Not exact matches
«What David's group can do is grow populations of
cells in a very miniaturized
state in ways that they can reach out and talk to each other through tiny channels, but yet they stay
distinct,» den Boon says.
Their findings outlined four
distinct cellular phases of sperm stem
cells maturation, revealing how the stem
cells progress from a «quiescent»
state, to a «proliferation»
state during which stem
cells divide, to a final «differentiation»
state when stem
cells mature to become sperm.
«Our research shows that the protein GSK3 plays a crucial role in helping B
cells meet the energy needs of their
distinct states,» says Robert Rickert, Ph.D., director of the Tumor Microenvironment and Cancer Immunology Program at Sanford Burnham Prebys Medical Discovery Institute (SBP).
Specifically, the data reveal
distinct transitions in factors that influence the different cellular
states including
cell cycle regulators, transcription factors, and signaling factors.
It will further discuss efforts to capture
distinct stem
cell types and
states from the preimplantation embryo including naïve human embryonic stem
cells.
Simon's favorite approach is to examine the context of the
cell - properties that make
distinct cell types unique in their normal and cancerous
states.
Her current research is focused on discovering how normal and disease melanocyte
cell states establish
distinct regulatory DNA landscapes, and also determining how the combination of both genetic variation within these regulatory regions and environmental
cell signals alter gene expression and normal
cell function.
Concomitantly, epiblast
cells transit through
distinct pluripotent
states, before lineage commitment at gastrulation.
Even more
distinct is the specific project that students in the program are involved in: They work with the
state's transportation engineers and top auto designers on the next generation of fuel
cell vehicles, benefiting from resources and advice from the California Fuel Cell Partners
cell vehicles, benefiting from resources and advice from the California Fuel
Cell Partners
Cell Partnership.