Sentences with phrase «discovery of new genes»

The discovery of new genes involved in these repair mechanisms is very important in order to understand the development of these tumours and delve more deeply into their therapeutic vulnerabilities.

With every passing month now, scientists announce the discovery of new genes and gene neighborhoods that can be associated with obesity.

With new tests to identify women who are at heightened risk of breast cancer, new drugs aimed at preventing allergies, and the discovery of new genes that are key to the progression of conditions like Alzheimer's - to give just three examples - we are at the dawn of a whole new era:

This massive dataset is a powerful resource for understanding natural genetic variation in rice as well as for large - scale discovery of new genes associated with economically important traits.

Data access and analysis tools are being made available for the 3K RGP dataset through the International Rice Informatics Consortium (IRIC), which promotes collaboration in bioinformatics analysis of rice data and provides computational tools to facilitate rice improvement via discovery of new gene - trait associations and accelerated breeding.

A European consortium of epilepsy researchers has reported the discovery of a new gene involved in severe childhood epilepsy.

«This led us to the discovery of a new gene in the biosynthesis of this glycolipid, which we termed lipomannan elongation factor or LmeA,» Rahlwes says.

Data access and analysis tools are being made available for the 3K RGP dataset through the International Rice Informatics Consortium (IRIC), which promotes collaboration in bioinformatics analysis of rice data and provides computational tools to facilitate rice improvement via discovery of new gene - trait associations and accelerated breeding.

Not exact matches

Collectively, this new kind of startup can help drive down the cost of gene therapy discovery for patients.

We've been hearing about better male birth control for years now, but in recent weeks two new promising options have come to light: RISUG (reversible inhibition of sperm under guidance), being developed by an Indian scientist, Sujoy Guh, and the discovery of a gene, Katnal1, critical for sperm production; if scientists can tweak the gene with a pill, sperm production will be stalled.

The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics research).

The discovery of a new mechanism for shutting down imprinted genes also raises many provocative questions, Zhang says.

«But the discovery of this network of genes linked to epilepsy opens avenues for finding new treatments.

This study led to the discovery of 18 new imprinted genes, validated some known genes and resolved the disputed status of some others to provide a gold standard list of 93 imprinted genes in mouse.

«The diagnostics lab Baylor Genetics is one of the pioneers in this new era of clinical genomics - supported medical practice and disease gene discovery research,» Lupski said.

Gene discovery was greatly facilitated by a new exome sequencing technology, which analyzes all protein - coding regions of the genome at once.

The discovery of the master gene that sends them into action promises a host of new treatments for infections, cancer and other diseases.

The study, published in the journal Nature Genetics, uncovered 52 genes for intelligence, of which 40 were completely new discoveries.

A study in the journal Nature reports the discovery of rapid - growth genes in rice varieties that can withstand flooding by quickly rising above the new water line.

Within just three years since the discovery of its gene - editing potential, the new technique Crispr has become the hottest, and most controversial, development in genomics research.

The effort has already had one practical result: the discovery of two new genes for resistance to a race of wheat stem rust to which there is virtually no resistance in wheat.

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

Martens suggests that the discovery of a new type of gene in largely ignored nether regions of DNA means that the secrets of the genome are far from known.

For many molecular biologists, the discovery of the CRISPR - Cas9 system marked a new milestone in research: finally, genomic DNA can be cut with high efficiency and precision, enabling genes to be disabled, modified or re-introduced.

It paves the way to new Stb genes» discoveries and to a better management of this devastating wheat disease.»

The new discoveries pertain to the way several parts of the machinery come together and work in concert to tamp down gene expression.

Additionally, in demonstrating the usefulness of the new method, the discovery paves the way for faster progress toward identifying genes involved in complex mental illnesses such as autism and schizophrenia — as well as potential drugs for such conditions.

There is a new contender in the field of gene discovery, and it's giving knockout mice a run for their money.

Researchers led by Baylor College of Medicine have developed a new computational method to study the function of disease - causing genes, starting with an important new discovery about a gene associated with malaria — one of the biggest global health burdens.

The discovery of the Shell gene and its two naturally occurring mutations highlight new molecular strategies to identify seeds or plantlets that will become high - yielding palms before they are introduced into plantations.

This collection of marine microbial genomic, the first in the world on a global scale, will provide new clues about a reservoir of biodiversity yet to explore, considering that it could imply the discovery of tens of millions of new genes in the coming years.

The discovery that mutations accumulate at steady rates over time in the genes of all lineages of plants and animals has led to new insights into evolution at the molecular and the organismal levels

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.

Their discovery of new cancer genes that cause BCC can pave the way for new treatment methods personalized for each tumor.

In a paper in the high - impact journal Cell Research, published April 4, 2017, researchers at the Hebrew University of Jerusalem report the discovery of an entirely new mechanism through which globin genes are expressed.

The marriage of Professors Capecchi and Smithies» homologous recombination technique with Sir Martin's stem cell discoveries has created the highly versatile new technology of gene targeting.

She identified that specific killing of myeloid cells represents an additional mechanism of suppression mediated by Tr1 cells, and she contributed to the definition of a new protocol for Tr1 cell induction using IL - 10 gene transfer and in the discovery of the biomarkers of Tr1 cells.

Dr. Kanner brings more than 25 years of experience in drug discovery and development and will lead Caribou's research and development of new applications for its gene editing technology.

For discovery of new cancer genes and mutational processes, aggregation of tens of thousands of cancer genomes is needed — we are establishing a virtual marketplace for exchange of genomes and informatics and develop increased functionality through the COSMIC portal.

The goal of the program is to discover gene - based biomarkers that can predict outcomes, estimate treatment toxicities, speed discovery of new drugs and create a model that could be reproduced at academic medical centers across the nation.

Throughout his postdoctoral years, at Memorial Sloane - Kettering Cancer Center, and into his tenure at the University of Michigan, Dr. Al - Hashimi remained steadfast in his determination to solve the problem of how to visualize atomic motion, «to obtain a deeper understanding of gene regulation and to build new technologies for drug discovery and biotechnology.»

Scientists from the University of Chicago and Johns Hopkins University have developed a new technique that promises to significantly enhance the rate of novel - gene discovery, a process that becomes increasingly difficult as the Human Genome Project moves closer to completion.

The result was the discovery of three new mammalian genes - known as sonic, Indian, and desert hedgehog - and the realization that the proteins they coded accounted for a significant proportion of all developmental interactions known to occur in the vertebrate embryo.

To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.

The understanding of the molecular pathways the gene control is crucial to the understanding of the mechanisms of pathogenesis, the discovery of new targets and preclinical human therapeutic applications.

«The discovery of the DMRT3 mutation is an outstanding example of how genetic studies of the evolution in domestic animals can lead to basic new knowledge concerning gene function and important biological mechanisms», states Leif Andersson.

The 2006 Nobel Prize in Physiology or Medicine recognized the discovery RNA interference (RNAi), a basic mechanism of gene regulation that also provides an important new tool for functional genome analysis.

Coupled with a new gene - signature approach, this research project could identify compounds that will ultimately lead to the discovery of new neuropsychiatric drugs.

Awareness about 2 important publications from IMPC consortium 1 - The analysis of IMPC database that uncovers 360 new human disease models has just been published: Meehan et al., (2017) Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.