Not exact matches
Plakoglobin is a component of two important structures involved in cell - to - cell adhesion, and the investigators found that suppressing its expression caused CTC clusters to fall apart, reducing their metastatic potential, and also
disrupted cell - to - cell contact between
breast cancer cells but not
normal breast tissue.
Exposures to chemicals that
disrupt these
normal processes can alter
normal breast development in ways that lead to increased risk of
breast cancer in later life.
Since then, endocrine -
disrupting chemicals have been implicated in the dramatic rise over the last fifty years of diseases like
breast cancer, prostate cancer, testicular cancer, diabetes, obesity, decreased fertility, such as dropping
normal sperm counts.