The project's launch featured a prominent ALS patient and research advocate: Pat Quinn, co-founder of the ALS Ice Bucket Challenge, an initially - derided social media stunt that went on to raise hundreds of millions of dollars for ALS research and may have spurred important new
discoveries about the disease's genetic roots.
«Everyone is eager to see the incredible deluge of molecular
discoveries about disease translated into prevention, diagnostics, and therapeutics for patients,» said Kathy Hudson, Ph.D., NIH deputy director for science, outreach and policy.
This program has been built upon the notion that progress can be expected only if new
discoveries about disease mechanisms are made, which pave the way to the development of better pharmacothearpies and / or prevention strategies.
Although no funds were allocated this year, the bill sets the stage for Minnesota to join several other states, including Wisconsin, that are racing for a claim on research that is expected to propel medicine toward major new treatments and
discoveries about disease pathways.
Not exact matches
Some crop — and even human —
diseases might be stopped dead in their tracks if researchers can harness a new
discovery about how pathogens first infect their hosts
With this
discovery, public officials also worked to improve water and sanitation efforts, create drainage systems in densely populated areas, and educate the general public
about how the
disease is transmitted.
Yet
discoveries about bird hearing could hold clues to treating deafness and neurodegenerative
diseases.
The journal provides cutting - edge research including results from animal models that are likely to apply to patients, studies in human tissue that provide new information
about therapies or
disease, and innovative reports of drug
discovery and development.
Sukel, however, is quick to caution that although today's studies on the subject of love may indeed explain a thing or two
about one's patterns in relationships, they can not serve as an instruction manual any more than DNA
discoveries can predict the
diseases you will contract.
But recent technological advances and a series of remarkable
discoveries in the past two years have provided key clues
about how Alzheimer's
disease ravages the brain.
A new
discovery about the immune system may allow doctors to treat harmful inflammation that damages the brain in neurodegenerative
diseases such as Alzheimer's.
These
discoveries build upon previous findings
about genes linked to Alzheimer's, such as the APOE - 4 gene, which is a powerful marker for late - onset Alzheimer's
disease;
about 40 percent of those diagnosed have this DNA variant.
Lyme
disease is a stealthy, often misdiagnosed
disease that was only recognized
about 40 years ago, but new
discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years — long before any humans walked on Earth.
Companies in the partnership supply compound libraries and drug
discovery expertise to the effort, while academic partners contribute knowledge
about the
disease and facilities for screens and assays.
While the new
discovery confirms scientists» ideas
about the evolution of
disease, the worrying implication is that the same process could cause other virulent strains of cholera to emerge at any time.
What started as the
discovery of an unknown
disease in Guam has spread to a line of ominous findings
about some of our most debilitating conditions and potential toxins lurking in bodies of water around the world.
Australian researchers have made a critical
discovery about a gene involved in muscular dystrophy that could lead to future therapies for the currently untreatable
disease.
Australian researchers have made a critical
discovery about a gene involved in muscular dystrophy that could lead to future therapies for the untreatable
disease.
Researchers and doctors are excited
about the
discovery, as there are no oral therapies approved in Canada for use at this very early stage of the
disease.
Although these mutations are relatively rare, their
discovery, reported in the January issue of Nature Genetics, could help point the way to other genes behind inherited epilepsies, which are thought to account for
about 40 % of all forms of the
disease.
Recent years have brought
about the
discovery of the fundamental contribution of epigenetics to the development of
disease.
While microbial forensics holds promise for unraveling
disease outbreaks, the FBI's
discovery also has political implications: The attacks originated in a U.S. Army lab, a fact that raises questions
about security in light of the massive biodefense expansion under the Bush administration.
Researchers led by Baylor College of Medicine have developed a new computational method to study the function of
disease - causing genes, starting with an important new
discovery about a gene associated with malaria — one of the biggest global health burdens.
«We didn't realize that was possible, and we think this
discovery could change our thinking
about not just IBD but other autoimmune disorders and infectious
diseases.»
A surprise
discovery that overturns decades of thinking
about how the body fixes proteins that come unraveled greatly expands opportunities for therapies to prevent
diseases such as Alzheimer's and Parkinson's, which have been linked to the accumulation of improperly folded proteins in the brain.
The
discovery of penicillin
about 90 years ago and the widespread introduction of antibiotics to combat infectious
diseases have revolutionized human medicine.
Scientists at the Montreal Neurological Institute and Hospital - The Neuro, McGill University, have made important
discoveries about a cellular process that occurs during normal brain development and may play an important role in neurodegenerative
diseases.
Lee: The most exciting aspect of genetics will always be the
discovery of how natural mutation causes
disease and in so doing, informing
about a basic rule of biology.
Investigating mouse models for biological for research The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug
discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare
diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects
about «Animal models for human
diseases» and recent developments in mouse models phenotyping imaging.
About deCODE deCODE is a biopharmaceutical company applying its
discoveries in human genetics to the development of diagnostics and drugs for common
diseases.
Mammoth hemoglobin, for example, may reveal information
about mammalian blood useful to treating human
diseases, and potentially the future of human space exploration (such as surviving cold environments); but the mutations that create mammoth hemoglobin need to be brought back to life for such
discoveries to happen.
«We are entering an exciting period of
discoveries in genetics that may provide new insights
about novel
disease pathways that can be explored for development of therapies.»
RA is a very unpleasant
disease to live with so any
discoveries we can make
about it are very valuable and could help future researchers develop new, more effective drug therapies.»
PD01A: Promising Animal Efficacy; Initial Human Safety and Hints of
Disease Modification At the time of our last post on α - synuclein vaccines, AFFiRiS had published several papers
about the AFFITOME immnotherapy
discovery platform [8 - 11] and had even begun their first Phase I trial of PD01A, but had kept nearly silent on many of the most elementary aspects of the vaccine.
On the opening day of the biggest ever Huntington's
disease therapeutics conference, we heard a lot
about studying the complexities of the brain, and the role of the huntingtin protein, still mysterious twenty years after its
discovery - but not very much
about drugs.
The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug
discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare
diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects
about «Animal models for human
diseases» and recent developments in mouse models phenotyping imaging.
At the two - day event, neuroscientists from across the nation gathered at Gladstone to present their
discoveries about neurological conditions, such as Alzheimer's
disease, Parkinson's
disease, and autism.
About deCODE genetics deCODE is a biopharmaceutical company applying its
discoveries in human genetics to the development of drugs for common
diseases.
This
discovery could affect how we think
about drug therapies for Huntington's
Disease.
Eric Verdin, MD, made a new
discovery about an ancient drug that could lead to alternative treatments for cancer and inflammatory
diseases.
In fact, the retired South African scientist who made the
discovery, Arnold Christianson, will be one of more than a dozen scientific speakers during the the first - ever, international scientific conference
about the
disease.
Different strains attack the body in different ways, meaning that
discoveries about the parasite often end up being strain - specific, rather than to the
disease in general.
Awareness
about 2 important publications from IMPC consortium 1 - The analysis of IMPC database that uncovers 360 new human
disease models has just been published: Meehan et al., (2017) Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Cons
disease models has just been published: Meehan et al., (2017)
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Cons
Disease model
discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
About deCODE deCODE is a biopharmaceutical company applying its
discoveries in human genetics to the development of drugs and diagnostics for common
diseases.
By studying the regenerative capabilities of diverse animals, we are making important
discoveries about age - related
diseases, including heart
disease, Alzheimer's and Parkinson's — even the process of aging itself.
Researchers at the University of Wisconsin — Madison have made a surprising and potentially crucial
discovery about Alexander
disease, a rare and fatal neurological disorder with no known cure.
Their
discoveries have provided new ways of thinking
about more common neurological disorders, including autism, intellectual disability, and Parkinson's
disease, and could lead to better treatments.
«I think uncovering this mechanism is an important basic
discovery that could lead to tangible ways of thinking
about design of therapeutic approaches for neurodegenerative
diseases in the near future,» said Haghighi.
The major significance of the paper is that it resolves the long - standing controversy
about the role of α - Syn Lewy bodies in the degeneration of substantia nigra dopamine neurons, thereby sharpening the focus on Lewy bodies as targets for
discovery of
disease modifying therapy for Parkinson patients.
What
about all the new
discoveries about the gluten / autoimmune
disease connection as promoted by Dr. Tom O'Bryan and discussed at length by scientists around the world at the Gluten Summit?