Sentences with phrase «disease than normal mice»

REG3G - deficient mice also developed more severe alcoholic liver disease than normal mice.

Not exact matches

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

Furthermore, more than 75 % of mice infected with virus bearing the normal protein developed severe corneal autoimmune disease, whereas fewer than 20 % of mice infected with mutant virus did, and their symptoms were barely detectable.

Experiments on mice and on heart cells obtained from infants born with congenital heart disease suggest that neuregulin 1, a human growth factor, can put infant heart cells on a path that mimics normal growth rather than stalling out.

Sinclair's lab is now working on developing what he calls a possible «supermouse» with elevated levels of NAMPT to see if it lives longer and is more disease - resistant than normal mice.

The mice that were fed a calorie - restricted diet, mainly by a reduction in their carbohydrate intake, over a period of six months, had fewer disease symptoms than their normal - diet counterparts.

They found that the mice developed earlier and more severe disease than mice that had normal Tob1 expression in all cells including CD4 +.

It should be noted, however, that while a study on senescent cell ablation in genetically normal mice would provide at least some evidence on the effect of senescent cells (and their ablation) on promoting cancer, even such a study would likely show less effect than could be anticipated in a large mammal model, since even normally - aging mice rarely suffer metastatic disease to the extent of aging humans, as sheer primary tumor volume is generally sufficient to be fatal to mice.

Results showed the first two groups didn't develop PCOS, unlike the mice in the control group, whereas the test subjects with ovary ARs still contracted the disease, albeit at a lower rate than the normal mice.