Taurine is known to have some preventive effects on type 2 diabetes and its complications, but can it also prevent the kidney
disease diabetic nephropathy?
Not exact matches
In both cases, left untreated, the extra glucose in the blood can cause blindness, cardiovascular
disease,
diabetic nephropathy,
diabetic neuropathy and death.
Zhang's team focused on two of them, saxagliptin and sitagliptin, along with an antioxidant supplement called α - lipoic acid, which is used to treat
diabetic nephropathy, a common complication of the
disease.
The compound is now in phase II clinical trials for
diabetic nephropathy and is being explored in other fibrotic
diseases.
In patients with chronic kidney
disease who are not on dialysis, ACEIs and ARBs slow the progression of
diabetic nephropathy and reduce cardiovascular risk.
Major
diabetic complications will be discussed with emphasis on known sexual dimorphism and gender differences will focus on cardiovascular
disease (CVD), cardiomyopathy, and
nephropathy.
In contrast, testosterone accelerates the development of nondiabetic chronic renal
disease, and in streptozotocin - induced
diabetic male rats, decreased testosterone levels and changes of sex hormone levels exacerbated the development of
diabetic nephropathy, showing the importance of sex hormones in pathophysiologic mechanisms behind
disease progression (334).
Renal complications, also known as
diabetic nephropathy, are one of the most life - threatening complications of diabetes that often lead over time to end - stage renal
disease (ESRD).
Also noted by IER studies are an increase in the expression levels of silent mating type information regulation 2 homolog 1 (SIRT1), an NAD + - dependent deacetylase.20 The expression of SIRT1, also increased by prolonged ER in rodents, is linked to the up - regulation of cellular stress resistance and improved outcomes in animal models of metabolic, neurodegenerative and inflammatory
diseases.106, 107These findings have been suggestively accompanied by improvements in resilience to
disease progression in rodent models of Type 1
diabetic nephropathy 20, survival following induced ischaemic injury 21 and a reduction in oxidative stress.105
Kimmelstiel - Wilson
disease (also known as
diabetic nephropathy, or simple kidney
disease) is a kidney
disease that makes blood filtration through the kidneys become more difficult.