Sentences with phrase «disordered brain circuitry»

Karl Deisseroth, an optogenetics pioneer at Stanford University, has used the technique with animals to learn more about the nature of the disordered brain circuitry in Parkinson's.

Not exact matches

Dr. Saper's research has explored circuitry of the brain that controls basic functions such as wake - sleep cycles, feeding, and immune response, and how these circuits are disrupted in neurological disorders, such as Parkinson's disease, in sleep disorders such as narcolepsy and sleep apnea, and during aging.

The researchers also found disorder - specific involvement of the brain's «fear circuitry» in patients with SAD and involvement of the visual recognition network in patients with MDD.

But new studies suggest it may be a distinct disorder with its own unique signature in the circuitry of the brain.

New insights into the brain's fear circuitry could yield more effective treatments for anxiety disorders

«The project's goal is to accelerate the development of technologies for mapping the brain's circuitry in animal models, specifically in the marmoset monkey, whose neural circuits are much closer to human compared with rodent models, and to connect the results to the diagnosis and treatment of human neurological disorders and mental illness.»

«Disturbances to these processes may cause neuronal stem cells to develop into different types of cells or may cause neurons to migrate to different locations in the brain, changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»

My main goals are: a) to unravel the functional and anatomical connectivity of the primate prefrontal cortex circuitry within the framework of complex cognitive tasks, b) to generate tools and techniques that allow manipulating prefrontal cortex function and therefore generate symptoms of mental disorders in behaving non-human primates, and c) to produce interventions (e.g., deep brain stimulation or local / systemic drug delivery) that allow rescuing the generated disease phenotypes.

We hope that our work will provide new insight into the signaling mechanisms responsible for establishing brain circuitry, and ultimately suggest therapeutic interventions for disorders in which these signaling mechanisms are perturbed.

Scientists around the world have used optogenetics to reveal the brain circuitry underlying normal neural function as well as neurological disorders such as autism, obsessive - compulsive disorder, and depression.

Conversely, experiences that produce maladaptive changes in brain circuitry underlie many neuropsychiatric disorders, and age - related decreases in brain plasticity contribute to age - related memory disorders such as Alzheimer's disease.

SAN FRANCISCO, CA — April 29, 2012 — Scientists at the Gladstone Institutes have determined how specific circuitry in the brain controls not only body movement but also motivation and learning, providing new insight into neurodegenerative disorders such as Parkinson's disease — and psychiatric disorders such as addiction and depression.

14C -2-deoxyglucose autoradiography screen for mouse brain activity: relating known therapeutics and novel compounds for schizophrenia, depression, and bipolar disorder to brain circuitry A. GIOVANNI, S. ENGEL, C. BOWEN, R. TERRY - LORENZO, P. G. JONES, L. HARDY, T. LARGE, T. HANANIA, E. V. SABATH, V. ALEXANDROV, M. QUTAISH, M. SEAMAN, P. CZARNECKI, M. SILVA, J. SULLIVAN... Abstract > / Posters