Sentences with phrase «discovery of gene variants»

Initiated in February 1998, and covering up to 12 common diseases, the five - year collaboration is focusing on the discovery of gene variants that predispose and / or contribute to the development of these diseases, with a major emphasis on six of them.

This is the prospect raised by the discovery of gene variants that seem to predict whether an individual will produce enough antibodies in response to a vaccine to protect them against disease.

November 10, 2005 Major discovery with rapid applicability to the development of new medicine Reykjavik, ICELAND, November 10, 2005 — A paper by a deCODE - led team of scientists published today presents the discovery of a gene variant conferring increased risk of...

Not exact matches

These discoveries build upon previous findings about genes linked to Alzheimer's, such as the APOE - 4 gene, which is a powerful marker for late - onset Alzheimer's disease; about 40 percent of those diagnosed have this DNA variant.

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

«MARRVEL helps to facilitate analysis of human genes and variants by cross-disciplinary integration of 18 million records so we can speed up the discovery process through computation,» Liu said.

With the statistical power of 2,000 samples (half in a discovery set, half in a validation set), they were able to search for both cis - regulatory (variants affecting nearby genes) and trans - regulatory (variants affecting distant genes) relationships.

Reykjavik, ICELAND, 12 October 2011 — deCODE genetics today announced that it has entered into a research collaboration with Pfizer Inc., the objective of which is to discover sequence variants associated with specific clinical phenotypes related to Systemic Lupus Erythematosis by utilizing deCODE's expertise in gene discovery.

January 15, 2006 In a scientific paper published today a team of scientists from deCODE genetics (Nasdaq: DCGN) and colleagues report the discovery of a variant in a gene on chromosome 10 that represents the most significant genetic risk factor for type 2 diabetes...

We report the integration of transcriptome sequencing (RNA - seq), which surveys all mRNAs to reveal functional impacts of variants at the transcription level, into the gene discovery framework for a unique human disease, microcephaly - micromelia syndrome (MMS).

deCODE discovered the first variant, a SNP called rs 401681, in its gene discovery work on basal cell carcinoma (BCC), a common form of skin cancer.

This program has resulted in the discovery of unique variants in environmentally responsive genes, the development of a number of resources, and capacity building in the environmental epidemiology communities in order to incorporate gene - environment hypotheses and tools into human population - based studies on a number of environmentally relevant diseases.