Reports of
disease outbreaks at food processing facilities, food product recalls and related litigation.
In all, 80 percent of corals bleached and more than 40 percent were killed by a combination of bleaching and
disease outbreaks at several sites in the Caribbean.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the
outbreak of
diseases or epidemic or pandemic
outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or
at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
JOHANNESBURG, March 19 - Tiger Brands has closed its factory in Pretoria after listeria was detected
at the plant as South Africa faces the worst global
outbreak of the
disease that has killed 180 people since January 2017.
The
outbreak of infectious
diseases like SARS and bird flu in Asia in recent years has increased the urgency of Canadian governments
at all levels to enhance their capacity to cope with possible future
outbreaks in this country.
«
At the end of the day we do need traceability to be prepared for exotic
disease outbreaks such as FMD but any system has to be cost - effective and practical,» Mr Feldtmann said.
Speaking
at the time, Sir Leslie Turnberg, Chairman of the UK Public Health Laboratory Service (PHLS) commented: ³ The vital importance of infectious
disease surveillance is clear from the global increase in infectious
diseases and the looming threat of antibiotic resistance... The effectiveness of the PHLS is beyond question, and the astonishingly swift identification of the cause of the recent
outbreak of salmonellosis from powdered baby milk undoubtedly saved many babies from becoming ill.
From the ill - advised fight with Uber, to accusations of mishandling the critical outreach portion of an
outbreak of Legionnaires»
disease in the Bronx, to his high profile spat with Gov. Andrew Cuomo, to his misadventures
at the Park Slope YMCA while a deadly standoff unfolded on Staten Island.
New York City Mayor Bill de Blasio has signed legislation aimed
at preventing future
outbreaks of Legionnaires»
Disease.
Cuomo: «We're Taking Matters into Our Own Hands» Gary Tilzer, Blogger
at True News, @unitedNYblogs On Friday, Politico New York reported on the gulf between Governor Andrew Cuomo and Mayor Bill de Blasio over the recent Legionnaires
disease outbreak in -LSB-...]
He cited homelessness, the criminal justice system and mental health care as issues that The Bronx continues to struggle with, and although he criticized the city for its handling of the homelessness issue, his overall tone was milder than in his 2016 speech, when he hinted
at a run for mayor and said the city had «failed» the borough during its
outbreak of Legionnaires»
disease.
SOUTH BRONX — The death toll in the worst
outbreak of Legionnaires»
disease in New York City history has risen to 12, and the number of people infected has gone up to 113, Mayor Bill de Blasio announced
at a press conference Monday afternoon.
Cuomo,
at his press conference, declined to critique the city's response to the Legionnaires»
disease outbreak but harshly criticized building owners who had not taken the state up on its offer to provide their properties with free testing for legionella bacteria, saying that their refusal to act could leave them facing legal consequences.
The group also accused Bello of renting a crowd to welcome the President on his arrival
at the airport, while paying no attention to an
outbreak of
disease in the state.
At a press conference on Saturday, the mayor tried to reassure New Yorkers that the worst of the
outbreak was over, saying that the
disease had been contained.
The spat also played out over the city's recent Legionnaires»
disease outbreak, when the administrations held dueling press conferences, and was on full display when Cuomo hosted Vice President Joe Biden
at a rally in the city on the minimum wage, one of de Blasio's key issues, and the mayor was nowhere to be seen.
LEGIONNAIRES» FALLOUT: Monday morning
at City Hall, Mayor Bill de Blasio will hold a bill - signing ceremony, beginning
at 10 a.m. (full details below), and then, around noon, «the Mayor, Speaker Melissa Mark - Viverito and elected officials will host a press conference to introduce new legislation to reduce future risk of Legionnaires»
disease, and provide an update on the containment of the
outbreak,» according to the mayor's public schedule.
«This is the deadliest
outbreak of a foodborne
disease that we've identified in more than a decade,» Dr. Thomas Frieden, director of the CDC, said
at a news conference today.
A pandemic is an epidemic (an
outbreak of an infectious
disease) that spreads worldwide, or
at least across a large region.
Almost 5000 people were killed by the
disease in Liberia, with 300 to 400 cases a week
at the
outbreak's peak.
With that in mind, Sarah Valway and colleagues
at the Centers for
Disease Control and Prevention in Atlanta and
at several other institutions were called to examine a suspected TB
outbreak in rural Tennessee in May 1995.
A communications expert in disaster readiness
at the Centers for
Disease Control and Prevention in Atlanta, Daigle created last year's cheeky Zombie Apocalypse campaign, designed to teach the social media generation how to survive natural disasters and uncontained infectious
outbreaks.
W. Ian Lipkin, director of the Jerome L. and Dawn Greene Infectious
Disease Laboratory
at the Mailman School of Public Health
at Columbia University, led the scientific team that identified the first U.S.
outbreak of West Nile virus in 1999.
«We found that in each of the regions we could analyze, Zika virus circulated undetected for many months, up to a year or longer, before the first locally transmitted cases were reported,» says Bronwyn MacInnis, an infectious
disease geneticist
at the Broad Institute, in Cambridge, Mass. «This means the
outbreak in these regions was under way much earlier than previously thought.»
The rare autoimmune
disease can lead to paralysis, and recently it appears to be occurring more frequently than usual within
at least eight countries and territories reporting Zika
outbreaks.
In the study, a tipping point represented the point
at which vaccine coverage declines dramatically due to spreading fear, which could cause large
disease outbreaks due to a loss of population immunity.
Dr. Lauren Ancel Meyers, senior author and Professor
at The University of Texas
at Austin, added: «Zika
outbreaks require the importation of the
disease by infected travellers followed by local mosquito - borne transmission.
Computer scientists and statisticians
at Colorado State University are turning
disease outbreak planning exercises into a game.
Age - specific incidence of the
disease peaked
at ages 10 to 11 in each
outbreak.
Wencui Han of the Department of Management Science and Systems
at the University
at Buffalo, New York and colleagues, explain how in the last two decades criminal incidents such as shootings on campus, assaults and robberies, natural disasters including tornadoes, hurricanes and snow storms and
disease outbreaks have put students and staff
at risk.
Aside from inflicting devastating natural disasters on often vulnerable communities, climate change can also spur
outbreaks of infectious
diseases like Zika, malaria and dengue fever, according to a new study by researchers
at the University of Colorado Anschutz Medical Campus.
At the same time, the El Niño event brought warmer sea - surface temperatures, which have been shown to correlate with
outbreaks of mosquito - transmitted
diseases.
A new center has opened
at Purdue University to create software to help manage complex crises such as
disease outbreaks and financial calamities.
Is the United States
at risk for a large - scale
outbreak of Zika or other mosquito - borne
disease?
The costly 2001 foot - and - mouth
disease outbreak in the U.K. was a result of an accident
at a similar research facility, the Post reported.
Basically 75 percent of all the emerging
diseases come from animals, and the seminar which brought together a group of diverse researchers, tried to look
at what we can do to better contain or spot potential
outbreaks.
In research outlined in the Journal of Infectious Diseases, scientists
at the University of British Columbia and the B.C. Centre for
Disease Control used genetic sequencing to trace the 2010 measles
outbreak, linking it back to an influx of visitors during the Winter Olympics.
Professor Paul Kellam, Group Leader of Virus Genomics
at the Wellcome Trust Sanger Institute, said: «Real - time analysis of virus genomes such as Ebola is an important addition to our toolkit for investigating
disease outbreaks.
Potential
outbreaks of
diseases such as Ebola and Lassa fever may be more accurately predicted thanks to a new mathematical model developed by researchers
at the University of Cambridge.
Disease wiki The site excels at natural - language processing, says Larry Madoff, founder and editor of the Program for Monitoring Emerging Diseases (ProMED), a global electronic mailing list that receives and summarizes reports on disease outbreaks and that was one of HealthMap's first sources o
Disease wiki The site excels
at natural - language processing, says Larry Madoff, founder and editor of the Program for Monitoring Emerging Diseases (ProMED), a global electronic mailing list that receives and summarizes reports on
disease outbreaks and that was one of HealthMap's first sources o
disease outbreaks and that was one of HealthMap's first sources of data.
Given the symptoms of the
disease and the rate of death, «C. novyi makes perfect sense» as the cause for the Glasgow
outbreak, says Martin Hugh - Jones, a veterinary epidemiologist
at Louisiana State University in Baton Rouge.
«It's pretty hard to know when you have an
outbreak of an unknown
disease if you don't even have diagnostics to rule out the known
diseases,» said Mark Smolinski, director of global health threats
at the Skoll Global Threats Fund.
Robert Colebunders, an infectious
disease clinician
at the University of Antwerp in Belgium, who was involved in treating Ebola patients in the 1995
outbreak, says if there are survivors willing to donate blood, doctors should try the therapy.
Influenza vaccines have been developed to prevent the yearly
outbreaks of this respiratory illness and to protect people
at risk from developing severe
disease.
The study, published Wednesday in Psychological Science in the Public Interest, a journal of the Association of Psychological Science, comes
at a time when
outbreaks of influenza and other communicable
diseases are cropping up with seemingly increased frequency.
«It's like after a flu
outbreak,» says Ryan Harrigan, an infectious
disease biologist
at the University of California, Los Angeles, and one of the authors of the study.
Closer to home, recent
outbreaks of fungal
diseases in the forests of western North America have been linked to warmer and wetter conditions
at specific times of year.
Yesterday, director Li Liming of the Center for
Disease Control and Prevention (CDC) resigned, along with several lower - ranking officials, after a report by a panel of experts blamed China's most recent
outbreak of severe acute respiratory syndrome on a series of flaws
at the CDC's National Institute of Virology in southern Beijing.
The Reunion
outbreak is «an opportunity to reactivate the research effort and to bring the vaccine to licensure,» says Colonel David Vaughn, who heads the infectious
disease research program
at the U.S. Army Medical Research and Materiel Command.
And it remains far from clear that bats are the hosts of the deadly zoonotic
disease since two similar surveys of thousands of animals, including bats,
at sites where human
outbreaks occurred in the past failed to turn up any sign of Ebola virus.