Sentences with phrase «disease affects all tissues»

Periodontal disease affects the tissues that support and anchor the teeth.

Not exact matches

The disease is characterized by the accumulation of very long chain fatty acids (VLCFA) leading to a neurodegenerative disorder that is chronically debilitating and life - threatening, where the most affected tissues are the myelin in the central nervous system (CNS) and the adrenal cortex.

Moody says she will continue to take a more whole - body systemic approach to understand how dietary patterns can affect the epigenome in different tissues in the body and how that can reduce disease risk.

«How can we promise we will cure something without knowing precisely how tissue and cells work and how they are affected by a disease?

Based on the images, the researchers then began a process of elimination, considering various possible diseases — including gout, osteomyelitis (in which the bone itself is infected), and septic arthritis (in which infected cartilage can also affect bone tissue).

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA - approved treatment that affects 200,000 people per year in the United States.

Previous studies have linked other proteins in this membrane to inherited diseases that affect only some tissues.

The investigators suggest that the premature loss of estrogen caused by the oophorectomy may affect a series of aging mechanisms at the cellular and tissue level across the whole body leading to diseases in multiple systems and organs.

Future studies will focus on using these nanobowls to deliver anle138b to the brain, as well as other diseased tissues and organs affected by toxic amyloid - beta ion channels.

While researching the molecular causes of heart failure and new ways to treat it, a Charité - based working group, led by Prof. Dr. Ulrich Kintscher, found that changes in adipose (fat) tissue lipid metabolism affect disease development.

After image processing, even an area appears that is in transition between healthy and affected tissue: this may give an indication how the disease is spreading in the brain.

Using «Raman» optical technology, scientists of the University of Twente in The Netherlands, can now produce images of brain tissue that is affected by Alzheimer's disease.

Patients with Parkinson's disease, cardiovascular disease, and cystic fibrosis may have something in common: cells in their disease - affected tissues may produce misfolded proteins that are incapable of functioning normally.

SLE is a genetically complex chronic relapsing autoimmune disease characterised by inflammation that may affect different tissues, including the skin, joint linings, lungs, kidneys and other organs.

«A better understanding of how inflammation affects stem cells and other components of tissue will revolutionize our understanding of many diseases, including cancer, and likely lead to novel therapies,» Naik says.

If the infection isn't stopped, it can progress into rheumatic fever — a highly contagious disease that affects more than 400,000 people worldwide each year and leaves survivors with lasting damage to heart valves and other tissue.

Fourth, the finding of intranuclear inclusions in diseased tissues, as well as direct visualization of adenoviral - like particles (TMAdV) in lung alveoli by electron microscopy (Figs. 1D - 2 to 1D - 4), support a primary role for TMAdV in the pathogenesis of tissue injury in affected monkeys.

To confirm the presence of virus in diseased tissues, we examined lung tissue from affected monkeys by transmission electron microscopy, revealing abundant icosahedral particles characteristic of adenovirus filling the alveoli (Fig. 1D - 4).

The results showed significant disease improvement, primarily by affecting fat tissue.

Multiple sclerosis (MS) is among the most common neurological diseases in young adults, affecting 350 000 individuals in the United States and 2 million worldwide.1 Prevailing thought is that MS is an autoimmune disorder whereby an unknown agent or agents triggers a T cell — mediated inflammatory attack, causing demyelination of central nervous system tissue.2

The Division of Pulmonary Medicine deals with the breath of life in all its aspects: control of breathing; sleep disorders; obstruction to airflow in the common diseases of upper and lower airways such as croup, bronchiolitis, asthma, cystic fibrosis, and bronchopulmonary dysplasia; restriction to lung function from disorders affecting the chest wall, the musculature, the nervous system, or lung tissue itself; congenital anomalies; accidents such as inhalation of foreign bodies, hydrocarbons, or toxic gases; secondary effects of non-pulmonary system disorders such as gastrointestinal reflux, myopathy, or cardiac dysfunction; disease of the upper respiratory tract including rhinitis and sinusitis; and so on.

TNGB collects, stores and distributes high quality biological materials (nucleic acids, cell lines and tissue samples) linked to relevant clinical and genetic data from patients affected by inherited diseases.

To better understand this complex tissues and its functions — and the diseases that affect it — a multicenter team led by researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital has released a census of the cells that make up the lining of the small intestine, using gene expression profiles of more than 53,000 individual cells from the mouse gut or gut organoid models.

The provided information has been manually curated and can be searched and sorted by various criteria: disease, affected organ / tissue, product specifications, sponsorship or phase of development.

The researchers, led by Richard Proia, compared the affected organoids with tissue from a deceased patient and with organoids with the disease mutation corrected by genome editing.

Liposuction did not significantly alter the insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter plasma concentrations of C - reactive protein, interleukin - 6, tumor necrosis factor alpha, and adiponectin; and did not significantly affect other risk factors for coronary heart disease (blood pressure and plasma glucose, insulin, and lipid concentrations) in either group.

As the disease worsens it can lead to tissue damage, ulceration and gangrene, and in extreme cases may require the amputation of the affected limb.

Aberrant regulation of the epigenetic information results in changes in cell fate decisions, thereby affecting development and tissue homeostasis, and ultimately leading to disease, such as cancer.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

«GTEx will begin to provide researchers with a comprehensive view of genetic variation and a more precise understanding of how it affects genes critical to the normal function of tissues and organs,» said NIH Director Francis S. Collins, M.D., Ph.D. «This resource will add a new dimension to our understanding of human biology and the mechanisms that lead to disease.»

This makes room for the regeneration of new, healthier cells and tissues, which affects longevity and helps reverse diseases of all kinds.

The inflammatory autoimmune disease that affects multiple organs and connective tissue in the body including the heart, brain, lungs, joints, blood vessels, skin and kidneys among others is called Systemic Lupus Erythematosus (SLE).

Well, for periodontal disease, affecting the tissues surrounding the teeth, like gingivitis (gum disease), one of the leading causes of tooth loss, plant - based diets should be protective.

This is important because an autoimmune disease destroys the mitochondria in the affected cells, thus causing tissue destruction, and glutathione protects these mitochondria.

Inflammation is a background problem in other conditions that affect fertility too, such as endometriosis, fibroids, infection (such as the scar tissue of pelvic inflammatory disease), and the insulin block of polycystic ovary syndrome.

19 Ways to Heal Systemic Lupus Naturally The inflammatory autoimmune disease that affects multiple organs and connective tissue in the body including the heart, brain, lungs, joints, blood vessels, skin... Read More

The standard approach to autoimmune disease, the occurrence rate of which far surpasses that of cancer and heart disease combined, is to wait until its advanced enough to either surgically remove the affected tissue or administer severe immune - suppressing drugs.

Crohn's disease may also cause sores, or ulcers, which tunnel through the affected area into surrounding tissues such as the bladder, skin or vagina.

Endometriosis is one of the most common gynecological problems affecting an estimated 5.5 million women in North America, but this condition may occur at a subclinical level in half of all women following the Western diet, as discovered by autopsy.1 This disease occurs when the endometrial tissues lining the inside of the uterus spread outside of the uterus and become attached to the ovaries, fallopian tubes, the bowels and other internal abdominal parts.

According to the National Osteoporosis Foundation: «Osteoporosis, or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures, especially of the hip, spine and wrist, although any bone can be affected.

Because the antibodies are able to get into the affected tissue to attack the infectious agent (for example the saprophyte bacteria found in Crohn's disease), camel milk can help someone heal in ways not seen through any other intervention — dietary or otherwise.

Triggers that affect the immune system's response to certain substances may cause the body to react slower than normal, or over-react where the body attacks and damages its own tissues (autoimmune disease).

There's increasing recognition in the medical community that some individuals who don't have overt celiac disease may still have a sensitivity to gluten, and this can affect various tissue systems in the body, manifesting in ways as diverse as ataxia, anxiety, depression, fatigue, brain fog, headache, schizophrenia, psoriasis, dermatitis, inflammatory bowel disease, acid reflux, and autoimmune conditions (15, 16, 17).

There are more than 100 autoimmune diseases that can affect almost every organ and tissue in the human body.

A veterinary ophthalmologist is a doctor who specializes in diseases that affect the health of your pet's eye, its surrounding tissues and structures, and your pet's vision.

Consequently, despite the fact that it can not identify the «carrier» status, examination of tissues obtained by means of a liver biopsy still remains the method for positively diagnosing the disease, i.e. of identifying affected dogs.

Feline heartworm disease differs from the canine version in that in cats it affects primarily the lungs and, to a lesser extent, other soft tissues and thus is not really a «heart» disease.

Instead, it serves as the catchall category that doctors give to similar joint pain and problems from the more than 100 different categories of conditions or disease that affect the joints and surrounding tissues.

Selective extraction of those affected teeth may be required to allow more space between the teeth, remove the teeth or soft tissue trauma which will decrease any oral pain present and remove further trauma and help decrease the progression of periodontal disease.

Gum surgery and tissue regeneration surgery can be performed to save teeth affected with advanced periodontal disease.