Sentences with phrase «discovered sequence of genes»

Not exact matches

An international team of scientists has sequenced the genome of an octopus, bringing researchers closer to discovering the genes involved in the creature's unusual biology, including its ability to change skin color and texture and a distributed brain that allows its eight arms to move independently.

By characterising the DNA sequence of these individuals, the project gained insight into the contribution of rare variants to a broad range of disease scenarios, and discovered new genetic variants and genes underpinning disease risk.

Publishing their findings in the open - access journal Nature Communications, the researchers discovered DNA sequences for «control dials» that consistently produce very high levels of gene activity.

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

Using a battery of comparative tests to study the genome sequences of the giraffe and the okapi, the scientists discovered 70 genes that showed multiple signs of adaptations.

Significant differences were also discovered between the centenarians and the two control groups when their genotype frequencies were compared, in other words, the proportion of individuals with a specific gene sequence.

He told the ESHG meeting that of the 572 people he has sequenced so far, genes with strong links to cancer were discovered in 10 of them.

By performing DNA sequencing of more than 4,000 families affected by neurological problems, the two research teams independently discovered that a disease marked by reduced brain size and sensory and motor defects is caused by a mutation in a gene called CLP1, which is known to regulate tRNA metabolism in cells.

The evidence that the SWEET4c gene was selected during domestication was discovered by the team of Jeff Ross - Ibarra at UC Davis, while comparing SWEET4 sequences from modern maize against its wild ancestor Teosinte.

One - hundred - ten of the genes had clear similarities in sequence to known antibiotic - resistance genes, the team discovered, and 18 of those were 100 % identical to genes found in human pathogens.

A new sequencing technology based on longer sequence reads allows missing genes and missing forms of genetic variation to be discovered for the first time.

«We discovered the existence of a short DNA sequence capable of activating a specific Hox gene, and which is present only in placental mammals and marsupials», explains Ruben Schep, the first author of the article.

Other medical sequencing projects will use DNA sequencing to: discover new genes that are involved in common diseases; identify the genes responsible for dozens of relatively rare, single - gene (autosomal Mendelian) diseases; sequence all of the genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in genes known to contribute to certain common diseases.

«This work compares the complete genome sequences of all known species of Leptospira to discover which genes make this bacterium a pathogen.

Reykjavik, ICELAND, 12 October 2011 — deCODE genetics today announced that it has entered into a research collaboration with Pfizer Inc., the objective of which is to discover sequence variants associated with specific clinical phenotypes related to Systemic Lupus Erythematosis by utilizing deCODE's expertise in gene discovery.

After looking at 9 million genetic variants in those who were asparagus anosmic, they linked this deficiency to 871 individual sequence variations they discovered in chromosome 1, on genes associated with our sense of smell.

The SIGMA project aims to develop novel biomedical approaches to treat this devastating disease by applying powerful sequencing technologies to discover the genes and key pathways underlying common varieties of cancer.

Piroska Szabó of the Van Andel Research Institute in Grand Rapids, Michigan, was once excited to think she'd discovered a new gene that expressed only the maternal allele — until she realized that the RNA sequences she was looking at were from a gene that had been misannotated as a nuclear gene, explaining the maternal - only inheritance.

July 3, 2013 New mechanism for human gene expression discovered In a study that could change the way scientists view the process of protein production in humans, University of Chicago researchers have found a single gene that encodes two separate proteins from the same sequence of messenger RNA.

Although these regions have been heavily studied, their sequences have led to unexpected observations; in the Bithorax complex for example, a glucose transporter gene was discovered in the midst of the complex of homeotic genes.

His laboratory has also discovered and characterized a significant number of novel genes contributing to autism and human neurodevelopmental disorders, and has recently applied whole - genome sequencing technologies and large - scale genomics datasets to prenatal detection and interpretation of structural variation in the genome.

The researchers then analyzed another 147 colorectal cancer cell lines in the same way for kinase - domain mutations in these genes, and then sequenced the entire coding region of all kinases that were mutated, in all discovering 46 new mutations.

By sequencing the DNA of different croc populations, the researchers discovered that the Abanda cave crocs were inheriting their own unique haplotypes, the term for a group of genes that one parent passes to its offspring, according to National Geographic.

With the completion and publication of multiple fully sequenced Woolly Mammoth genomes, the Church lab is discovering potential cold climate adaptations in different genes.

Genome Alberta announced C$ 25.2 million (US$ 22.2 million) in public / private funding over four years for two new genomic research projects, one targeted at enhanced recovery of fossil hydrocarbon resources from oil sands and coal beds through biological processes, the other focused on discovering plant genes that can be sequenced and used... Read more →

By zooming out of the specific suspected regions, we discovered differentially - methylated and acetylated regions that span large domains of sequence in the vicinity of the NR3C1 gene (Fig. 4a).