, and was directed by Suits alum Anton Cropper The new series, which hails from Universal Cable Prods., is executive produced by Korsh, showrunner Arkin, Torres and Suits executive producers Doug Liman, David Bartis and Gene Klein of Hypnotic.