Sentences with phrase «disease challenge studies»

There are veterinarians that question this protocol for legitimate reasons, such as only one brand of vaccine being tested and the use of titers instead of disease challenge studies.

Not exact matches

A study released in the Archives of Disease in Childhood revealed that breastfeeding may be helpful in improving a child's chances of climbing the social ladder and effectively navigating other challenges that may occur as adults.

The charity said this was «particularly concerning» as most of these experiments studied human diseases which do not exist in non-human primates, such as Parkinson's Disease, and this they suggested «significantly challenges» the validity of the tests.

The challenge aims to get students to cut back on beverages like sweetened tea, soda, sports drinks and others with high sugar content which studies show lead to obesity and higher risks of diabetes and heart disease,

The challenge aims to get students to cut back on beverages like sweetened tea, soda, sports drinks and others with high sugar content which studies show lead to obesity and higher risks of diabetes and heart disease, Mantello said.

Huntington's disease and other inherited brain conditions are challenging to study because it is difficult to obtain samples of neurons from living patients.

These SCARB1 gene variant studies aren't the only ones to challenge the long - held belief that increasing HDL was the key to reducing heart disease risk.

It has been challenging to study liver cirrhosis, also called end - stage liver disease, because most animals used in experiments do not develop the disease.

«Mechanistic finding may help develop treatment for Ice Bucket Challenge disease: Study blames a fault in the cell's machine that cuts and pastes genetic instructions for a deadly motor neuron disease.»

«The challenge that remains is if there are many proteins interacting with the huntingtin protein, we can not easily determine which are relevant for disease and which are not,» said Erich Wanker from Max Delbrück Center for Molecular Medicine and corresponding author of the study.

The mini-brain lasts about a month and it could be used to study a range of challenges in neuroscience including transplanting nerve cells that could help treat Parkinson's disease and studies on how adult nerve stem cells develop.

But the study also highlights the challenge of managing ecosystems, because in this case trying to cut down on Lyme disease by, say, trapping mice could send gypsy moth numbers soaring.

Studying aging and its associated diseases has been challenging because existing vertebrate models (e.g., mice) are relatively long lived, while short - lived invertebrate species (e.g., yeast and worms) lack key features present in humans.

To do this, the research team enrolled 65 healthy volunteers aged 18 to 50 years in the human challenge study — a type of research study in which individuals are exposed to disease - causing pathogens under carefully controlled conditions.

Many of the challenges — and the rewards — stem from the fact that the community of people studying and suffering from these diseases is often quite small.

The study, published in Science Translational Medicine, underscores the importance of human challenge studies, in which volunteers are exposed to disease - causing pathogens under carefully controlled conditions.

«Studying diseases with complex genetics is extremely challenging.

The study's conclusions address a major challenge in current standards of care for prostate cancer: Without knowing a tumor's underlying biology, physicians can not reliably predict which of their patients will develop dangerous forms of the disease.

But a new study by University of Virginia researchers challenges this idea and suggests that axons coordinate each other's destruction, thereby contributing to the degeneration that makes neurological diseases so devastating and permanent.

But studying how the cells of complex tissues like the mammary gland self - organize, make decisions as groups, and break down in disease has been a challenge to researchers.

Chronically - ill cancer patients have different exercise limitations than their healthy counterparts and other concurrent diseases and high symptom burden add challenges in how best to study and implement physical activity programs in lung cancer patients.

The United States has sufficient capacity for treating another outbreak of the Ebola virus, but financial, staffing and resource challenges remain a hurdle for many hospitals and health systems attempting to maintain dedicated treatment centers for highly infectious diseases, according to new study released today.

A new study challenges the widely held view that mice are the main animal reservoir for Lyme disease in the United States.

«This study challenges some of the long - held beliefs about how gastroesophageal reflux damages the esophageal mucosa in patients with gastroesophageal reflux disease,» said first author Dr. Kerry Dunbar, Associate Professor of Internal Medicine and staff physician with the Department of Gastroenterology at the Dallas VA Medical Center.

Stricter safety procedures and new ways to weaken pathogens to reduce their risks are leading investigators in industry, universities, and government to take a new look at human challenge trials, which offer a powerful tool for studying diseases and potential therapies.

«Although this is an important start, we will need to do larger studies to establish whether this therapy can produce important and durable benefits for people suffering from this challenging disease.»

People facing mental health challenges are significantly more likely to have heart disease or stroke, according to a study presented today at the Canadian Cardiovascular Congress.

Even more studies show that people who continue to challenge themselves intellectually have lesser rates of Alzheimer's disease and other forms of dementia and mental decline.

«Alzheimer's disease: Neuronal loss actually very limited: Study challenges current scientific consensus.»

By studying the skeletons of farmers, peasants, monks, and nobles, paleopathologists hope to find out what diseases killed people from medieval times until the present — and how their overall health fluctuated during famine, war, climate change, and other challenges.

The idea that it might be possible to be overweight or obese but not at increased risk of heart disease, otherwise known as the «obesity paradox,» has been challenged by a study of nearly 300,000 people published in in the European Heart Journal today (Friday).

Results of the study, which earlier this year won first prize in the inaugural «PAN Challenge» for research on improving access to critical medications for Americans with chronic and rare diseases, showed that patients in the latter, high - cost group were significantly less likely (45.3 percent vs. 66.9 percent) to have a Part D claim for a TKI prescription within six months of their CML diagnosis, compared to the subsidized, low cost - sharing group.

With the support of the Wellcome Trust, MORU studies and combats some of the most challenging tropical diseases affecting people in the developing world.

Specifically, 1 unit of access comprising a vaccination / challenge study with 3 groups of 6 ferrets (control and 2 vaccine groups), to include vaccination / boost, intra-nasal challenge with influenza virus, monitoring of virus load (nasal washes), disease progression and immune responses (antibody, IFN gamma ELISA and ELISpot).

«Organ - Chips address major challenges in studying the human intestine and intestinal diseases in the lab,» said Geraldine A. Hamilton, PhD, president and chief scientific officer of Emulate and a co-author of the study.

One of the major challenges preventing researchers from efficiently generating and studying these genetic diseases is that they can exist at frequencies as low as one - in - a-thousand, making the task of finding and studying them labor - intensive.

I now find that this broad experience allows me to link ideas and observations together to have better insight into the disease, and enabled me to address technical challenges and limitations using a wide range of tools, some of which have not been applied to studies of neurodegenerative disease.

Right now, there isn't much - published data on CRISPR's use in monkeys, but early results from small studies point to the prospect of a cure for some diseases, and even to certain challenges.

«[These] findings from the most comprehensive large study ever undertaken of the relationship between diet and the risk of developing disease are challenging much of American dietary dogma.»

The mechanisms which impact aging and aging - related diseases are complex and challenging to study.

In a new study published in PLoS Computational Biology, researchers at Maastricht University and the Gladstone Institutes tackled this challenge to improve the integration of disparate sources and types of data and advance scientists» understanding of disease.

Incomplete penetrance, genetic heterogeneity, pleiotropy, and gene - environment interactions are just some of the factors that make even studies of relatively simple genetic diseases challenging.

Karen lost her battle to cancer, a challenging disease she herself studied with meticulous detail.

Genome sequencing has become a powerful tool for studying emerging infectious diseases; however, genome sequencing directly from clinical samples without isolation remains challenging for viruses such as Zika, where metagenomic sequencing methods may generate insufficient numbers of viral reads.

The unit of access comprises a vaccination / challenge study with 3 groups of 6 ferrets (control and 2 vaccine groups), to include intra-nasal challenge with influenza virus, monitoring of virus load (nasal washes), disease progression and immune responses (antibody, IFN gamma ELISA and ELISpot).

She has headed a number of studies on the content and effects of trans fatty acids in America and Israel and has successfully challenged government assertions that dietary animal fat causes cancer and heart disease.

In that study, which included 21 people with celiac disease who consumed the gluten for about three months, two - thirds of the subjects had gluten - induced intestinal damage, but only nine had positive celiac blood tests following their gluten challenges.

Observations from basic research and epidemiologic studies support the hypothesis that the antioxidant vitamin E may reduce the risks of developing cardiovascular disease (CV) and cancer, but findings from randomized trials challenge it.

Wynn, a homeopathic veterinarian, continued: «The results of one well - controlled study suggest that parvovirus nosodes are completely ineffective in preventing parvoviral disease under experimental challenge conditions.

The North Carolina State University (2) published a vaccination protocol in 2001 that «highly recommended» vaccination against distemper with a modified live vaccine but noted that, because some studies indicate that dogs are still protected for five years or more when challenged by the disease, «a booster vaccination of every three years among adult dogs is reasonable.»