But while this approach is good at diagnosing
the disease at later stages, it can miss the disease early on when antibody levels are low.
The detection of melanoma at its most curable stages can result in decades of high - quality life saved, versus the treatment of this terrible
disease at late stages, which offers several months of life extension, at best.»
Not exact matches
Radiologists came from across the hospital to peer
at the results, disbelieving: A perfectly healthy 21 - year - old nonsmoker with no family history of the
disease had lung cancer, which three days
later would be diagnosed as
stage IV, the most advanced form.
Rather than looking
at what distinguished two forms of retinitis pigmentosa, or RP, a progressive blinding
disease, they looked for what they had in common: specifically, what genes were expressed
at the
later stages of
disease.
However, the researchers found that stopping neurogenesis before the development of seizures had a long - lasting effect, suppressing chronic seizure frequency for nearly one year, even
at a
late stage of the
disease.
«If we could perhaps modulate these pathways and prolong survival of photoreceptor cells, we might be able to delay any further degeneration even when intervening
at these
later stages of
disease.»
«We wanted to identify some potential therapeutic targets that are common not just to one but to multiple forms of retinitis pigmentosa
at late -
stage disease, when it is more likely to be clinically diagnosed in a patient population.»
A drug used to treat men with
late -
stage prostate cancer proved effective in stemming progression of the
disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute
at Oregon Health & Science University (OHSU).
Breast cancer cells that spread to other parts of the body break off and leave the primary tumour
at late stages of
disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found.
Pancreatic cancer is a particularly devastating
disease because of the difficulty of identifying it
at an early
stage, and the difficulty of treating it when discovered
at a
late stage.
«Early
stage disease is curable,» adds co-author Bernadette Cracchiolo, director of gynecologic oncology
at the school, «but
late stage and recurrent
disease have limited treatment options.
In some cases,
late onset of the
disease can also occur if the infection is not detected
at an early
stage or if it is not treated with antibiotics.
The findings may help explain why women with bladder cancer are often diagnosed
at a
later stage in the
disease and have worse mortality than men.
«The dBET1 and the dFKBP12 compounds are presently in a
late stage of lead optimization for therapeutic development in both cancer and non-malignant
diseases,» says Prem Das, PhD, chief research business development officer
at Dana - Farber.
Since many of those patients are likely to be given the drugs
at later stages of their
disease, much of this cost is likely unavoidable, even if it gets delayed.
here is epidemiological evidence that links type B coxsackie virus (CVB) infection with heart
disease, and research published on July 31st in PLOS Pathogens now suggests a mechanism by which early infection impairs the heart's ability to tolerate stress
at later stages of life.
What is the
latest biological
stage of Alzheimer's
disease at which secretase inhibition slows progression?
This poor prognosis is partially due to the fact that most patients are not diagnosed until they are already
at a
late stage of the
disease.
The goal was to investigate the ability of J147 to rescue cognitive impairment
at a
late stage in the
disease as an indicator of its potential to rescue cognitive impairment in humans with AD.
Data presented here demonstrate that J147 has the ability to rescue cognitive deficits when administered
at a
late stage in the
disease.
Results from these behavioral assays show that J147 has the ability to rescue the cognitive decline and disinhibition phenotype associated with AD when administered
at an extremely
late stage in the
disease progression when pathology is already far advanced.
I've been working for the last 5 years in trying to bring image resolution to «in vivo» imaging comparable to microscopy because right now we believe there is a disconnect between the clinical imaging that looks
at very microscopic features of the eye that are informative of the
disease but usually
at very
late stages and the exquisite work that molecular biologists are doing.
Lung cancer is the leading cause of cancer mortality worldwide, suffering from a
late stage of
disease at the time of diagnosis and a paucity of effective therapeutic strategies to treat advanced tumours.
«Much to our surprise, the trial showed that patients receiving standard therapy compared to those receiving cetuximab with standard therapy had no difference in outcomes,» said study author Dr. Steven Alberts, a professor of oncology
at the Mayo Clinic College of Medicine in Rochester, Minn. «It also indicates that
disease in earlier
stages may be different than
diseases in
later stages.»
While different types of cancers have different survival rates, in general, it can be challenging to treat the
disease if it was detected
at this
late stage.
This is despite evidence the drug doesn't work that well,
at least in
later stages of the
disease.
But living against the clock — eating
late at night or working overnight — may set the
stage for weight gain and chronic
disease.
Because neoplasia (cancer) can cause orbital
disease and because
later steps in the diagnostic approach may require general anesthesia, your veterinarian may suggest some preliminary blood tests and a chest radiograph
at this
stage.
If that's the case, then owners of cats with mesothelioma may be
at risk for developing the
disease at some
later stage.
However, over weeks, months or even years, when the cat is in
later stages of the
disease (secondary viremia), the infected cat's health may deteriorate to the point
at which he or she has recurrent illness punctuated with phases of wellness.
Because of their location, oral malignant tumors are often detected
late in the course of the
disease process and have commonly progressed to
Stage II
at the time of diagnosis.
It is always better to prevent a
disease, or to catch it early, than to have to treat it
at a
later stage.
However, due to the fact that the
disease is typically diagnosed
at a
late stage, treatment rarely stops the progression of the
disease, and regression is also untypical.