Sentences with phrase «disease in a living animal»

«What's impressive is that, unlike in a mouse or rabbit, you can actually see the organism producing disease in the live animal,» said John R. Perfect, M.D., chief of the division of infectious diseases at Duke University School of Medicine.

Not exact matches

The animals were starving, diseased and living in terrible squalor; Elsie and her foal were both very poorly, but thankfully they pulled through.

At certain stressful times in a young animal's life, as when it is weaned from its mother, it becomes particularly susceptible to disease.

«We've known that aging is a major risk factor for most chronic diseases for some time, but recently, we've gained a better understanding of the aging process's basic underpinnings, which has allowed us to extend both life span and health — in animals at least,» says Felipe Sierra, director of the Division of Aging Biology at the National Institute on Aging.

When we suppressed the ALS mutation in the brains of animals, onset of the disease was delayed, the animals lived longer, spinal motor neurons survived longer, and the neuromuscular junctions stayed healthy longer,» said Svendsen, the Kerry and Simone Vickar Family Foundation Distinguished Chair in Regenerative Medicine.

«Understanding the evolution of malaria parasites in bats and other animals, and how they fit into the tree of life, is key to understanding this important human disease.»

Although most animals» cognitive abilities decline late in life, only people seem to develop Alzheimer's disease, which can result in severe dementia symptoms.

«This landmark study draws the conclusion in pre-clinical animal studies that stem cell therapy for disc degenerative disease might be a potentially effective treatment for the very common condition that affects people's quality of life and productivity,» said the senior author, Wenchun Qu, MD, PhD, of the Mayo Clinic in Rochester, Minn..

«The animals — who are housed in unbearably small cages — live with fear, stress, disease, parasites and other physical and psychological hardships...» reports PETA.

After the deadly virus struck in 2002, disease researchers traced it to raccoonlike animals called Himalayan palm civets, which are sold for food in live - animal markets in China.

However, it and other animal groups were less happy with other aspects of the changed directive, especially moves to allow the reuse of animals and the use of nonhuman primates in experiments not directly linked to life - threatening or debilitating diseases.

These relations to the common mosquito live in the tropics and subtropics and transmit diseases dangerous to humans and animals from avian malaria to the West Nile virus.

One of the challenges in fighting infectious disease is that researchers can not watch individual pathogens inside living animals.

Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease - free aging, in animal studies, and even to extend life span in most animal species examined.

The faster speed means it will be possible for the first time to watch disease progression in living animal models at the molecular level.

Animals with gene mutations that significantly alter their circadian rhythms have shorter life spans, and circadian rhythm sleep disorders in humans can have profoundly negative effects, including increased risk for obesity, depression, cardiovascular disease and cancer.

Along with the studies in live animals, the research team also studied human brain tissue from Northwestern's Cognitive Neurology and Alzheimer's Disease Center.

Next - generation sequencing — the ability to sequence millions or billions of small fragments of DNA in parallel — has revolutionized the biological sciences, playing an essential role in everything from locating mutations that cause human disease to determining how a newly discovered animal fits into the tree of life.

Although the bacteria shared common features (most live inside animals and many cause disease), the pattern of species carrying and lacking the gene suggested that the gene had been shuffled horizontally in the family tree, between distantly related species, not passed down from an ancient ancestor.

«We wanted to develop a newborn screen for NPC because we know that the earlier we intervene with investigational treatments in animal models of the disease, the longer the animals live,» said Ory, the Alan A. and Edith L. Wolff Distinguished Professor of Medicine.

Animal safety studies were taking place in parallel with this trial, which is a common practice when studying potentially life threatening diseases to help bring medicines to patients faster.

Basic research involves figuring out how living organisms, from the cellular level up to the whole animal or person, work and also what can go wrong in disease or injury.

Higher temperatures and changes in precipitation can alter the ranges and life cycles of disease - causing pathogens and the animals that carry them.

Microscopic models — half living, half not — may prove more reliable than animals in explaining human disease and testing therapies.

By supporting Directive 2010 / 63 / EU, LERU wishes to call attention to the fundamental importance of the use of animals in research and the vital role it plays in understanding and providing treatment for a range of debilitating and life threatening human diseases such as cancer, primary immunodeficiencies, neuro - degenerative diseases and heart failure.

Dhanansayan «Dhanu» Shanmuganayagam, a nutrition and animal sciences professor in the UW — Madison College of Agricultural and Life Sciences, has spent most of his career using swine to study human diseases, particularly heart disease.

In animals, it has been found that high exposure to this substance cause respiratory tract diseases, decreased life spans and even cancer.

In support of this concept, we have shown that mtDNA mutations accumulate in proportion to life span in several animals, that increasing mitochondrial anti-oxidant defense systems extends lifespan, that ancient human mtDNA variants that modify energy production and oxygen radical production can modulate longevity and risk for neurodegenerative diseases, and that patients with the neurodegenerative disease, Alzheimer Disease, have increased mtDNA mutationIn support of this concept, we have shown that mtDNA mutations accumulate in proportion to life span in several animals, that increasing mitochondrial anti-oxidant defense systems extends lifespan, that ancient human mtDNA variants that modify energy production and oxygen radical production can modulate longevity and risk for neurodegenerative diseases, and that patients with the neurodegenerative disease, Alzheimer Disease, have increased mtDNA mutationin proportion to life span in several animals, that increasing mitochondrial anti-oxidant defense systems extends lifespan, that ancient human mtDNA variants that modify energy production and oxygen radical production can modulate longevity and risk for neurodegenerative diseases, and that patients with the neurodegenerative disease, Alzheimer Disease, have increased mtDNA mutationin several animals, that increasing mitochondrial anti-oxidant defense systems extends lifespan, that ancient human mtDNA variants that modify energy production and oxygen radical production can modulate longevity and risk for neurodegenerative diseases, and that patients with the neurodegenerative disease, Alzheimer Disease, have increased mtDNA mutdisease, Alzheimer Disease, have increased mtDNA mutDisease, have increased mtDNA mutations.

Approximately twenty million pounds of antibiotics are given to animals each year — most to prevent disease and promote growth.27 Antibacterials, topical antimicrobials, and insecticides are also used in the feed, living quarters, and directly on the animals themselves.

There are many factors involved in this seeming decline in health — increases in population, crowding, living in close proximity with animals and the resultant transmission of diseases, but certainly the change in diet was a major factor.

Conventionally raised poultry is contributing to an alarming increase in antibiotic resistant microbes, since these animals are fed large doses of antibiotics regularly to fend off diseases that would otherwise disallow birds to live in cramped, overcrowded conditions.

Living in close proximity to animals has led to some of the most serious infectious diseases we humans have ever encountered, diseases such as smallpox, measles, bird flu, and tuberculosis.

One reason is because the microbes in our gut that live on animal products cause inflammation in our entire system when we consume them; another reason is because the cholesterol and saturated fat in animal products cause many diseases,

For example, a study comparing Jews when they lived in Yemen, whose diets contained fats solely of animal origin, to Yemenite Jews living in Israel, whose diets contained margarine and vegetable oils, revealed little heart disease or diabetes in the former group but high levels of both diseases in the latter.14 (The study also noted that the Yemenite Jews consumed no sugar but those in Israel consumed sugar in amounts equaling 25 - 30 % of total carbohydrate intake.)

Amongst several auxiliary discoveries such as a lack of cancers, zero facial deformation, zero cavities, rugged resistance to disease and joyful exuberance for life... he noted that all of the strongest, healthiest and happiest tribes he studied ate a diet rich in saturated fats from animal meat and organs.

The Maasai, Nomads from Kenya and Tanzania, live on a diet that is very rich on animal meats and fats (proteins) and poor in carbohydrates, but they rarely have any heart - or cardiovascular diseases.

Whereas cortisol may have saved our lives when we lived more connected to our animal natures, this stress hormone is now pulsing through our bodies on a daily basis, causing fatigue and anxiety in the short term, and adrenal burnout (among other diseases) in the long run.

The results in many lab animals are available, longer life (40 %), less cancer, heart disease etc, more neurons, less hypertension and diabetes..

Lessons like raising money for those in need ~ collecting supplies for animals that cant help themselves ~ and assisting children with a fatal disease to live out their dreams.

Our approach to achieving this goal focuses on three objectives: (1) to develop a reliable, predictive panel of biomarkers (including both biological and bio-behavioral measures) that can identify children, youth, and parents showing evidence of toxic stress, and that can be collected in pediatric primary care settings; (2) to conduct basic, animal and human research on critical periods in development and individual differences in stress susceptibility, thereby informing the timing and design of a suite of new interventions that address the roots of stress - related diseases early in the life cycle; and (3) to build a strong, community - based infrastructure through which scientists, practitioners, parents, and community leaders can apply new scientific insights and innovative measures to the development of more effective interventions in the first three postnatal years.

House rabbits are very clean animals and, in general, they manage to carry on relatively disease - free lives.

Additionally, free range enclosures are being built in Tasmania as natural habitats for the animals to live and reproduce, protected from a diseased population.

Clean and sterilize the animal enclosures in order to prevent the spread of communicable diseases and provide a pleasant living environment for the clinic's patients.

While there is no known way to prevent the disease, animals with hypothyroidism benefit from life - long supplementation of the thyroid hormone in pill form and regular veterinary check - ups.

Caused by bacteria which, if left unchecked, form a layer of a sticky residue called plaque over the teeth of an animal, Periodontal disease (PD), will often begin very early in a pet's life.

In one study, 86 per cent of owners of companion animals with heart disease said they would trade the animal's longevity for their quality of life

PATTI DONEGAN»S letter focused on the problem of puppy mills, backyard breeders and dog brokers.Florida Statute 585.195 states each dog offered for sale shall be inoculated against canine disease prior to sale.Florida Statute 823.15 requires sterilization of dogs and cats released from an animal shelter or humane society.The problem in Orange County is the lack of enforcement of these laws, and the need to extend sterilization requirements to back - yard breeders.The public can become involved by encouraging the county commission and city councils to enforce the rules and regulations presently on the books, until a countywide ordinance can be made law that protects the needs of the consumer and the lives of the animals.

Perhaps the biggest con to the FIV vaccination is the notion that if we inject a little of the virus early on in the life of our cats in order to prevent contracting the disease later on, then we run the risk of losing them permanently if they are ever picked up by animal control or a shelter if they wander off.

Puppy mills contribute to pet overpopulation, particularly in urban areas, and are known for their poor living conditions that lead to diseased animals often being sold to unsuspecting pet owners across the country.

Dr. Best's love for ophthalmology initially developed during veterinary school where she was drawn to both the medical and surgical aspects of managing animal eye disease in order to improve her patient's vision and quality of life.