Scientists at UMass Medical School have performed the first CRISPR / Cas9 screen to
discover human proteins that Zika virus needs for replication.
Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR / Cas9 screen to
discover human proteins that Zika virus needs for replication.
Not exact matches
Some of the marketing material highlighted in Lion's cross claim includes: «A2 will improve
human health through the consumption of a2 dairy milk products», «studies suggest that milk containing only the A2 type of
protein may benefit you and your family if you're concerned with certain allergies, immune function or digestive wellbeing» and «there is significant evidence to suggest that beta casein A1 may be a primary risk factor for heart disease in adult men and also be involved in the progression of insulin dependent diabetes in children... Beta casein A1... is the most powerful risk factor ever
discovered.»
This is what Janow
discovered at the suggestion of the aforementioned big customers Old Mother Hubbard and Nestle Purina: brown rice
protein is healthier and safer for living creatures, including
humans.
To that end, Oxford grad student Samantha Brown reported in a poster that she
discovered a
human bone fragment by using a new technique, called ZooMS, to scan 2315 bones from the cave for uniquely
human proteins.
Given that the newly
discovered protein FGB1 has such a high affinity and specificity to beta -1,6-glucans from fungi cell walls, it is possibly suitable for the diagnosis of
human infections.
The new drug - like compounds
discovered by Vogel and her co-authors offer hope that using a computer - generated P - gp model, explained here http://bit.ly/1LVmR7a, developed to accurately mimic the physical, chemical and biological functions of the
protein in the
human body, will speed up the drug discovery process and work in real life as well.
The paper focuses on two key molecular players in the story of influenza infection: a
human protein called TRIM25, which was recently
discovered to play an important role in the
human immune response to flu infection; and a
protein called NS1 present in all strains of the influenza A virus and shown to bind TRIM25 to keep it from doing its job.
Two teams have independently
discovered that a single regulatory
protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long - standing mystery in parasite biology with important implications for
human health.
Stivers knew that depleting nucleotides by breaking them down into pieces that quickly leave the cell is precisely the job of SAMHD1, a
protein recently
discovered in
humans but thought to have first evolved in bacteria as a defense against viruses.
Researchers have
discovered that a
protein which controls anxiety in
humans has the same molecular ancestor as one which causes insects to moult when they outgrow their skins.
The Ras gene, which codes for the Ras
proteins, was
discovered in the 1960s, and represents the first gene identified with the potential to cause cancer in
humans.
The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many
proteins important in the cell cycle and signaling networks found in
human biology having first been
discovered in yeast.
Researchers have
discovered that the toxic
protein responsible for progeria is actually produced at low levels in all
humans, possibly accumulating as we age.
In research published in Molecular Cell, Rutgers scientists
discovered that a
protein (p62), which is supposed to act as an antioxidant to prevent cell damage, was not working efficiently in laboratory mice with liver and heart disease that mimicked these conditions in
humans.
A team led by Jos Jonkers at the Netherlands Cancer Institute
discovered that a mouse harboring an analog of the cancer - associated
human BRCA1 mutation, BRCA1184delAG, expresses a BRCA1
protein that is missing a structural component called a RING domain.
Juan Bonifacino's lab at the National Institute of Child Health and
Human Development, for one, had
discovered the role a certain
protein plays as asymptomatic infection progresses to AIDS but testing of a new class of potential HIV medications had to be stopped due to the shutdown.
In a study, published in mBio February 26, 2013, the University of Southampton team
discovered that a MenB
protein called the Adhesin Complex Protein (ACP) is a new molecule that the MenB bacterium uses to stick to human
protein called the Adhesin Complex
Protein (ACP) is a new molecule that the MenB bacterium uses to stick to human
Protein (ACP) is a new molecule that the MenB bacterium uses to stick to
human cells.
Researchers studying a
protein that causes a hereditary degenerative brain disease in
humans have
discovered that the
human, mouse and hamster forms of the
protein, which have nearly identical amino acid sequences, exhibit distinct three - dimensional structures at the atomic level.
However, Dr. Kissler's group
discovered that reducing levels of the RGS1
protein did not slow the progression of the disease in mouse models, suggesting that it may not offer much potential for
human treatment.
But researchers in OSU's College of Science have
discovered a key new
protein in a snail, Biomphalaria glabrata, that hosts and releases Schistosoma mansoni parasites that infect
humans.
Joshua - Tor also collaborates with Bruce Stillman to solve mysteries about the
human Origin Replication Complex (ORC), the «initiation
protein» for DNA replication, which Stillman's team
discovered, in yeast, in 1992.
Some additional experiments in cells confirmed their hunch about the physical interaction between the TDP - 43 and SCA2
proteins, but the scientists wondered whether their discovery is applicable to
humans, considering they
discovered it in yeast cells.
Prusiner won the Nobel Prize in Physiology or Medicine in 1997 for
discovering that the neurodegenerative diseases known as spongiform encephalopathies, which include «mad cow disease,» are caused by an infectious form of a
protein that exists in all mammals and birds examined, including
humans.
Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have
discovered that a
protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing
human brain and retina.
But with millions of cells — all carrying the
human disease — to work with, Zhang's research group
discovered the source of the tangles in the
protein subunits that compose the neurofilaments.
We believe that leveraging
human intuition through creation of a scientific game for drug discovery can not only provide a new avenue to
discover therapeutic drugs for
protein targets, but can also contribute to the development of new sophisticated algorithms to use in computer aided drug design.
July 3, 2013 New mechanism for
human gene expression
discovered In a study that could change the way scientists view the process of
protein production in
humans, University of Chicago researchers have found a single gene that encodes two separate
proteins from the same sequence of messenger RNA.
Biologists recently
discovered skin
proteins shared by
humans and turtles which developed in a common ancestor roughly 310 million years ago.
Two
proteins she
discovered help ensure proper partitioning of chromosomes during meiosis (improper partitioning is a major cause of
human birth defects).
How Things Grow, Including Cancer A
protein discovered in fruit fly eyes has brought a Johns Hopkins team closer to understanding how the
human heart and other organs automatically determine when they are the correct size, a piece of information that may hold clues to controlling cancer.
Discovered two
proteins crucial for proper partitioning of chromosomes during meiosis (improper partitioning is a major cause of
human birth defects)
Chinese scientists
discovered tiny,
protein - based biological compasses in fruit flies that also appear in pigeon, rat, whale, butterfly and
human cells.
A Japanese scientist has reportedly
discovered a way to create edible steaks based on
proteins from
human excrement.