Sentences with phrase «diseased host animals»

«We were astonished to realize that the tumors did not arise from the cells of their diseased host animals, but rather from a rogue clonal cell line spreading over huge geographical distances,» Goff said.

Not exact matches

Where is the clear line in a progression from (1) using animal insulin to treat diabetes, to (2) using gene remodeling techniques to grow insulin in a host bacterium that will reproduce rapidly and from which a plentiful supply of insulin can be harvested, to (3) genetic surgery to replace the defective gene in a person diagnosed as diabetic, to (4) genetic surgery immediately after fertilization in order to replace the defective gene and alter the germ cells which would otherwise have transmitted the disease to one's offspring?

If dozens of human and animal studies published over the past six years are borne out by large clinical trials, nicotine — freed at last of its noxious host, tobacco, and delivered instead by chewing gum or transdermal patch — may prove to be a weirdly, improbably effective drug for relieving or preventing a variety of neurological disorders, including Parkinson's disease, mild cognitive impairment (MCI), Tourette's and schizophrenia.

Morse is credited with creating the term emerging infectious diseases in the late 1980s to explain viruses that can exist for years in an animal host without causing illness.

In the tropics, disease sources have included a host of wild animals, most notably the nonhuman primates.

Since the sexual reproduction stage of malaria only occurs in insects, Poinar said in the new study that they must be considered the primary hosts of the disease, not the vertebrate animals that they infect with disease - causing protozoa.

Wild boar and red deer are key hosts of bovine tuberculosis — a chronic, infectious disease mainly caused by Mycobacterium bovis — in southern Europe, with the incidence of TB in these animals particularly high in certain areas of Spain.

It has been suspected in humans, and shown in animal models, that the host's immune responses can make disease worse.

The new report describes experiments in mice showing how genetic variation in a host animal shapes the microbiome — a rich ecosystem of mostly beneficial microorgannisms that resides in the gut — and sets the table for the onset of metabolic disease.

Coyotes are overtaking the red fox, which feeds on small mammals such as mice, shrews and chipmunks, animals that, like deer, can play host to the Lyme - disease - carrying ticks

The red fox feeds on small mammals such as mice, shrews and chipmunks, animals that, like deer, can play host to the Lyme - disease - carrying ticks.

And it remains far from clear that bats are the hosts of the deadly zoonotic disease since two similar surveys of thousands of animals, including bats, at sites where human outbreaks occurred in the past failed to turn up any sign of Ebola virus.

The white - footed mouse (top) isn't the main animal host for Lyme disease; the short - tailed shrew (bottom) and others are just as important.

It makes a toxin that deters insects and other animals from eating the plant and also protects its host against disease and drought.

Studies of related viruses indicate that some have evolved disease - free coexistence with their animal hosts

A growing number of studies have demonstrated that, at least in animals, these unusual fats fight a host of chronic health conditions from heart disease to diabetes to cancer (SN: 3/3/01, p. 136).

Although T. brucei gambiense has also been found in various wild and domestic animal species, these are usually considered sporadic, «dead - end» hosts, from which the disease isn't transmitted further.

The new report describes experiments in mice showing how genetic variation in a host animal shapes the microbiome — a rich ecosystem of mostly beneficial microorganisms that resides in the gut — and sets the table for the onset of metabolic disease.

In the paper, the authors stressed that understanding the genetic makeup of these molluscs is important because many «freshwater snails are intermediate hosts for flatworm parasites and transmit infectious diseases» to humans and other animals.

IDMIT is an infrastructure for preclinical research in infectious diseases and immunology which is certified ISO9001 and which includes 1) A large animal facility with capacity to host NHP in BSL2 and BSL3 containment, 2) State - of - the - art laboratories for cell biology, immunology, molecular biology, flow cytometry and mass cytometry (CyTof), cell - sorting and confocal microscopy in BSL3 containment; 3) A biological resources centre with high storage capacity; 4) Highly innovative technologies for in vivo imaging of large animals in BSL2 and BSL3 containment, including a two - photon microscope, a PET - CT facility, and several optic based technologies (fibered endo - microscopy, near infra - red imaging).

The focus is on molecular microbiology and virology, and includes topics such as genomics, the gamut of plant and animal host - pathogen interactions, host immune responses, characterization and evolution of virulence determinants, cell cycle and differentiation, symbiosis in plant and animal associations, environmental microbiology, biodiversity and evolution, population dynamics, sex and mutagenesis, antibiotic resistance and production, drug and vaccine targets, as well as aspects of prion diseases and of fungal and protozoan biology.

- host disease in an animal model.

Some species of ticks carry these bacteria and transmit the disease while feeding on a new host animal's blood.

To acquire the disease, the host cat must consume raw meat or live animals that are infected with toxoplasmosis.

Hit by cars, mauled by dogs and other larger animals, poisoned, and notably dying of a host of parasitic diseases, feral and stray cats have an average life span of less than 3 years.

Ticks feed on an animal's blood and can transmit a variety of diseases in their host.

Control of canine distemper outbreaks includes the removal of carcasses of animals which have died from the disease, vaccination of susceptible domestic species to decrease the number of susceptible hosts, and a reduction in wildlife populations which also reduces the number of potential hosts.

Besides drinking an animal's blood and causing truly demonic itching (especially if your pet suffers from flea allergy dermatitis), fleas can bring on anemia and a host of diseases.

Because of the specter of antimicrobial resistance looming as a threat to the health of horses, people, and other animals, we are particularly interested in how we can develop approaches to treatment and prevention of infectious diseases that are based on improving effectiveness of host immune responses to control infection (rather than using antimicrobial drugs).

The FWCC itself acknowledges the following: cats are the most common carriers of rabies among domestic animals, and can transmit rabies to wildlife such as raccoons, skunks an foxes; feline leukemia virus, a leading cause of death due to infectious disease in cats, has been reported in a mountain lion, a close relative of the endangered Florida panther; domestic cats were identified as one possible reservoir host for feline panleukopenia, which has been discovered in the Florida panther.

Outdoor cats fall prey to cars, animal attacks (including dogs, wildlife and other cats), human abuse, poisoning, traps and a host of diseases, including rabies.

Infectious disease transmission is sensitive to local, small - scale differences in weather, human modification of the landscape, the diversity of animal hosts, 71 and human behavior that affects vector - human contact, among other factors.

The development and survival of blacklegged ticks, their animal hosts, and the Lyme disease bacterium, Borrelia burgdorferi, are strongly influenced by climatic factors, especially temperature, precipitation, and humidity.

The Forum on Microbial Threats hosted a public workshop in Washington, DC to consider the possible infectious disease impacts of global climate change and extreme weather events on human, animal, and plant health, as well as their expected implications for global and national security.