Sentences with phrase «disease proteins»
Research in Parkinson's and Huntington's has uncovered additional examples of disease proteins that, when mutated, stymie protein clearance pathways in neurons.
scientificamerican.com
In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells.
«Parkinson's disease protein plays vital «marshalling» role in healthy brains.»
Once inside the cell, enzymes cleave off the neutral phosphotriester group to expose a charged RNAi drug that shuts down production of the target disease protein.
We are also interested in the effect of 7B2 and proSAAS on Parkinson's disease protein aggregates, known as Lewy bodies, which are formed from synuclein protein within brain stem areas that control movement, and have recently shown that proSAAS overexpression blocks cell death in neuronal cell cultures.
Max Planck researchers have found that a stress - related protein can increase the chances of diabetes — and blocking the protein could prevent the disease
THURSDAY, Dec. 8, 2016 (HealthDay News)-- Higher blood levels of a specific heart disease protein are associated with brain damage, a new study suggests.
See GENETICS: Inherited Urinary Tract Disorders for the following: Familial Kidney Disease Fanconi Syndrome Polycystic Kidney Disease Protein - Losing Nephropathy Renal Dysplasia Urethral Shaft Abnormality
Scientists from the Crick Institute, London and the Hebrew University, Jerusalem, discover a protein that plays a key role in turning cancer tumor cells into cancer stem cells that are able to renew outbreaks of the disease
Last year Cuervo collaborated with Sheng Zhang, a professor at The University of Texas Health Science Center at Houston on experiments showing that huntingtin — the Huntington's disease protein — helps the cell's autophagy system identify what it should eliminate.
In the search for better treatments for this disease the protein Sclerostin, which plays an important role in bone metabolism, is of major interest.
«New method to reduce accumulation of damaging Huntington's disease protein.»
«Alzheimer's disease proteins could be at fault for leading cause of vision loss among older people.»
First, researchers generate RNAi drugs with a sequence that corresponds to the gene blueprint for the disease protein and then delivers them into cells.
The press release from Lund University accompanying this article was titled «Breakthrough On Huntington's Disease», and contained a quote from Dr Petersen stating «We are the first to show that it is possible to prevent the depression symptoms of Huntington's disease by deactivating the diseased protein in nerve cell populations in the hypothalamus in the brain».
«We knew nothing about the identity of neurofibrillary tangles or senile plaques or any of these disease proteins in neurodegenerative diseases,» says Lee.
So she and Trojanowski decided to make it their goal to isolate systematically and identify the disease proteins in neurodegenerative disorders, starting with Alzheimer's disease.
A new exciting chapter in Huntington's disease (HD) treatment is just beginning — WAVE Life Sciences have announced PRECISION - HD1 and 2, clinical trials of two new drugs that lower the mutant Huntington's disease protein.
Clumps that form from these disease proteins are composed of sticky fibrils that damage nerve cells.
He has used these techniques to study a crucial Parkinson's disease protein, alpha - synuclein.