Sentences with phrase «diseases of the aging brain»
Yet one - third of global health issues are related to neurological problems, such as depression, pain, and the diseases of the aging brain.
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Work at the institute focuses on disorders of the developing brain, such as autism and attention deficit disorder; diseases of the aging brain, including Alzheimer's and Parkinson's; and restoring function to the damaged brain, including brain - machine interfaces and deep brain stimulation.
Not exact matches
Though the researcher said there needs to be more research into the exact mechanisms of why that is, they concluded that «healthy sleep appears to play an important role in maintaining brain health with age, and may play a key role in [Alzheimer's disease] prevention.»
Blueberries softens dry skin, boosts your brain, fight urinary tract infections, may even prevent cancer and lower risk of age related diseases like Alzheimer's disease.
A study from the University of California - Los Angeles Easton Center for Alzheimer's Disease Research shows people with diets deficient in omega - 3 fatty acids were more susceptible to accelerated brain aging.
These current studies represent a leap forward in the knowledge base about HS - AGING, and represent potential new paths to explore for diagnosis and treatment of this serious, but under - appreciated brain disease.
Dr. Saper's research has explored circuitry of the brain that controls basic functions such as wake - sleep cycles, feeding, and immune response, and how these circuits are disrupted in neurological disorders, such as Parkinson's disease, in sleep disorders such as narcolepsy and sleep apnea, and during aging.
«Cognitive aging is not a disease or a level of impairment — it is a lifelong process that affects everyone,» explains lead author Dr. Sharon K. Inouye, Director of the Aging Brain Center at the Institute for Aging Research, Hebrew SeniorLife in Boston, Massachusetts and Professor of Medicine, Harvard Medical Scaging is not a disease or a level of impairment — it is a lifelong process that affects everyone,» explains lead author Dr. Sharon K. Inouye, Director of the Aging Brain Center at the Institute for Aging Research, Hebrew SeniorLife in Boston, Massachusetts and Professor of Medicine, Harvard Medical ScAging Brain Center at the Institute for Aging Research, Hebrew SeniorLife in Boston, Massachusetts and Professor of Medicine, Harvard Medical ScAging Research, Hebrew SeniorLife in Boston, Massachusetts and Professor of Medicine, Harvard Medical School.
Three recent papers authored by Dr. Peter Nelson and others at the University of Kentucky Sanders - Brown Center on Aging, explore the neuropathology behind a little - understood brain disease, hippocampal sclerosis (known to scientists and clinicians as HS - AGAging, explore the neuropathology behind a little - understood brain disease, hippocampal sclerosis (known to scientists and clinicians as HS - AGINGAGING).
26 — 30 People who live to age 100 in good health often have brain lesions that are characteristic of Alzheimer's disease.
A mouse engineered to have Alzheimer's disease and a gradual reduction in levels of the brain enzyme BACE1 stopped forming plaques (arrows in the first panel) as it aged.
The scientists compared that tissue with brain tissue samples from three young amateur American football players and a professional wrestler, all of whom had a history of repetitive concussive injury, and with four samples from comparably aged control subjects with no history of blast exposure, concussive injury or neurological disease.
«By learning how tau spreads, we may be able to stop it from jumping from neuron to neuron,» said Karen Duff, PhD, professor in the department of pathology and cell biology (in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) and professor of psychiatry (at New York State Psychiatric Institute.)
Facing the specter of Alzheimer's disease, the most devastating and widespread manifestation of brain deterioration in old age, worried baby boomers have inspired whole catalogs of brain - fitness books and services.
Researchers derived data from the Harvard Aging Brain Study, an observational study of older adult volunteers aimed at defining neurobiological and clinical changes in early Alzheimer's disease.
After controlling for factors known to influence brain volume and cognitive test scores, such as age and gender, the researchers found that a higher self - reported frequency of game playing was significantly associated with greater brain volume in several regions involved in Alzheimer's disease (such as the hippocampus) and with higher cognitive test scores on memory and executive function.
Research from Washington University School of Medicine in St. Louis, Radboud University Medical Centre in the Netherlands, and Stanford University shows that disrupting just one night of sleep in healthy, middle - aged adults causes an increase in a brain protein associated with Alzheimer's disease.
Physicists have devised a new method of investigating brain function, opening a new frontier in the diagnoses of neurodegenerative and aging related diseases.
An increased amount of miRNA in brain cells was correlated with a younger age at disease onset and an earlier age at death of the patients.
«This study, carried out using laboratory rats modeling stroke, demonstrated that ischemic stroke — in both its subacute and chronic stages — damages the BSCB in a variety of ways, creating a toxic environment in the spinal cord that can lead to further disability and exacerbate disease pathology,» said study lead author Dr. Svitlana Garbuzova - Davis, associate professor in USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair.
«Alzheimer's brains usually contain evidence of neuroinflammation, and researchers increasingly think that this could be a possible driver of the disease, by causing neurons in the brain to degenerate,» says David Emery, a researcher from the University of Bristol, and an author on the study, which was recently published in Frontiers in Aging Neuroscience.
Amyloid — an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's disease — starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined, reports a surprising new Northwestern Medicine study.
Amyloid — an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's disease — starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined.
«Everybody else hopes that you can make use of that [nerve cell production] to treat neurodegenerative diseases,» such as Parkinson's disease, or even to encourage the aging brain to regenerate by stimulating the production of new nerve cells, he says.
For the study, scientists examined the brains of 36 male athletes, ages 17 to 98, diagnosed with CTE after death, and who had no other brain disease, such as Alzheimer's.
The researchers found that TyrNovo's novel and unique compound, named NT219, selectively inhibits the process of aging in order to protect the brain from neurodegenerative diseases, without affecting lifespan.
I am exploring what diseases might be lurking in my head; what my memory is like at the age of 51; and how my brain responds to matters as diverse as fear, greed, the movies I like, and even the idea of God.
Published in the Neurobiology of Aging, the study, which focused on detecting changes in the white matter connections of the brain, offers tantalizing potential for the identification of biomarkers connected to the development of dementia, including Alzheimer's disease.
In addition, we're very far away in research from really understanding the aging brain, fixing Alzheimer's disease, stopping all kinds of dementia - related diseases.
After researchers adjusted for age, sex, race, education and other health conditions like diabetes and high blood pressure, they found that those with any kind of traumatic brain injury had a 71 percent increased risk of Parkinson's disease, those with moderate to severe traumatic brain injury had an 83 percent increased risk, and those with mild traumatic brain injury had a 56 percent increased risk of Parkinson's disease.
In the case of Parkinson's disease, it is found that the expression of MAO - B, but not MAO - A, is significantly enhanced in the brain of patients and increases with age.
Acceleration of aging may actually be part of the mechanism by which degenerative disease disrupts the structure and function of the brain,» said Dr. Giniger.
Researchers from Kent State University's College of Arts and Sciences, along with colleagues from the George Washington University, Yerkes National Primate Research Center, Georgia State University, Barrow Neurological Institute and the Icahn School of Medicine at Mount Sinai, found that the brains of aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer's disease brain.
However, a new study published Aug. 1 in Neurobiology of Aging provides the most extensive evidence of Alzheimer's disease brain pathology in a primate species to date.
«The presence of amyloid and tau pathology in aged chimpanzees indicates these Alzheimer's disease lesions are not specific to the human brain as generally believed,» Hof continued.
«New possibility of studying how Alzheimer's disease affects the brain at different ages.»
Kent State University researchers analyzed the brains of aged chimpanzees to show pathology similar to the human Alzheimer's disease brain.
That variety cropped up in a different part of the brain than the other strains, and it also produced clumps of proteins akin to the amyloid plaques found in sporadic Creutzfeldt - Jakob disease, a fatal brain disease of unknown origin that usually affects those over age 55.
Although much research has examined traumatic brain injury (TBI) as a possible risk factor for later life dementia from neurodegenerative diseases such as Alzheimer's disease (AD), little is known regarding how TBI influences the rate of age - related cognitive change.
The authors also found abnormalities in the subthalamic nucleus occur earlier than in other brain regions, and that subthalamic nucleus nerve cells progressively degenerate as the mice age, mirroring the human pathology of Huntington's disease.
Understanding the dynamic mechanisms that lead to the emergence of brain functions through the development and continuous remodelling of neural circuits, and the constraints that disease and aging impose to this multi-modal plasticity has important implications that go beyond fundamental neuroscience, from education policies to brain repair.
Recent research suggests one benefit of environmental enrichment at the cellular level: it repairs brain myelin, the protective insulation surrounding axons, or nerve fibers, which can be lost because of aging, injury or diseases such as multiple sclerosis.
Abnormal levels of the proteins may be useful biomarkers that could help us study early treatments to limit or reverse the damage to brain cells and even prevent the development of the full - blown disease,» said study author Edward Goetzl, MD, a Professor of Medicine with the University of California, San Francisco, a researcher at the National Institute on Aging, and a scientist of NanoSomiX, Inc., a California - based biotechnology company that provided a grant for method development for the study.
A digital map of the aging brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests.
Although what drives this process has not been clear, studies have indicated that caspace - 2 might be involved, according to senior author Michael Shelanski, MD, PhD, the Delafield Professor of Pathology & Cell Biology, chair of the Department of Pathology & Cell Biology, and co-director of the Taub Institute for Research on Alzheimer's Disease and the Aging Brain at CUMC.
Neuroscientist Mu - Ming Poo discusses the China Brain Project and its goal of understanding brain diseases in the most populous country's aging puBrain Project and its goal of understanding brain diseases in the most populous country's aging pubrain diseases in the most populous country's aging public.
«These results suggest that inflammation in mid-life may be an early contributor to the brain changes that are associated with Alzheimer's disease and other forms of dementia,» said study author Keenan Walker, PhD, of Johns Hopkins University School of Medicine in Baltimore, Md. «Because the processes that lead to brain cell loss begin decades before people start showing any symptoms, it is vital that we figure out how these processes that happen in middle age affect people many years later.»
Collectively, these avenues are aimed at moving towards defining the role of activated microglia in ageing and neurodegenerative disease, while considering the impact of systemic infections on the brain in multiple vulnerable neurodegenerative and neurodevelopmental states.
«We discovered that these fatty acids are produced by the brain, that they build up slowly with normal aging, but that the process is accelerated significantly in the presence of genes that predispose to Alzheimer's disease,» explained Karl Fernandes.
These processes often break down as a result of aging, neurodegenerative disorders (e.g. Alzheimer's disease), or traumatic brain injury, and the new findings provide a roadmap to examine strategies to improve these functions.