The combination was significantly toxic to pancreatic cancer cells and
disrupted tumor growth and extended survival in several types of advanced pancreatic cancer mouse models.
Not exact matches
For example, if scientists can find a way to turn down overexpression of these genes in cancer, we could
disrupt cancer
growth and prevent
tumor progression.
In studies of laboratory - grown human
tumor cell lines, the drug
disrupted tumor cell division and prevented
growth of advanced cancer cells.
The study showed that the
tumor cells only contain one cilium and have
disrupted Sonic Hedgehog signaling, which drives
tumor - cell
growth.
Several anti-cancer drugs attempt to halt the
growth of
tumors by blocking mTOR, a key part of a
growth - regulating network that is often
disrupted in cancer cells.
Anti-angiogenic inhibitors slow down cancer
growth by
disrupting the blood supply to the
tumor.
In mouse models of cancer, targeted therapeutic inhibition of translation
disrupts this survival response, dramatically slowing
tumor growth and potentially rendering drug - resistant
tumors vulnerable to other therapies.
Dr. Evans has hypothesized that restoration of the quiescent PSC phenotype will
disrupt PSC —
tumor cell communication and impair
tumor growth.
Excitingly, we have shown in mouse models that
disrupting Yap1 blocks
tumor growth,» he says.
August 5, 2002 Gene therapy boosts cancer chemotherapy University of Chicago researchers have found a way to use cancer chemotherapy to turn on gene therapy designed to
disrupt the
growth of blood vessels to a
tumor.