Sentences with phrase «disease at»

Seven of the eight patients treated had active disease at the time of T - cell infusion.
Sex hormones may be a key to explain these differences in men and women, generally suggesting that women are protected by estrogens, hindering the progression of nondiabetic renal disease at least before menopause (333).
A healthy immune system does a truly remarkable job of fighting illness and keeping disease at bay.
Listen in as Dr. Wallace Crandall, Director of the Center for Pediatric and Adolescent Inflammatory Bowel Disease at Nationwide, talks more about living with irritable bowel disease.
She decided Doug Golenbock's lab in the Division of Infectious Disease at the University of Massachusetts Medical School was the place to be, and arrived in the United States one day before 9/11.
11/24/2008 Robert Malinow Named First Shiley - Marcos Endowed Chair in Alzheimer's Disease at UC San Diego Robert Malinow, M.D., Ph.D., professor of neurosciences at the University of California, San Diego School of Medicine, has been named the first recipient of the Shiley - Marcos Endowed Chair in Alzheimer's Disease Research in Honor of Dr. Leon Thal.
[1] The inferior outcomes may be related to the generally more advanced disease at time of diagnosis, anatomic factors complicating complete resection, the rich lymphovascular supply of the mucosal surfaces, and other biological factors.
Dr Nathalie MacDermott: I am doing research into Ebola virus disease at Imperial College London funded by the Wellcome Trust ISSF scheme and the Institute of Global Health Innovation.
But some researchers doubt that self - directed antibodies cause the disease at all.
Of these patients, 1 achieved a durable complete response (95 weeks), 1 achieved a durable partial response (53 weeks), 1 had a transient partial response, and 3 had stable disease at the conclusion of the trial.
Prof John Hardy, Chair of Molecular Biology of Neurological Disease at the Institute of Neurology, UCL
«It is important to note that the real - time quantitative PCR method that was used for MRD measurement is designed to optimally detect disease between 0.01 % and 1 % and may therefore not give an exact measurement of disease at higher levels,» the researchers wrote.
The MBC Project plans to expand its inquiries beyond extraordinary responders to look at patients who have advanced disease at diagnosis, young people with mets and MBC in understudied populations.
A Boston family are in a race against time to raise money for research to help save their son's life, after he was diagnosed with an extremely rare genetic disease at just six months old.
Ann Arbor, MI — Scientists at the University of Michigan have shown that their new metabolic imaging instrument can accurately detect eye disease at a very early stage.
Patients can be diagnosed with metastatic disease at the time of their breast cancer diagnosis or after a period of time has elapsed since their initial early breast cancer was treated.
The group also studies genomic features related to disease at different cellular levels.
What's more is that they detected the disease at early stages in the brains of babies that are less than a year old.
I am also undertaking a PhD in Ebola virus disease at Imperial College London funded by the Wellcome Trust.»
«We see this atlas providing a foundation for investigating many different questions about the pathology in the gut, effects of drug - induced gut toxicities and for identifying and examining important cells, interactions, and biomarkers,» said Xavier, who is also chief of gastroenterology and director of the Center for the Study of Inflammatory Bowel Disease at MGH.
Study coauthors Rammohan Rao of the Buck Institute for Research on Aging and Dale Bredesen of the Buck Institute and UCLA «have provided evidence for a novel — in fact, radical — idea: that ApoE somehow gains access to the nucleosol and acts as a conventional transcription factor, influencing the expression of a large number of genes,» Steven Barger, who studies neurodegenerative disease at the University of Arkansas for Medical Sciences and was not involved in the study, wrote in an email to The Scientist.
Though trastuzumab and pertuzumab have increased response rates and improved outcomes in HER2 - positive breast cancer, 30 % to 40 % of early - stage patients treated in the neoadjuvant setting will have residual disease at the time of surgery.
«SMA is a grave and life - threatening condition, but it is the genetic disorder that is most promising for therapeutic target identification,» said Darryl C. De Vivo, MD, Sidney Carter Professor of Neurology and Pediatrics, and Co-Director of the Center for Motor Neuron Biology and Disease at Columbia University Medical Center.
He held clinical and research fellowships in pulmonary disease at the University of California, San Francisco, and did postgraduate research in physiology and cell biology at the University of Texas, Houston.
«We know that antibiotics are major risk factors for C. diff infection because they alter the gut microbiota, or composition of bacteria in the gut, by eliminating the bacteria that are normally there,» says Casey Theriot, assistant professor of infectious disease at NC State and corresponding author of a paper describing the research.
Dr. Grier received his MD from the University of Pennsylvania in 1976, and then trained in pediatrics, internal medicine, and infectious disease at the University of North Carolina.
Results were particularly striking in mice engineered to develop Alzheimer's disease at about five months of age.
Sanford Research has sought to establish a core of scientists that are studying disease at a fundamental level with the expectation that these current efforts will pay off in the future by advancing disease therapy and prevention.
Isaiah Mansour, an undergraduate at the University of Maine, talks about how a Maine INBRE course on the molecular mechanisms of human disease at the MDI Biological Laboratory changed his life.
He completed an internship and residency in internal medicine at Johns Hopkins and a fellowship in cardiovascular disease at Brigham & Women's Hospital and Harvard Medical School.
Stem cells, derived from skin cells donated by people with and without bipolar disorder, allow scientists to study the disease at its most basic level.
Michael J. Fox was diagnosed with young - onset Parkinson's disease at the age of 30 in 1991.
About the Prosigna ® Breast Cancer Prognostic Gene Signature Assay and nCounter ® Dx Analysis System The Prosigna Assay provides a risk category and numerical score for assessment of the risk of distant recurrence of disease at 10 years in postmenopausal women with node - negative (Stage I or II) or node - positive (Stage II), hormone receptor - positive (HR +) breast cancer.
Without extensive immunization, the H1N1 flu is on track to surpass that toll, says Dean Blumberg, associate professor of pediatric infectious disease at the University of California at Davis Children's Hospital.
When the ageing survivors of the Hiroshima and Nagasaki nuclear bombs and the contaminated Mayak workers started to develop cardiovascular disease at above - normal rates, it became clear that radiation does more than just cause cancer.
We hope this research will lead to a reliable way to spot women at a high risk, so they can be monitored to find any signs of the disease at an early stage.»
The observed upward trend in associated infections is likely to continue, and aging water distribution systems might soon be an additional reservoir of costly multidrug resistance,» said lead study author Elena Naumova, Ph.D., professor at the Friedman School and Director of the Initiative for the Forecasting and Modeling of Infectious Disease at Tufts University.
In most families, the children were affected by the disease at a younger age, but there were no indications that the disease was progressing more quickly.
«By understanding the oxytocin system's dual role in triggering or reducing anxiety, depending on the social context, we can optimize oxytocin treatments that improve well - being instead of triggering negative reactions,» said Jelena Radulovic, the senior author of the study and the Dunbar Professsor of Bipolar Disease at Northwestern University Feinberg School of Medicine.
The findings bolster the predominant hypothesis that amyloid accumulation is the primary culprit in Alzheimer's disease, says Alison Goate, a geneticist who studies Alzheimer's disease at Washington University in St. Louis.
What is the latest biological stage of Alzheimer's disease at which secretase inhibition slows progression?
«The ability to identify, characterize and validate gene targets that strongly associate or correlate with disease development or metastasis will facilitate early detection and appropriate treatments to tackle the disease at an early stage or before metastasis occurs.»
The treatment didn't save every child: a 5 - month - old and an 11 - month - old died of respiratory infections, and a 1 - year - old died from asphyxiation; another infant died of the disease at nearly 7 months old.
Following the suicide, the FBI released court documents laying out some of the evidence linking the anthrax spores found in the letters to Ivins's lab at the U.S. Army Medical Institute for Infectious Disease at Fort Detrick, Maryland.
Anne Tybjærg - Hansen, who studies genetics and heart disease at Copenhagen University Hospital in Denmark, says the study convincingly demonstrates a link between this particular APOC3 mutation and how the body handles triglycerides.
It will include 300 adults recently diagnosed with the disease at 14 participating care sites throughout the country.
Two other monkeys who were given vaccinia did better, as expected, developing no disease at all.
This Purkinje neuron was derived from patients with tuberous sclerosis and model properties of the disease at the cellular and molecular level.
The idea had its skeptics, but Hood viewed the effort as crucial to creating information - based medicine and, ultimately, treating disease at the genetic level.
Seventy - five percent of these cases are classified as high grade serous type, and they show more advanced disease at diagnosis and are more aggressive.
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