If the molecules are pulled into an immune function in the fetus, she says, it could
disrupt brain development and lead to neurodevelopmental disorders.
While the study did not look for a mechanism, the team suggest that bilirubin, the toxin that accumulates in jaundice, may damage brain tissue and
disrupt brain development, leading to autism.
Fall - related injuries can
disrupt the brain development of children, and upset the delicate brain systems among the elderly,» said senior author Chris Dulla, Ph.D..
The authors point out that as nicotine may
disrupt brain development in humans, so neonicotinoids «may adversely affect human health, especially the developing brain».
These findings may correlate with
disrupted brain development, but direct evidence for a link between Zika virus and microcephaly is more likely to come from clinical studies, the researchers say.
«New studies point to autism beginning in the womb,» said Courchesne, who, with colleagues, published one such widely reported study last year detailing
disrupted brain development in post-mortem brains of autistic children.
One of the major reasons the study is so alarming is because abuse and neglect at an early age can
disrupt brain development and lead to a number of set - backs later in life.
Not exact matches
On a cognitive level, growing up in a chaotic and unstable environment — and experiencing the chronic elevated stress that such an environment produces —
disrupts the
development of a set of skills, controlled by the prefrontal cortex, known as executive functions: higher - order mental abilities that some researchers compare to a team of air - traffic controllers overseeing the working of the
brain.
Snoring
disrupts a child's sleep, which then
disrupts his natural
brain development and overall well - being.
Last week, the National Toxicology Program of the Health and Human Services Department found there was some concern the chemical could
disrupt development of the prostate gland and
brain, and cause behavioral problems for infants and children.
Recently, researchers from Harvard and Mt Sinai found that both environmental chemicals and environmental stress can
disrupt the
development of a fetus»
brain and negatively impact the baby's long - term health, even increasing the risk of autism spectrum disorders.
For example, knowing the precise
brain activity involved could shed light on disorders in which body awareness is
disrupted, such as schizophrenia, and help with the
development of prosthetic limbs that are more easily incorporated into body image.
Studies suggest that for many these compounds, low - level exposures in the womb seem to
disrupt development of the
brain or reproductive systems.
Genetics and the vagaries of
brain development disrupted these networks in dyscalculics, Butterworth proposed.
The findings suggest that damage to
brain cells called interneurons
disrupts neurotransmitter levels and plays a role in the
development of epilepsy after a traumatic
brain injury.
Current research addresses how
disrupted endocannabinoid signaling during
brain development primes for delayed neuropsychiatric illness.
Exposures of pregnant women and children to common thyroid - hormone -
disrupting toxins may be linked to the increased incidence of
brain development disorders, according to a review published in Endocrine Connections.
Though these findings have been obtained in mice, the scientists hypothesize that
disrupted coordination between the
development of the microglia and that of the
brain contributes to an increased risk of such neurodevelopmental disorders as autism and schizophrenia in human beings.
In this case, prenatal
brain development is initially normal, but then
disrupted by the viral infection of neural progenitors.
When the scientists exposed the
brains of pregnant mice to synthetic materials that mimic a CMV infection, they found that the
development of the pre-microglia was
disrupted in their offspring.
«By mapping the breakpoints, we were able to identify genes that were
disrupted in patients with birth defects, which suggests that these genes play a key role in normal
brain development,» she said.
BETHESDA, MD — Infection with Zika virus
disrupts fetal
brain development by interfering with the proliferation of human neural progenitor cells (hNPCs), a type of cell that drives neurodevelopment and proliferates into
brain and nervous system cells, according to research presented at the American Society of Human Genetics (ASHG) 2016 Annual Meeting in Vancouver, B.C.
Animals treated with MSG developed
brain lesions, caused stunted skeletal
development and weight gain, and
disrupted the neural centers responsible for hormone function [5].
The delicate balance between the human microbiome and the
development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or
disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered
brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of
brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.
Phthalates and other endocrine -
disrupting chemicals may perturb this hormonal balance and
disrupt fetal
brain development (Zoeller and Crofton 2000).
Research shows that excessive experience with toxic stress can
disrupt the
development of
brain circuits related to stress response — and to learning and memory.
Toxic stress
disrupts the
development of the areas of the
brain associated with learning and can have lifelong consequences.
Effectively, anything that
disrupts brain circuitry can affect the
development of epilepsy.
Poverty in early (preschool) childhood has been emphasised as especially detrimental to
development, 22 23 as this is a crucial time for
brain development and may
disrupt the many core cognitive and social competencies being acquired during this time.
«You can't be exposed to the research on
brain development and continue business as usual,» he said, warning that current paradigms of policy and services needed to be
disrupted.
It can
disrupt early
brain development and lead to many health problems.
When
brain development is held back by neglect or trauma, the way the
brain is affected during that time greatly
disrupts children's abilities to connect with others and causes a host of challenging behaviors.
The biology of early childhood adversity reveals the important role of toxic stress in
disrupting developing
brain architecture and adversely affecting the concurrent
development of other organ systems and regulatory functions.
Antenatal depression may not only alter
development of stress - related biological systems in the fetus, but may also increase risk of obstetrical complications.6 Postnatal depression may also be an early life stressor given known associations with lower levels of sensitive, responsive care needed for infants»
development of health attachment relationships, emotional regulation skills, interpersonal skills and stress response mechanisms.7 Early life stressors, such as those that might be associated with maternal depression, can influence
brain development, which continues at a rapid pace at least for several years after birth.8 Problems in any of these aspects of
development may
disrupt the earliest stages of socio - emotional and cognitive
development, predisposing to the later
development of depression or other disorders.
Toxic stress
disrupts healthy
brain development, which can lead to increase physical and mental illness, high - risk behaviors, and other psychosocial implications.
Brain development continues during these years and can be
disrupted by alcohol and drug use.