Sentences with phrase «discovery of embryonic stem cells»

The major discovery of embryonic stem cells by Martin Evans in 1981 has indeed been recognized by a Lasker and other awards.

«People are jumping in very rapidly, much more rapidly than they did 10 years ago» after the initial discovery of embryonic stem cells, Thomson said.

The final group of stories is related to pluripotent stem cells: the discovery of embryonic stem cells (ESCs) in mice in 1981 by Martin Evans (it was a treat to see Evans, who won the Nobel Prize in 2007 for the research he discusses in the film!)

Not exact matches

Not that a principled moral objection shouldn't be enough, but, for those sitting on the fence, the additional discoveries of alternative sources of embryonic - type stem cells should be decisive.

But he notes that long - standing uncertainties surrounding European patents of techniques based on embryonic stem cells have meant that scientists and their attorneys are used to coming up with workarounds to protect discoveries.

But the factor that may make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing embryonic stem cell use, which are derived from human fetuses.

That breakthrough was one of a six - year chain of discoveries that included his 2007 work demonstrating the nuclear transfer method to create embryonic stem cells from a nonhuman primate.

This discovery by the scientists at the CRG provides an insight into stem cell - forming molecular mechanisms, and is therefore of great interest for studies on the early stages of life, during embryonic development.

Thirteen European stem cell scientists have issued a public appeal to the European Court of Justice (ECJ) not to prohibit patents on discoveries made with human embryonic stem (hES) cells.

The Nobel Assembly announced Professor Sir Martin as one of three winners for «a series of ground - breaking discoveries concerning embryonic stem cells and DNA recombination in mammals.»

My post-doctoral work on the identification of genes required for normal germ line development and fertility led to the discovery that the germ line is exquisitely sensitive to mutations in components of the mitotic spindle that have the potential to lead to aneuploidy — this sensitivity may also extend to embryonic and adult stem cells.

Smithies was awarded the Nobel Prize in 2007 alongside Mario Cappecchi and Martin Evans «for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells».

More Efficient, Effective Approach to Stem Cell Creation Dr. Ding's approach is one of a kind, but his work builds on a revolutionary discovery by another Gladstone scientist — Nobel Laureate Shinya Yamanaka, MD, PhD, who in 2007 revealed a process for transforming adult skin cells into cells that look and act like embryonic stem ceStem Cell Creation Dr. Ding's approach is one of a kind, but his work builds on a revolutionary discovery by another Gladstone scientist — Nobel Laureate Shinya Yamanaka, MD, PhD, who in 2007 revealed a process for transforming adult skin cells into cells that look and act like embryonic stem cestem cells.

This is hardly surprising, as the discovery, by Shinya Yamanaka, of the process to produce embryonic - like, fully pluripotent stem cells from ordinary somatic (body) cells has -LSB-...]

Dr. Yamanaka's Nobel prize - winning discovery of a way to turn adult skin cells into so - called induced pluripotent stem cells (iPS cells) that act like embryonic stem cells has radically advanced the fields of cell biology and stem - cell research.

San Diego, CA (June 3, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent No. 7,541,185 with method claims covering the use of endoderm cells derived from human embryonic stem cells (hESCs) for drug discovery.

This award, named after the Chapter's co-founder Richard Essey and his wife Sheila, this year recognizes the far - reaching, human - health impact of Dr. Yamanaka's Nobel Prize winning discovery of a way to transform adult skin cells into cells that act like embryonic stem cells.

As one example, using insights from embryonic development, Jessell has been able to convert embryonic stem cells into functioning motor neurons, facilitating the discovery of medicines to treat such diseases.

«This discovery will advance our understanding of stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark properties of ES cells, and help researchers with the rich source of information to better understand some of the unique features — such as self - renewal and pluripotency — of human embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.

The discovery, by scientists at Kyoto University and the University of Wisconsin - Madison, seemed to promise a way out of the bitter debates over embryonic - stem - cell research: rather than using human embryos as a source of stem cells, produce them from adult cells.

Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue - specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem - cell - based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource - based innovations.

Shinya Yamanaka MD, PhD, a senior investigator at the Gladstone Institutes has won the 2012 Nobel Prize in Physiology or Medicine for his discovery of how to transform ordinary adult skin cells into cells that, like embryonic stem cells, are capable of developing into any cell in the human body.

When scientists first isolated and cultured embryonic stem cells in 1998, they opened discovery into the pathways by which a few microscopic cells grow into the complex human body with all of its highly specialized parts.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Dr. Yamanaka's 2006 discovery of a way to turn adult skin cells into cells that act like embryonic stem cells has radically advanced the fields of cell biology and stem - cell research.

«President Obama's executive order today lifting federal restrictions on embryonic stem cell research is years overdue and will now allow the full potential of scientific research and discovery to be realized.