Sentences with phrase «disease affects human»

A major challenge has been to find a way to better understand the way the disease affects human nerve cells.

Malaria is the most significant parasitic disease affecting humans, with 212 million cases and 429,000 deaths in 20151, and resistance to existing drugs endangers the global malaria elimination campaign.

Although Batten disease affects humans, it also occurs naturally in sheep.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

CAHFS serves the people of California by safeguarding the public health with rapid and reliable diagnoses for animal diseases affecting humans.

I knew Lyme disease affected humans but I hadn't thought that my dog could not only get it, but also carry the tick.

We are one of very few cat shelters that house leukemia and FIV - positive cats (neither disease affects humans or other animal species).

Not exact matches

The research was conducted by dozens of international health and environmental experts and incorporates data from the ambitious Global Burden of Disease project, which highlighted how smoking, blood pressure, poor diet, and environmental factors affect human health earlier this year.

As in a human body, when an organ becomes diseased or infected, the whole body is affected, so it is in Christ's body.

Contact with live poultry infected with H7N9 flu appears to be the main means of transmission of this disease to humans, which has affected over 200 people since last spring, killing over 50.

Chronic wasting disease (CWD)-- an infectious disease caused by prions — affects North American elk and deer, but has not been observed in humans.

Since pseudouridine modifications may affect various RNA molecules in different types of normal and malignant cells, «our discoveries pave the way for future avenues of research aimed at exploring the role of pseudouridine in human development disease,» concludes Cristian Bellodi.

The newly identified gene affects accumulation of amyloid - beta, a protein believed to be one of the main causes of the damage that underpins this brain disease in humans.

It is important for NASA to learn how bacterial communities that play roles in human health and disease are affected by spaceflight.

It is unclear how this would translate to people, says Rich, as the disease affects mice differently to humans.

Although researchers do not yet know the biological significance of these discoveries, they say that fully cataloguing the genome may help them understand how genetic variations affect the risk of contracting diseases such as cancer as well as how humans grow from a single - celled embryo into an adult.

The loss of a single gene in mice can affect social behavior and impair their brains» ability to filter out distractions — both characteristics of several neurological diseases in humans.

The open - access, cloud - based 99 Lives database will be used to research both feline diseases and some human ailments, including diabetes, which affects cats similarly — and for which we share risk factors such as a sedentary lifestyle.

The Duke medical researchers and ecologists who have joined that project hope to identify which species flourish in early stages of the human microbiome, how they are influenced by the consumption of breast milk, and what role they play in critical diseases affecting infants as well as in chronic diseases that occur later in life.

«If lowering of LDL cholesterol affects atherosclerosis in humans in the same way, our observations mean that clinically advanced plaques could be prevented if cholesterol - lowering treatments are administered early enough in individuals with increased risk of cardiovascular disease.

Sporadic CJD is the most common human prion disease, affecting about one in one million people annually worldwide.

Several species of protozoa reside in the human gut, and some of them are prevalent in patients with gastrointestinal disease, suggesting that similar host - parasite interactions could affect human health.

«This study allowed us to utilize all our tools — and even though this virus does not appear to affect mammals, we are continuing to refine those tools so we can be better prepared for the next outbreak of disease that could have an impact on human health.»

A research team at The University of Texas at El Paso is one step closer to developing an effective human vaccine for cutaneous leishmaniasis, a tropical disease found in Texas and Oklahoma, and affecting some U.S. troops stationed in Afghanistan and Iraq.

New, sophisticated gene sequencing techniques are leading to an increasing understanding of the causes of genetic disease, and can help parents with affected children make informed reproductive choices, the annual conference of the European Society of Human Genetics will hear.

Their findings, which have been published online in The Journal of Experimental Medicine, expand the type of gut - resident microorganism that can affect the health of their host and suggest that related parasites may cause gastrointestinal disease in humans.

The researchers from the University's Institute of Infection and Global Health ranked the top 100 pathogens affecting humans and the top 100 affecting domestic animals using a system which, they believe, will help governments across the continent plan for risks associated with the spread of infectious diseases, including as a result of climate change, and for biosecurity.

Scientists say that horses affected by the disease — called equine grass sickness — could also hold clues to human conditions.

Like humans, songbirds such as zebra finches (above) can learn vocalizations, and this similarity suggests they could serve as models for research on Huntington's disease and other neurodegenerative disorders that affect speech and vocalization.

The findings, published in the journal Nature, explain why the human genome is so difficult to decipher — and contribute to the further understanding of how genetic differences affect the risk of developing diseases on an individual level.

Steve: Sure and I mean, even if the disease never jumps to humans, if you have a global pandemic just affecting poultry, that's hundreds of billions of dollars in economic losses.

Human diseases that include dyskeratosis congenita, aplastic anemia, and idiopathic pulmonary fibrosis have been genetically linked to mutations that negatively affect telomerase activity and / or accelerate the loss of telomere length.

The teams» three papers, each on Nordic dogs (Swedish Vallhund and Norwegian Elkhound) and each addressing blinding ocular diseases affecting both dogs and people, identified genes causing retinal disease and glaucoma, which may lead to gene therapies for dogs and humans.

«However, except alveolar inflammation and dental caries, the «individual G61» was not affected by any of these diseases — a female skeleton from the Neolithic graveyard of Stuttgart - Mühlhausen,» says Dr. Heike Scherf of the Senckenberg Center for Human Evolution and Paleoenvironment at the University of Tübingen.

We are already widening the application of multivariate analysis to other diseases which commonly affect our pets, and subsequently, this work could also have benefits to human health.»

«It's a bit like human disease but in plants, to understand the pathogen and its interaction with the plant allows to develop a functional cure to treat the affected plants» emphasizes the specialist in plant genomics.

By examining brain regions most affected by Alzheimer's disease pathology in humans, the group demonstrated that amyloid beta plaques and blood vessels were present in all 20 aged chimpanzee brains.

Tomas Marques - Bonet of the Universitat Pompeu Fabra noted that studying gene flow between ancient humans such as Neanderthals, Denisovans and the ancestors of modern humans has revealed numerous genes under selection that affect disease and an individual's traits.

«The parts of the human genome linked to complex diseases such as heart disease, cancer and neurological disorders can often be far away from the genes they regulate, so it can be dificult to figure out which gene is being affected and ultimately causing the disease.»

He added that the existence of episodic memory in lower animals has implications for research on human diseases that affect memory, including Alzheimer's, Parkinson's and Huntington's diseases, since the majority of research on the brain — and the drugs used to treat memory diseases and dementia — start out based on insights into how the brain works in rats.

In recent years, the study of human biology has been shaken up by discoveries of how the bacteria that live in the gut, the so - called microbiome, affect metabolism, the immune system, and disease progression.

They warn that more frequent and more severe natural disasters, instability in food and water supply, the spread of infectious disease, and forced migration «are already affecting human health and provide a glimpse of the near future.»

«Many mitochondrial diseases affect more than one system in the human body,» said Kateryna Makova, professor of biology and one of the study's primary investigators.

Instead, the hardy little bird became a pest by eating crops, displacing some native birds, and harassing others, carrying 29 diseases that affect humans and domestic animals.

Similar to Cushing's disease in humans but affecting a different area of the pituitary gland, PPID is associated with elevated levels of hormones in the blood.

Professor Sinclair said: «It is well established that prior to conception and in the early stages of pregnancy during natural or assisted reproduction subtle chemical changes can affect the human genome leading to development and late - onset chronic diseases.

«Our findings also have important implications for mitochondrial diseases in humans, because this research significantly advances our understanding of how mitochondrial DNA mutations affect individuals and populations, and provides a potential mechanism to explain how different genetic variants may affect health,» Dr Rollins said.

The new Mount Sinai study reveals how loss of a protein called Sirtuin1 (SIRT1) affects the ability of blood stem cells to regenerate normally, at least in mouse models of human disease.

So far, scientists have found that different populations of living humans have inherited the Neandertal version of genes that cause diabetes, lupus, and Crohn's disease; alter immune function; and affect the function of the protein keratin in skin, nails, and hair.

In today's issue of Science Translational Medicine, he and his colleagues present a more efficient way of finding such new uses for old drugs: by bringing together data on how diseases and drugs affect the activity of the roughly 30,000 genes in a human cell.