Sentences with phrase «disease are manifested»

Besides the dog's general state of health, the most common symptoms of this disease are manifested on a neuromuscular, dermatological, cardiovascular, reproductive and ocular level.

«Many retinal diseases are manifested by the degeneration of photoreceptor cells.»

Functional changes occur long before disease is manifested, so functional testing becomes an early warning test for disease which is ideal for prevention - oriented physicians and patients concerned about finding the root cause of their problem.

Data on how these diseases are manifesting in children and teenagers is also becoming more available.

Not exact matches

He also said that Theranos is at the forefront of a paradigm shift in health care, where the emphasis is moving from treating symptoms once a disease has manifested to stopping the illness before traditional symptoms are necessarily displayed.

In his essay, The Gospel and Culture, Voegelin explains that this deculturation doesn't manifest itself as an ideology, or as a «post-Christian» or «postmodern» age proudly positing a «new» system or a unique differentiation of myth, philosophy, or revelation that will «save» man, but rather it is a psychopathology, a disease of the mind, that reveals itself in second realities, egophanic revolt, and a host of similar disorders.

In a way, but we've seen that cancer can manifest itself without being passed genetically, so even if we were to kill off everyone with cancer it still wouldn't completely erradicate the disease.

By then we had been, at most, a couple of hours in Africa, and it seemed unlikely that a tropical disease would manifest itself that rapidly.

The sick did not have to wait for the consummation of the Kingdom before God's victory over disease could be manifested in them.

For >> > the diseases are known to be demons, after having been invited into someone and overcoming his spirit, they manifest >> > themselves in the flesh.»

While there are several ways this may manifest, the most common ways are celiac disease and non-celiac gluten sensitivity (NCGS).

While symptoms of this disease are usually manifested in extremities, they may also appear in your nipples when you breastfeed.

When, down the road, those policies manifest themselves in the form of obesity - related diseases and shorter lifespans for those children, I won't be as generous as Mr. Miller in handing out pardons.

Children have many more years in future life than we adults, and if they are exposed to asbestos, for example, they've got five, six, seven, or eight decades to manifest any disease.

Still's disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen.

Researchers are far from a complete understanding of what causes schizophrenia and how it affects the brain, and some psychiatrists contend that treating a patient for a disease not yet manifest is a clear violation of a basic tenet of medicine: to do no harm.

After Grace's juvenile diabetes was diagnosed in 1978, Anne took it on herself to learn all she could about the disease, and to become something of an expert in the various ways it manifested itself in Grace.

From these findings, it was suggested that patients manifested conditions similar to a genetic disease called Brugada syndrome, which led to fatal heart arrhythmia.

This group's achievements clarified the neural basis of size constancy and are expected to be helpful in improving 3D image - recognition techniques and understanding causes of diseases manifesting size perception disorder.

Our studies reveal that AHR is a novel target for treatment of this disease and potentially other diseases that manifest with excessive scarring,» explained lead investigator Richard P. Phipps, PhD, of the Department of Environmental Medicine and Flaum Eye Institute of the School of Medicine and Dentistry of the University of Rochester (Rochester, New York).

«Alzheimer's disease may be more prevalent, manifest itself differently among african americans.»

Accumulating evidence suggests that changes in the brain can be detected years before the disease manifests clinically.

Contact with such bodily fluids is the way the disease spreads from person to person, with symptoms of infection taking two to 21 days to manifest themselves.

This study was the first to show that astrocytes in patients with Alzheimer's disease manifest many pathological changes typical of AD.

Poertner's former tendency to take a nosedive into his pie is a classic sign of the disease, but the condition often manifests in lesser - known symptoms like paralysis, hallucinations, or «automatic behavior,» in which a person appears to be functioning normally but has no awareness of what he or she is doing.

HD is a fatal, inherited neurological disease that usually manifests between 30 and 50 years of age.

They add that their results suggest that glomerular disease during childhood may initiate kidney injury that manifests in adulthood, well before sufficient loss of excretory kidney function can be measured with standard laboratory tests, such that the first manifestation may be adult hypertension.

The new study is based on the development of mouse models manifesting the disease that causes megalencephaly, spasticity and ataxia in humans.

The findings suggest that cardiovascular diseases also may manifest differently in women and men, which ultimately could affect how they should be diagnosed and treated.

Children have many more years in future life than we adults, and if they are exposed to asbestos, for example, they've got seven or eight decades to manifest any disease.

Single parents, however, may struggle more to keep things together, and this may be impacting children in ways that later manifest as adult onset diseases.»

[T] here are two enormous pitfalls with using symptoms to define Alzheimer's disease; they are neither sensitive nor specific for the neuropathologic changes that define the disease, and they can not identify individuals who have biological evidence of the disease but do not (yet) manifest signs or symptoms.

The most common mutation associated with familial amyloidotic polyneuropathy is V30M; in addition to polyneuropathy, cardiac involvement can be manifested early as conduction disturbances in patients with the V30M mutation and as cardiomyopathy in some patients with the V30M mutation who have advanced disease and in patients with familial amyloidotic polyneuropathy with other mutations.12, 13 The predominant mutation associated with familial amyloidotic cardiomyopathy is V122I; patients with this mutation are susceptible to isolated cardiac involvement and usually do not have polyneuropathy.9 Most patients are heterozygous for the TTR mutations, and the amyloid deposits consist of mutant and nonmutant transthyretin.14, 15

Cancer — now the second leading cause of death in the United States after heart disease — manifests when certain genes are missing or mutated.

Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley.

Progression of chronic kidney disease associated with progressive fibrosis and impaired tubular epithelial regeneration is still an unmet biomedical challenge, because once chronic lesions have manifested, no effective therapies are available as of yet for clinical use.

Importantly, only approximately one ‐ quarter of individuals with the mutations manifest the disease; this incomplete penetrance is also likely a consequence of the effects of disease ‐ modifying genes, environmental influences, or both in a given individual.

«So, the second aim of the study is to try to identify genetic markers that might influence how a disease manifests in a family with a known genetic condition.»

Because the immune system only manifests its potential when challenged, many forms of infectious and inflammatory diseases will be analyzed to assess the states that immunocytes can be pushed to adopt.

The frequency of pathogenic genomes in an individual can be examined through sequencing mitochondrial DNA at high depth, thus determining whether a threshold has been reached where disease has become manifest.

In SMA, we don't test routinely for the gene mutation before the disease manifests, because there is no treatment.

Once a critical number of these «dopaminergic» SNc neurons are lost, the unbalanced firing of those neurons begins to manifest itself in the main motion - related symptoms of the disease.

As DNA damage accumulates with age, persistent DDR - mediated release of SASP factors could be associated with degenerative changes that manifest with old age; in support, several SASP factors are considered amongst the most reliable biomarkers for age - related diseases.

But there's another group of PD symptoms, termed the «non-motor symptoms» (NMS) of PD, that gets far less attention, even though NMS begin to manifest earlier in the disease, are harder to treat with current therapies, and include some of the most crippling features of living with the later stages of PD.

The research suggests that cognitive abnormalities are fundamental in schizophrenia, yet outward signs of the disease only manifest in a subset of carriers of the mutations.

It may be that, most likely, 5 of the therapies will impact health to nullify many disease but will not change the «aging» process (the one that is disconnected from telomeres but related with epigenetics) and 2 last therapies will be of intrinsic aging, of which one could end up not doing anything but remain a mitochondrial improvement manifesting as removal of mitopathies (such as MELAS) but would not alter the course of aging (such as the seperate epigenetic aging going on).

Gene - deficient mice also exhibit signs of spontaneous inflammatory disease, leading to the hypothesis that 4 - 1BB / 4 - 1BBL interactions also play major regulatory roles which might be manifest at the level of Treg or regulatory APC that promote Treg activity.

What is particularly interesting is that AGEs have been shown to induce premature cellular senescence, suggesting that high glucose levels associated with diabetes likely accelerates ageing in other tissues that consequently manifest as disease.

A disease which manifests when the dopamine - producing nerve cells in the brain are damaged and thus produce less and less of this important chemical.

These off - target effects may actually be beneficial in treating IBD, primary sclerosing cholangitis, primary sclerosing cholangitis / IBD - related CRC, and asthma, whereby a multitude of abnormal signaling involving inflammation, oxidative damage, DNA damage, and apoptotic abnormalities exists to manifest itself into a diseased state.