Sentences with phrase «disease therapy as»
The National Institutes of Health awards UC San Diego School of Medicine researchers an inaugural grant to fast - track development of a novel Alzheimer's disease therapy as part of its $ 50 million Blueprint for Neuroscience Research.
https://health.ucsd.edu/ Not exact matches
Spending on new drugs for those diseases is expected to rise 7 % in 2018, and it's less due to price hikes as it is for the high prices associated with these specialty therapies.
Luxturna is the first of a crop of treatments that target diseases caused by mutations in specific genes, and thus is referred to by many as the first gene therapy in the U.S.
That could be key for therapies that tend to be hard to deliver, such as drugs to treat gastrointestinal diseases where Suono is starting out.
LONDON, April 12 - GlaxoSmithKline is divesting its rare disease gene therapy drugs to private biotech company Orchard Therapeutics as Chief Executive Emma Walmsley makes good on her promise to prune the drugmaker's pharmaceuticals portfolio.
LONDON, April 12 - GlaxoSmithKline is divesting its rare disease gene therapy drugs to Orchard Therapeutics, it said on Thursday, as Chief Executive Emma Walmsley makes good on her promise to prune the drugmaker's pharmaceuticals portfolio.
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.
But company leadership also maintained that the drug is a «best - in - class anti-inflammatory disease - modifying therapy,» as Chief Executive Officer Stuart Peltz said on the company's earnings call.
After Heron Therapeutics Inc (NASDAQ: HRTX), Bristol - Myers Squibb Co (NYSE: BMY) and Dynavax Technologies Corporation (NASDAQ: DVAX) found favor with the FDA, it's Ultragenyx Pharmaceutical Inc (NASDAQ: RARE)'s turn, as the rare disease therapy company seeks FDA approval for its...
But the field of medicine is changing rapidly, and fortunes will be made as new technologies produce therapies to treat diseases that were previously intractable.
«They also are more likely to require more mental health therapy; identify themselves as homosexual; choose cohabitation; be unfaithful to partners; contract sexually transmitted diseases; be sexually molested; have lower income levels; drink to get drunk; and smoke tobacco and marijuana.»
And as CSL devises new therapies and shows that existing therapies can treat new diseases, and health authorities spend more, its revenues and profits outpace the growth in demand for conventional therapies.
Dietary medium - chain triglycerides prevent chemically induced experimental colitis in rats: Medium chain triglycerides show promise for nutritional therapy of inflammatory bowel disease (e.g., Crohn's disease and colitis) as an anti-inflammatory nutrient in the colon.
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
Diarrhoea is, in reality, as much a nutritional disease as one of fluid and electrolyte imbalance, and therapy is not adequate unless both aspects of the disease are treated.
Synthetic marijuana was first developed in the South Carolina lab of a Clemson University professor as part of research into therapies for osteoporosis, liver disease and some kinds of cancer.
«As a consequence, and assuming that others can replicate our findings, that could lead to therapies, ways of prevention, and ways of anticipating disease that don't now exist.»
Some comes from another of his collaborations, with Glenna Batson, a WSSU physical therapy colleague who is studying dance as a rehabilitation therapy for patients with Parkinson's disease.
«While electrical stimulation of the brain is emerging as potential therapy for a wide range of neurological and psychiatric diseases, little is known about its effect on memory,» says Gregory Worrell, M.D., Ph.D., a Mayo Clinic neurologist and senior author of the article.
The finding is far from definitive evidence of safety, but it's some of the first published animal research supporting the use of this type of RNA as long - term therapy in diseases like methylmalonic acidemia (MMA).
Gene therapies promise to revolutionize the treatment of many diseases, including neurological diseases such as ALS.
But after four decades as a standard therapy for heart disease and high blood pressure, it looks like this fate will befall beta blockers.
They isolated blood cells from HIV - positive patients on antiretroviral therapy and at different stages of disease progression, as well as cells from non-infected individuals.
The trial included 501 patients with atherosclerotic cardiovascular disease (ASCVD) and elevated LDL cholesterol (> 70mg / ml) despite maximum tolerated statin therapy and patients without ASCVD but with high cardiovascular risk conditions such as diabetes and familial hypercholesterolaemia in whom LDL cholesterol was > 100mg / dl despite maximally tolerated statin therapy.
Experts say these findings provide a new window into the way the brain operates and why certain enigmatic disorders such as autism and Alzheimer's disease may develop, potentially paving the way for new therapies to treat them.
These human genes were also protective against alpha - synuclein - induced death, suggesting that they could be worth testing as gene therapy treatments for Parkinson's disease, Lu says.
It could also lead to the development of new therapies against other more common neurodegenerative disorders of the central nervous system, as well as diseases related to the propagation of pathological proteins, including Parkinson's and Alzheimer's.
Prof. Severine Vermeire (KU Leuven / UZ Leuven): «In the future, gut bacteria may be used to help identify PSC patients with a more or less aggressive disease, or patients that may benefit from microbiota - based therapies, such as fecal microbiota transplantation or targeted pre - and probiotics.»
This is advantageous, since dogs provide new models to investigate the disease mechanisms and to plan new therapies such as gene therapy, successfully applied to blindness in dogs and human previously,» explains Lohi.
A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.
According to the authors, placebo effects can dramatically enhance the effectiveness of pharmaceutical therapies, as shown in studies of patients with irritable bowel disease and episodic migraine.
What's more, the researchers who made the discovery say their finding will aid in the design of therapies for thyroid problems, such as Graves» disease, and problems with other glands that operate in a similar fashion.
«Understanding the molecular mechanisms by which asthma develops and establishes itself as a chronic disease is key to elucidating alternative and potentially curative therapies,» said Dr. Grayson.
«These brain makers are the same across dozens of neurological diseases, as well as brain trauma, so you can test potential therapies not just for schizophrenia, but for conditions such as Parkinson's, Alzheimer's, bi-polar disorder, and traumatic brain injuries,» says Gil - da - Costa.
«Our results indicate it is a promising agent for clinical trials, and a as an add - on to more conventional therapies, to prevent tumour recurrence, further disease progression and metastasis.»
If the results are right, and if certain gut bacteria are necessary for MS, they could serve as the basis for microbiome - based therapy or even prevention of the disease.
The new research investigated the effectiveness of MSC therapy in a mouse model of chronic inflammatory lung disease, which reflects some of the essential features of diseases such as COPD and cystic fibrosis.
Tissue engineering provides a more practical means for researchers to study cell behavior, such as cancer cell resistance to therapy, and test new drugs or combinations of drugs to treat many diseases.
Researchers at the University of Louisville have discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell therapies for diseases such as muscular dystrophy.
And in an ironic twist, the work could yield a new way to treat common ailments such as heart disease and cancer with gene therapies.
By the mid-1990s, the terror of the early AIDS epidemic had subsided in many western countries, as antiretroviral therapy transformed the once - deadly disease into a chronic condition.
«Despite the progress and the success of viral eradication, numerous questions remain unanswered such as response based on race, still difficult - to - treat situations such as patients with end - stage liver disease or undergoing hemodialysis, access to and affordability of these therapies, improvement in quality of life, and cost - effectiveness.
While some bioidenticals have been approved by the FDA and prescribed for years, most have not, and doctors argue that these «natural» hormones could trigger disease as easily as conventional hormone therapy.
They give some clues about why these diseases occur, but more detailed maps, such as this, will pinpoint where the problems lie — providing precise targets for therapies.
New products and developments, such as new drugs for cancer, fresh therapies for rare diseases, progress in medications for HIV / AIDS, and advances in stem cell research had the greatest positive impact.
Our development pipeline is focused on areas of high unmet medical need, as we pursue new therapies for diseases with few or no treatment options.
Genzyme, for example, is committed to developing innovative therapies for diseases such as malaria and sleeping sickness that have largely disappeared in the industrial nations but affect millions in Third World countries.
Eye diseases — such as age - related macular degeneration, as well as a genetic condition called Stargardt's macular dystrophy that afflicts young people — are considered excellent candidates for stem cell therapy because the eye is an immune - privileged site, meaning transplanted cells are not as likely to be rejected as foreign compared with transplants elsewhere.
The fact that TAS - 102 temporarily halted the disease in many of these patients suggests that it operates through a different biochemical pathway than 5 - FU, and therefore may serve as an alternative to standard therapy.
«It is expected that this study will lay the foundation for developing a new class of potent and effective cancer therapies and the development of reagents targeting epigenetic events in immune - mediated diseases as well as other epigenetically - influenced diseases,» said Alani, who also is chief of dermatology at Boston Medical Center.