Sentences with phrase «distinct cell lineages»

Not exact matches

The research team found that two distinct B - cell lineage antibodies teamed up to stimulate the highly sought - after broadly neutralizing antibodies to HIV.

By March 2014 — about the time the epidemic was detected, but some 3 months after the first case actually occurred — the sequences had split into two distinct lineages, one of which was characterized by a single amino acid change in a region of the virus's surface protein and allows it to bind to cells.

So confused is the genetic history of llamas that some are in fact chimeras; they have cells in their bodies from two distinct maternal lineages.

These findings suggested that exhausted T cells are a distinct lineage of T cells in and of themselves instead of just being effector or memory T cells restrained by checkpoint pathways.

Recently, several observations suggested that, besides monocyte - derived macrophages, dendritic cells, a distinct myeloid lineage, also express PPARγ at high levels.

Resident macrophages from the same lineage, such as liver Kupffer cells, brain microglia, epidermal Langerhans cells, lung alveolar macrophages..., display tissue - specific phenotypes, perform tissue - specific functions and have distinct gene expression profiles.

Differential expression of surface markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment.

Lineage - restricted progenitors are identifiable by expression of distinct combinations of cell surface markers.

The existence of multiple sub-states within a single ES cell basin of attraction or multiple interrelated attractors representing distinct lineages could account for pluripotency.

While the small changes in lineage transcription observed in our data set would be consistent with a stochastic model, the ES cell model described in Figure 9 would require both cross-repression and additional positive feedback loops to drive these random changes in gene expression down multiple distinct routes.

CpG stimulation of precursor B lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells towards a Th1 response.

Concomitantly, epiblast cells transit through distinct pluripotent states, before lineage commitment at gastrulation.

The epidermis is maintained by multiple stem cell populations whose progeny differentiate along diverse, and spatially distinct, lineages.