Sentences with phrase «disrupt cell interactions»

However, because the membrane itself is often made of plastic, it can disrupt cell interactions and skew the results.

Not exact matches

When combined, these agents cause interactions that significantly disrupt cancer cells» ability to survive DNA damage, according to a preclinical study published in the journal Cancer Cell.

In preclinical experiments, the researchers disrupted AEG - 1 / Akt2 interaction through a process known as competitive binding and observed a reduction in GBM cell survival and invasion.

When the interaction of the cells within the cerebellum is disrupted, people experience fundamental disturbances in their motor function, making these simple actions difficult, or even impossible.

They have built proteins that disrupt other protein interactions in cells, including the interactions that prevent cancer cells from dying.

Alcohol reversibly disrupts TNF - α / TACE interactions in the cell membrane.

Conclusions: In an analysis of peripheral blood mononuclear cells and intestinal tissues from patients with inflammatory bowel diseases vs controls, we found that reactivity to intestinal bacteria is a normal property of the human CD4 + T - cell repertoire, and does not necessarily indicate disrupted interactions between immune cells and the commensal microbiota.

Helicobacter pylori VacA disrupts apical membrane - cytoskeletal interactions in gastric parietal cells.

Identifying and exploiting a novel mechanism that may disrupt this process by inhibiting the interactions between tumor cells and cells in the tumor environment will speed clinical investigations, and ultimately lead to improved outcomes for dogs with this devastating disease.

We propose that disrupting the interactions between hemangiosarcoma cancer stem cells and their microenvironment will enhance the sensitivity of these cells to conventional and targeted therapies and improve the outcomes of dogs with this disease.