Sentences with phrase «distinct gene promoters»

In total, 448 distinct gene promoters were differentially methylated in CPA.

Not exact matches

Using bioinformatics tools to identify and map out specific components and regulatory interconnections, the study team found highly dynamic activities during CD8 + T cell responses: a distinct repertoire of super enhancers — groups of enhancers that interact with promoters to drive gene transcription, new groups of enhancers that jump into activity only in the memory cell stage, and extensive re-wiring of regulatory circuits from one cell stage to another.

In two different experiments, Fukaya placed the enhancer either upstream of the gene's promoter, or downstream of the gene and saw that the different enhancer positions resulted in distinct responses.