Sentences with phrase «disrupt key signaling»
But Lonard and O'Malley had a counterintuitive idea: what if they could disrupt key signaling pathways and kill cancer cells by overstimulating SRCs?
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«This study defines a signaling axis that is essential for head and neck cancer progression, and our findings show that this axis may be disrupted at three key steps,» says principal investigator Quintin Pan, PhD, associate professor of otolaryngology at the OSUCCC — James.
Due to reduced mTOR activity, a key intracellular signaling pathway regulator, the function of the cell's power plants, the mitochondria, is disrupted.