The disabled gene codes for the protein PD - 1, which normally puts the brakes on a cell's immune response: cancers take advantage of that function to proliferate.
Not exact matches
The experiment's final product is equivalent to the naturally occurring genetic
code of M. genitalium, with two minor exceptions: The scientists
disabled the
gene that gave the bug power to infect human cells, and they added a few «watermarks,» short strips of signature genetic
code that identify the product as man - made.
Soon after researchers began to sequence individual genomes 5 years ago, they realized that everyone's DNA seems to have major mutations that
disable the protein for which the
gene codes.
Human Argonaute - 2 (hAgo2) is known as «slicer» for its unique ability among the 4 human Argonaute proteins to directly cut messenger RNA — which carries the information
coded in genomic DNA to make a protein — and thus
disable «messages» generated from
genes.
Then, scientists can either
disable the
gene in question or provide substitute DNA to repair the broken section — rewriting the genetic
code at that location.