Not exact matches
The Company focuses on
discovering and developing
small molecule drugs directed against tumor and immune cell targets that control key metabolic pathways in the tumor microenvironment.
Shukla and colleagues
discovered that a
small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.
The new method gives scientists more power not only to find new antibody - based therapies, but also to
discover the biological pathways through which they work — pathways that may turn out to be more easily and cheaply targeted by
small -
molecule drugs.
In 1994, Schreiber and co-workers
discovered that the proteins FKBP12 and mTOR are the simultaneous targets of the
small molecule rapamycin, now approved for use as an immunosuppressant
drug given to patients after organ transplantations to help prevent rejection.
Memory improved in mice injected with a
small,
drug - like
molecule discovered by UC San Francisco researchers studying how cells respond to biological stress.
Discovering novel
small molecule drug leads depends on the ability to efficiently search chemical diversity.
It
discovers and develops novel,
small -
molecule drugs for the treatment of inflammatory and autoimmune diseases, as well as muscle disorders.
Rigel Pharmaceuticals, Inc is a clinical - stage
drug development company that
discovers and develops novel,
small -
molecule drugs for the treatment of inflammatory / autoimmune diseases, as well as for certain cancers and metabolic diseases.
Vertex Pharmaceuticals is engaged in the business of
discovering, developing and commercializing
small molecule drugs for the treatment of serious diseases.