Sentences with phrase «disorders such»

«Jumping genes» (in green neuron) may help ensure that every brain is unique, but could also contribute to neurological disorders such as schizophrenia.
Compared with controls, there was a 1.1-fold increase in L1 in the tissue of people with schizophrenia, as well as slightly less elevated levels in people with other mental disorders such as major depression, the team reports today in Neuron.
The famous cancer gene BRCA1 may also play a role in neurodevelopmental disorders such as microcephaly (right), which causes small brain size.
Unravelling this mechanism could also help scientists understand more about human cell dysfunctions linked to disorders such as diabetes, Parkinson's and other neurodegenerative diseases.
These studies raise the possibility that stress - related neuropsychiatric disorders such as PTSD may be more effectively treated with 5 - HT - targeted drugs in women and with AVP - targeted drugs in men.
«Our findings also suggest that defects in AIM2 may alter DNA sensing and thus contribute to intestinal inflammatory disorders such as IBD, ulcerative colitis, Crohn's disease, and colorectal cancer,» he said.
Why do people with sleep disorders such as insomnia often binge eat late at night?
In man, the dysfunction of the so - called HCN potassium channels is associated with neurological disorders such as epilepsy and depression.
The price of such rich diversity may be that mutations contributing to mental disorders such as schizophrenia sometimes emerge.
So far, DARPA has released two calls for grant applications, with at least one more likely: The first, called SUBNETS (Systems - Based Neurotechnology for Emerging Therapies), asks researchers to develop novel, wireless devices, such as deep brain stimulators, that can cure neurological disorders such as posttraumatic stress (PTS), major depression, and chronic pain.
«They might not arise from the same brain areas, but these observations are of importance in efforts to understand hallucinations that commonly occur in psychiatric disorders such as schizophrenia,» says Matcheri Keshavan, a psychiatrist at Harvard Medical School.
Short elements within a prion protein's sequence can cause it to activate and even cross the species barrier to spread neurodegenerative disorders such as Creutzfeldt - Jakob disease to humans
It developed synthetic sirtuin activating compounds (STACs) that are more powerful than resveratrol in the hope that they can treat age - related disorders such as type 2 diabetes and vascular disorders.
Poor sleep - quality is increasingly associated with the onset of various brain disorders such as Alzheimer's and Parkinson's disease.
«Dysfunction of mitochondria outer membrane proteins are linked to disorders such as diabetes, Parkinsons and other neurodegenerative diseases, so we hope that this work may also help us to better understand these human diseases too.»
Although Gage and colleagues have found that increased L1 is associated with mental disorders such as Rett syndrome, a form of autism, and a neurological motor disease called Louis - Bar syndrome, «no one had looked very carefully» to see if the gene might also contribute to schizophrenia, he says.
In addition to supercharging stamina, the drug, called AICAR, may also be useful in treating debilitating muscular disorders such as muscular dystrophy as well as metabolic diseases such as diabetes, because it also appears to help the body use and remove sugar from the blood more effectively.
Prions, the infectious agents best known for causing degenerative brain disorders such as «mad cow» disease, may have been spotted in bacteria.
For now, the findings apply only to mice, which are an imperfect model for complex cognitive disorders such as autism.
Woo and Ledley predict that clinical trials using gene therapy for metabolic disorders such as PKU could start within eight years.
Currently available genetic screening already lets parents know about such genetic disorders such as Down's syndrome or Tay - Sachs disease.
In a study published online April 28, 2014 in Nature, the researchers report that malfunctioning astrocytes might contribute to neurodegenerative disorders such as Lou Gehrig's disease (ALS), and perhaps even to developmental disorders such as autism and schizophrenia.
He and other supporters argued unsuccessfully that the move would pave the way to cures for conditions such as spinal cord injuries and sickle - cell anemia as well as degenerative disorders such as multiple sclerosis and Parkinson's and Alzheimer's diseases.
The same unknowns hold true for how genetic variation contributes to disorders such as schizophrenia and Parkinson's disease.
Scientists at the Stowers Institute for Medical Research have made a surprising finding about the aggregates of misfolded cellular proteins that have been linked to aging - related disorders such as Parkinson's disease.
In hereditary blood disorders such as sickle cell anaemia, the production of faulty cells leaves the patient extremely weak and anaemic.
Taking into account that the study was conducted with animals which aged naturally, we believe this could have the therapeutic ability to treat dementia and neurodegenerative disorders such as Alzheimer's or multiple sclerosis, among others,» Miguel Chillón points out.
In the past, Ghanei says, mustard victims with chronic symptoms were given standard treatments for chronic pulmonary disorders such as asthma: corticosteroids to tamp down inflammation and β2 - agonists for smooth muscle relaxation.
Prenatal whole - genome sequencing will provide volumes of information beyond the currently available tests for genetic disorders such as Down's syndrome or Tay - Sachs disease — assays that parents now use to decide how to respond to a pregnancy.
The report extends previous findings that showed that there is some shared genetic overlap between PTSD and other mental disorders such as schizophrenia.
Disruptions in stability cause disorders such as epilepsy, but precious little is known about this macro-level regulatory phenomenon.
The Behavioral Epigenetics conference, hosted by the New York Academy of Sciences and the University of Massachusetts Boston, is one of the first to examine how epigenetic changes take place, how they alter behavior, and how they can trigger the onset of disorders such as schizophrenia and depression.
Dysfunction of synapses is associated with a host of neuropsychiatric disorders such as epilepsy, addiction, schizophrenia and autism.
This technique has been shown to improve symptoms in people with brain disorders such as autism and depression.
Behavioural disorders such as those seen by the researchers are characterized by aggressive or antisocial behaviour, high activity levels, and difficulty inhibiting behaviour.
If the new mechanism also operates in the human brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing neurons which have died, thus restoring function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.
Lead author Cristina Dye, Lecturer in child language development at Newcastle University, says «Research examining children with disorders such as Tourette syndrome usually explore difficulties or weaknesses.
«Previously, genome - wide screens were only possible in lower animals, such as flies, worms and yeast, where it is often difficult to assess the relevance to human disorders such as cancer.»
This knowledge could help develop new therapies for psychiatric disorders such as schizophrenia or depression.
The clinics operate openly, with websites promoting the treatments for serious disorders such as Parkinson's disease, diabetes and autism, and attract thousands of medical tourists from overseas.
They are also interested in exploring the potential role of these cells in models of neurodegenerative movement disorders such as amyloid lateral sclerosis.
They found that for tranquillisers — including sleeping pills and drugs for treating anxiety and disorders such as schizophrenia — French doctors prescribe about four times as many DDDs per thousand people as their British and German counterparts, and two and a half times what doctors prescribed in Italy (see Graph).
It may help elucidate the defective processing behind mysterious disorders such as synesthesia, in which patients taste colors and see flavors.
The UAB researchers are currently interested in collaborating with other laboratories and obtaining funding to continue the studies of Ppm1f associated with other disorders such as cardiovascular diseases and cancer in order to verify whether their results are comparable in other diseases and potentially prevent them.
Along with his colleagues, Shaqfeh has now created the first simplified computer model of the process that forms that layer — a model that could help to improve the design of artificial platelets and medical treatments for trauma injuries and for blood disorders such as sickle cell anemia and malaria.
He said hypertensive disorders such as high blood pressure and pre-eclampsia were common complications for pregnant women and led to an increased risk of chronic high blood pressure in later life.
«The findings potentially have implications for social interactions in the workplace as well as clinical disorders such as depression.»
The defect in the responsible mouse gene — called klotho, after the goddess in Greek mythology who spins the thread of life — accelerates the onset of disorders such as atherosclerosis and osteoporosis.
Although previous research has identified genes involved with behaviors seen in eating disorders such as anorexia or bulimia, little is known about how natural variation in these genes could affect eating behaviors in healthy people.
«Many psychological disorders such as addiction, obesity, and depression involve poor regulation of reward circuitry.
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