Not exact matches
In order to survive,
early single -
celled organisms could have used that signal to
direct repair, an evolutionary advance that he thinks survives today.
In
earlier studies involving animal models and human cancer
cell lines, researchers found that breast cancer spreads when three specific
cells are in
direct contact: an endothelial
cell (a type of
cell that lines the blood vessels), a perivascular macrophage (a type of immune
cell found near blood vessels), and a tumor
cell that produces high levels of Mena, a protein that enhances a cancer
cell's ability to spread.
Cells in the
early embryo are thus
directed to make a decision to either form bone or cartilage, depending on where they are.
The US Department of Energy's National Renewable Energy Laboratory (NREL) is collaborating with Oorja Protonics, a developer and manufacturer of
direct methanol fuel
cell technology (
earlier post) on a two - year project to deploy and demonstrate methanol fuel
cells for power pallet jacks in four commercial wholesale distribution centers.
«These are interesting results proving it is theoretically possible to «regress»
cells back to an
earlier stage in development when they are self - perpetuating and still have the potential to be
directed to become a whole range of different
cell types, whether nerve
cells, heart muscle or bone.
They included cloning (somatic
cell nuclear transfer, accomplished in many placental mammals), stem
cell gametogenesis (has been done in mice),
direct engineering of
early stage embryos (has been done in several mammals), embryonic stem
cell editing, and primordial germ
cell (PGC) editing.
That we observe
cell sorting in EB culture also provides
direct evidence, albeit in vitro, for the differential adhesion model proposed for the resolution of
early PrEn and PrEc in the mammalian blastocyst in this same paper [56].
For example, the same cellular signals that guide
early heart development can be used to
direct stem
cells to become the different heart
cell types needed for modeling disease in a dish.
We believe that a similar
early precursor may exist to the PrEc lineage (Figure 9), and while we have no
direct evidence for this, we did observe Oct4 positive
cells that neither expressed Nanog nor the Venus transgene and there also appears a slight enrichment of
early neural markers in the V − S + population (Figure 4).
The good news is that if markers for these tubal
cells can be found, then blood tests, advanced Pap smears, or
direct tests on tubal tissue might spot ovarian cancer
earlier, the study authors said.