Sentences with phrase «disease end points»

Not exact matches

The authors suggest minimal residual disease status may be a marker of long - term survival outcome and the assessment of minimal residual disease status after treatment should be considered as an end - point in clinical trials.

«No significant safety concerns or dose - dependent adverse side effects of AVI - 7288 were reported with respect to any safety end point evaluated,» said Michael Wong, M.D., senior medical director for infectious diseases at Sarepta.

But other scientists have pointed to natural causes, including volcanic eruptions, disease, and climate change at the end of last Ice Age, as the key reasons for these species» demise.

This meeting provides a nexus for diagnostic developers in academia and industry as well as end - users in the pharmaceutical and healthcare sector to gain a comprehensive picture of molecular diagnostics in prenatal, oncology, infectious disease, point - of - care, and liquid biopsy.

Here researchers take a different strategy to the normal approach of painstakingly tracing relationships between proteins in cells, starting at the end point of full blown disease and working backwards one step at a time.

Rethinking the traditional drug development process for rare diseases will be critical, including trial design for small populations, real - world evidence collection, stronger patient engagement for data collection and definition of clinical end - points.

Sheng Ding, a stem cell biologist at the Gladstone Institute of Cardiovascular Disease and the University of California, San Francisco, pointed out that efficiencies are never 100 percent — meaning researchers end up with a heterogeneous culture of reprogrammed and not - so - reprogrammed cells.

In rodents, this has been shown to translate into improvements in clinical end - points such as disease progression.

Dr Dariush Mozaffarian (Harvard Medical School, Boston, MA), who was also not involved with the study, said that heart - disease death, rather than nonfatal heart disease or total cardiovascular disease, is the clinical end point most likely influenced by fish oil.

«Strong evidence indicates that dietary saturated fatty acids (SFA) are positively associated with intermediate markers and end - point health outcomes for two distinct metabolic pathways: 1) increased serum total cholesterol (TC) and LDL cholesterol (LDL - C) and increased risk of cardiovascular disease (CVD) and 2) increased markers of insulin resistance and increased risk of type 2 diabetes (T2D).

The most important point I can make about diabetes, is that since high blood glucose is the end result and primary harmful health consequence of the disease, we need to avoid simple carbohydrates and sugars.

Nearly a quarter of these dogs will end up developing intervertebral disk disease at some point in their life.

Pretty much all cats will end up with kidney disease at some point in their life.

This point is supported by the fact that of the nurses caring for Thomas Eric Duncan, the man who died from Ebola virus disease in Texas in October, only those who cared for him at the end of his life, when the number of virions he was shedding was likely to be very high, became infected.

Pets can end up getting just as sick as human beings, too — dogs have a 25 % chance of developing a tumor at one point in their life, while 10 % of cats develop a Feline Lower Urinary Tract Disease.

Wade ended with a season best 27 points and afterward posted on social media about the special night while mentioning both Oliver and his late agent, Henry Thomas, who died at age 64 in January after suffering from a neuromuscular disease.