Not exact matches
Her lab is now developing a model system for Parkinson's
disease that includes brain, liver, and gastrointestinal
tissue, which she plans to use to investigate the hypothesis that bacteria found in the
gut can influence the development of Parkinson's
disease.
To better understand this complex
tissues and its functions — and the
diseases that affect it — a multicenter team led by researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital has released a census of the cells that make up the lining of the small intestine, using gene expression profiles of more than 53,000 individual cells from the mouse
gut or
gut organoid models.
Adult stem / progenitor cells are present in many organs and
tissues, e.g., bone marrow, teeth, heart,
gut, kidney and liver, and remain quiescent for long period of time until activated by a
disease or injury trigger.
ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal
tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the
gut that can be caused by disorders such as inflammatory bowel
disease (IBD).
gastroenterology A branch of medicine that deals with the
tissues and
diseases of the
gut — those food - processing organs that include the stomach and intestines.
These 45 variants are significantly enriched for protein - coding changes (n = 13), direct disruption of transcription - factor binding sites (n = 3), and
tissue - specific epigenetic marks (n = 10), with the last category showing enrichment in specific immune cells among associations stronger in Crohn's
disease and in
gut mucosa among associations stronger in ulcerative colitis.
To be diagnosed with most autoimmune
diseases, the immune system has to destroy a significant amount of
tissue (such as the brain,
gut, or thyroid) to be officially diagnosed.
The top 10 that are most common in the United States are: Hashimoto's
Disease (Hypothyroidism) Graves»
Disease (Hyperthyroidism) Rheumatoid Arthritis (Joints) Lupus (Multiple
tissues) Sjogren's Syndrome (Dry Eyes, Skin, and Mouth) Celiac
Disease (
Gut) Psoriasis (Skin and Joints) Multiple...
Authors conclude «restoration of normal menses was caused by reduced inflammation in the ovarian
tissue and supports the hypothesis that the
gut immune system can influence autoimmune
disease and inflammation.»
Unfortunately, high levels of nitric oxide in the
gut have been shown to worsen the
tissue damage and inflammation experienced in Crohn's
disease and ulcerative colitis.
Short chain fatty acids may modulate
tissue levels and effects of growth factors in the
gut and so modify
gut development and risk of serious
disease, including colo - rectal cancer.
Hashimoto's is a complex
disease, whose causes are too complex to explore in this post, but in my opinion it is generally caused by exogenous toxins (gluten, mercury, bisphenol - A, bromide, etc) that disrupt
gut flora and cause
gut permeability and disturbed immunity that allows infections to enter the body and take root in thyroid
tissue, after which in susceptible persons an autoimmune attack on the thyroid can develop.