Sentences with phrase «distal gene enhancer»
Enhancer Element Locator, or EEL, is a tool for locating distal gene enhancer elements in mammalian genomes by comparative genomics.
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The researchers then inactivated a distal DNA enhancer element that contains instructions to transcribe Cryptochrome 1, which is a gene that produces a protein involved in maintaining the circadian rhythm itself.
The findings are reported in the article «A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential» published online December 15 in Genes & Development.
Chromatin interactions, trans - regulatory events, and distal enhancers are just some of the mechanisms by which elements in the genome can modulate distant genes.