Sentences with phrase «discovered growth factors»

Not exact matches

It was also a step in the direction of discovering their true relationship.2 One principal factor in the discovery of the relationship between church and mission was the growth of the younger churches.

In earlier work, Paller's lab had discovered that depleting an enzyme called GM3 synthase made cells particularly sensitive to growth factors and led to normal wound healing despite diabetic conditions.

What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give cancer cells properties of immune cells by supplying the surface of the cancer cell with a receptor that normally only exists on the white blood cells that travel through the lymphatic system.

Patterson, one of the few scientists who began studying the role of immune molecules in neurons before Shatz, has long focused on cytokines, messenger molecules that regulate inflammation in the body and (as Patterson eventually discovered) act as growth factors in the developing brain.

In 1991, Japanese researchers discovered that Lion's Mane contains two novel classes of nerve growth factor — molecules called hericenones and erinacines — that stimulate the differentiation and re-myelination of neurons.

Now, researchers have discovered that non-beta cells in the pancreas can be transformed into insulin - producing cells, merely by exposing them to a growth factor called BMP - 7.

However, 2 years ago, Terry Smith of the Harbor - University of California, Los Angeles, Medical Center in Torrance and colleagues discovered that in patients with Graves disease — an autoimmune disorder that attacks the thyroid gland and eyes — fibroblasts make chemokines when so - called immunoglobulin G antibodies in the blood activate a protein called the insulin - like growth factor 1 (IGF - 1) receptor.

Nerve growth factor was discovered in the 1950s by Dr. Rita Levi - Montalcini, who shared a Nobel Prize with Stanley Cohen in Physiology and Medicine in 1986.

Duke Regeneration Next researchers discovered that a protein in the glia called connective tissue growth factor, or CTGF, is crucial for this process.

In 1956 Daughaday discovered the hormone now called insulin - like growth factor 1, or IGF - 1.

A new study just published in the journal Glia and available online on July 11th, details the newly discovered mechanism by which astrocytes are involved in inhibitory synapse formation and presents strong evidence that Transforming Growth Factor Beta 1 (TGF β1), a protein produced by many cell types (including astrocytes) is a key player in this process.

«Discovering the factors involved in granuloma control vs those not able to control bacterial growth is a critical step in potentially developing treatments that could «freeze» granulomas into a protective state in the two billion latent carriers,» explains Grace Peng, Ph.D., Director of the NIBIB program for Mathematical Modeling, Simulation and Analysis.

Josef Singer and Judith Fazekas, both lead authors of the study, discovered that a receptor frequently found on human tumor cells (epidermal growth factor receptor or EGFR) is nearly 100 percent identical with the EGF receptor in dogs.

The team also performed a biochemical screen to identify molecules expressed in scar tissue and discovered relatively high levels of factors that support axon growth.

Alice Shaw recalls a signal moment in 2004 — just as she was finishing her oncology fellowship at MIT — when scientists discovered that mutations in a gene for epidermal growth factor receptor (EGFR) were the culprits in about 10 to 15 percent of lung cancer patients.

By studying the brains of adult birds, scientists may discover the cells that give birth to different kinds of neurons and the growth factors that nurture them.

Bernard and her co-author Debrup Chakraborty, a postdoctoral student in her lab, studied mice that were fed a high - fat diet and discovered that this higher - risk layer of fat produced larger amounts of the fibroblast growth factor - 2, or FGF2, protein when compared to the subcutaneous fat.

At the time, Martin Cohn, an evolutionary developmental biologist at the University of Florida in Gainesville, discovered snake embryos had a different pattern of activity of certain genes than other reptiles and that applying a growth factor could make those embryos start to grow limbs.

A team of scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) discovered a new bone - forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has implications for regenerative medicine.

«We discovered it helps to put the stem cells in with some buddies that give off growth factors.»

His research has also discovered a novel mechanism to regulate neurotrophic growth factor - associated signaling pathways by miRNAs in context of PD and Alzheimer's disease (AD), and a role of dysfunctional bioenergetics in the pathogenesis of late - onset AD.

During his doctoral and post-doctoral work under the mentorship of Jeffrey Goldberg, MD, PhD, and Larry Benowitz, PhD, Dr. Trakhtenberg discovered (1) how Set - β and PP2A proteins regulate axon growth; (2) the role of serotonin receptor 2C in neurite growth and processing of visual information; and (3) that inhibiting the transcription factor Klf9 acts synergistically with zinc chelation in stimulating axon regeneration.

«We discovered that this incredible region is a patchwork mosaic of trees with chemical signatures organized into communities to maximize their growth potential given their local soils and elevation — two geological factors they must negotiate as living organisms.

About Scholar Rock Scholar Rock is discovering and developing a pipeline of innovative new medicines to treat a range of serious diseases in which growth factors play a fundamental role, including neuromuscular diseases, cancer and fibrosis.

Knudson's revolutionary two - hit theory of cancer formation enabled me to discover the first imprinted tumor suppressor gene, the Insulin like Growth Factor 2 Receptor (IGF2R), propelling me into the field of epigenetics.