Sentences with phrase «disease develop over years»

«For reasons we're still trying to understand... we see single sites of metastatic disease develop over years or, in some cases, decades,» says Swanton.

Not exact matches

Facebook co-founder and chief executive Mark Zuckerberg and wife Dr Priscilla Chan have pledged to invest more than $ 3 billion over the next ten years to develop research technology that can fight and cure diseases globally.

«Over the last four years we built a network in Uganda of over 1,000 sales agents and are on our way to establishing a self - funded system for fighting disease and poverty in the developing woOver the last four years we built a network in Uganda of over 1,000 sales agents and are on our way to establishing a self - funded system for fighting disease and poverty in the developing woover 1,000 sales agents and are on our way to establishing a self - funded system for fighting disease and poverty in the developing world.

The link between eating gluten and developing coronary heart disease was monitored over the 26 - year period.

Approximately 175000 cancer cases are diagnosed annually in children younger than age 15 years worldwide, 1 with an annual increase of around 0.9 % in incidence rate in the developed world, only partly explained by improved diagnosis and reporting.1, 2 Childhood cancer is rare and its survival rate has increased significantly over the years owing to advancement in treatment technologies; however, it is still a leading cause of death among children and adolescents in developed countries, ranking second among children aged 1 to 14 years in the United States, surpassed only by accidents.1, 3 Childhood cancer is also emerging as a major cause of death in the last few years in Asia, Central and South America, Northwest Africa, and the Middle East, where death rates from preventable communicable diseases are declining.2

The period from July through September is when the transmission of the disease appears most common, with persons under 15 years of age and over 50 years at greatest risk of developing severe symptoms of EEE.

Over the past 29 years, TDR has supported scientists both in developed countries DECs to produce new tools and strategies for controlling tropical diseases.

Over the years, Pert's interest in receptors and peptides included efforts to develop peptide - based treatments for HIV, Alzheimers, and other diseases.

Now a study of 10,892 adults over 10 years has found that, in the first six years after giving up, former smokers are 70 per cent more likely than non-smokers to develop the disease.

They found that over a 20 - year period, people with rheumatoid arthritis have a 1 in 4 chance of developing chronic kidney disease, compared with the general population's 1 - in - 5 risk.

Adults who closely followed the Mediterranean diet were 47 percent less likely to develop heart disease over a 10 - year period compared to similar adults who did not closely follow the diet, according to a study to be presented at the American College of Cardiology's 64th Annual Scientific Session in San Diego.

Those who scored in the top - third in terms of adherence to the Mediterranean diet, indicating they closely followed the diet, were 47 percent less likely to develop heart disease over the 10 - year follow - up period as compared to participants who scored in the bottom - third, indicating they did not closely follow the diet.

Over the past few years, Mark Schaller, a psychologist at the University of British Columbia, has been developing an intriguing theory that behavior can be just as effective as microbiology at warding off disease.

Homeless people with mental disease have a greater than double risk of developing serious or fatal cardiovascular disease over 30 years than people of the same age and gender with no risk factors for the disease, new research has found.

Similarly, a 2012 Harvard University study found that men who drank at least four sugar - sweetened beverages per week over a 22 - year period were 20 percent more likely to develop heart disease than those who drank none.

There hasn't been a new drug developed for Chagas disease for over 30 years so it's the significance of the unmet medical need there that drove our focus to our diseases.

Over the past two years Skinner, of Washington State University, showed that as male descendants of these rats aged, they developed sperm deficiencies, infertility, and various other afflictions, from breast tumors to kidney disease.

They included China's ambitious 15 - year plan aimed at understanding the neural basis of cognitive functions while developing the tools to diagnose and treat brain diseases early; it is likely to be funded with $ 1 billion over the first 10 years.

A number of theories have been developed over the years to explain more recent extinctions such as those at the end of the last ice age, including human hunting, climate change, disease, and even a cosmic impact such as an asteroid or comet.

In March the American Journal of Clinical Nutrition published a meta - analysis — which combines data from several studies — that compared the reported daily food intake of nearly 350,000 people against their risk of developing cardiovascular disease over a period of five to 23 years.

Measures taken in developed countries to reduce noncommunicable diseases — the leading causes of death globally — have improved the life expectancy of women aged 50 years and older over the last 20 to 30 years.

Over the course of about a year, his new venture took shape: Perlstein Lab — PLab for short — a for - profit, public - benefit corporation that aims to develop treatments for rare diseases.

By tuning the model to replicate population data, such as the number of people at risk for developing TB and the fraction of TB patients who have drug resistance, the model can predict changes in the TB disease burden — or number of cases — over many years.

Amphotericin B (AmB) is the main active ingredient in the most effective drug used to treat leishmaniasis, a disease which in the Western world mainly affects dogs, but in developing countries affects over 12 million people, with more than 70,000 deaths per year.

A research team has discovered a group of molecules in the blood that they say can predict with 90 % accuracy whether older people will develop Alzheimer's disease over the course of 2 to 3 years.

My goal over the past several years has been to adapt new advanced optical imaging technologies to the study of human diseases, and where we lack tools to study specific aspects of human vision diseases, to develop new ones to fill in the gaps.

In one natural history study of 55 untreated US patients with early Lyme disease associated with erythema migrans, 34 (62 %) developed objective signs of arthritis, 10 (18 %) developed arthralgias without arthritis, but 11 (20 %) remained completely well over a mean follow - up of 6 years [2].

«Using computer modeling he developed over 20 years, Jacobson has found that carbonaceous fuel soot emissions (which lead to respiratory illness, heart disease and asthma) have resulted in 1.5 million premature deaths each year, mostly in the developing world where wood and animal dung are used for cooking.

The number of people in Bangladesh dying from chronic diseases such as cancer, diabetes and hypertension — long considered diseases of the wealthy because the poor didn't tend to live long enough to develop them — increased dramatically among the nation's poorest households over a 24 - year period, suggests new research from the Johns Hopkins Bloomberg School of Public Health

Then the participants will be followed over several years to see if, or when, they develop Parkinson's disease.

There's no cure, and although symptoms develop over years, there is little doctors can do to stop the progression once the disease has taken hold.

Over 17,000 people die each year from the two diseases in the UK, but very little is known about how they develop and why patients respond differently to treatment.

The risk of cardiovascular related illness and death is known to decrease after smoking cessation in patients with coronary heart disease, 40 reducing dramatically over the first three years, 41 but reducing the risk of developing lung cancer after smoking cessation generally takes longer.9 41 This review has found evidence that after lung cancer has been diagnosed, reductions in risk of developing a second primary or recurrence were associated with quitting within seven years, suggesting that, even at this stage, the prognostic outlook can be improved by smoking cessation.

Over the following years, he and his colleagues cloned the HD gene, located its stretch of repeated DNA, showed that the size of that stretch is correlated with age of disease onset and age of death, described how it causes disease, and identified genetic factors that affect how quickly symptoms develop.

Over the 3 - year duration of the study, some of the participants who hadn't been diagnosed with Huntington's disease at the beginning of the study have now developed symptoms of the disease.

In the meanwhile, a big number of studies have shown that consuming a moderate amount of full - fat diary products instead their low - fat versions can reduce the risk of developing heart disease and diabetes, while in healthy people over 60 years of age, a higher cholesterol has been associated with a lower risk of mortality.

MONDAY, November 21, 2011 (Health.com)-- Over the past several years, researchers have noticed an odd pattern in the relationship between body weight and Alzheimer's disease: Middle - aged people have a higher long - term risk of developing the disease if they're overweight or obese, while older people have a lower risk of the disease if they're carrying excess weight.

Over the past several years, researchers have noticed an odd pattern in the relationship between body weight and Alzheimer's disease: Middle - aged people have a higher long - term risk of developing the disease if they're overweight or obese, while older people have a lower risk of the disease if they're carrying excess weight.

Researchers found that the more coffee people downed, the less likely they were to get the disease: Those drinking four cups daily had a 20 percent lower risk of developing malignant melanoma over a 10 - year period than non-coffee drinkers.

The World Health Organization (WHO) reports that over sixteen million deaths occur worldwide each year due to cardiovascular disease, and more than half of those deaths occur in developing countries where plant - based diets high in legumes and starches are eaten by the vast majority of the people.

One large study of middle - age female nurses found that both sleeping too little and too much was linked with higher risks of developing heart disease over a 10 - year period compared with normal sleepers.

One study ran over a course of 30 years which supports that noncoffee drinkers are 5 times more likely to develop Parkinson Disease than coffee drinkers (10).

In the Rotterdam study, those who had the highest intake of Vitamin K2 were 52 % less likely to develop calcification of the arteries, and had a 57 % lower risk of dying from heart disease, over a 7 - 10 year period (9).

Nationally, the researchers» calculations predicted that 14.6 percent of men and 7.5 percent of women will develop heart disease over the next 10 years.

Kidney disease is one more potential complication of poorly controlled diabetes, and, unfortunately, it can develop over a number of years before symptoms show.

Over the last 25 years he has developed innovative methods for healing the mind - body - spirit through eye therapy and provides individuals with natural alternatives for reducing disease and improving vitality.

In short order, however, Bowie's John begins to develop frightening symptoms, aging years every hour, and the erotic tenor of the film shifts rapidly to an extended metaphor for disease, with Deneuve's Miriam presiding over a host of immortal but aged lovers trapped as withered husks in coffins, testament to an addiction that consumed them.

Invested $ 38 million last year in heart and stroke research, including a program that will track the health of more than 10,000 Canadians over several years, to learn why some develop heart disease, stroke and cancer while others don't

Over twenty years later, the number of dogs presenting with this disease prompted the Swedish Kennel Club to become one of the first to develop a program to reduce the incidence of hip dysplasia.

Over the years, since I entered the profession in the early 70's more effective safer vaccines have been developed against these diseases and they have been widely used to a point where most pets have been vaccinated to at least some degree.