Sentences with phrase «disrupt dystrophin»

Muscular dystrophy in dogs is caused by an inherited mutated dystrophin gene that disrupts the dystrophin protein production, resulting in loss of muscle function.

Not exact matches

This balance can be disrupted in diseases such as Duchenne muscular dystrophy, which is caused by the lack of a muscle - specific protein, dystrophin.

This approach has proved successful in disrupting multiple genes simultaneously in neurons and in editing the Dmdmdx mutation in muscle, thereby restoring dystrophin protein expression and partially alleviating the dystrophic muscles» functional deficiencies.