Sentences with phrase «disease phenotype data»

The IMI could also control and organize access to metadata (the associated host disease phenotype data, for a human gut microbiota sample, for instance) without which meaningful interpretation of the data is not possible.

Not exact matches

The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.

Personalised Medicine initiatives will benefit greatly from this emerging data and biological resources which can be used to detect novel genotype - to - phenotype associations in diseases.

The Human Phenotype Ontology project: linking molecular biology and disease through phenotPhenotype Ontology project: linking molecular biology and disease through phenotypephenotype data.

INFRAFRONTIER will provide open access to all newly developed disease models and phenotyping data.

Having investigated the different representations of phenotypes, she applies this knowledge to data integration and human genetic disorders with the aim of improving the understanding about the molecular mechanisms underlying human diseases.

It has been set up to address the problem of fragmentation in the rare disease research field, where individual efforts often have poor interoperability and do not systematically connect data across the levels of clinical phenotype, genetics and omics data, biomaterial availability and research / trial datasets.

The scale and scope of these data are enabling genotype - phenotype association studies to identify genetic determinants of pathogen virulence and drug / insecticide resistance, and phylogenetic studies to track the origin and spread of disease outbreaks.

This data is essential to ensure that the phenotype (visible symptoms of a disease) is correctly categorized.