Not exact matches
These studies have given us a better understanding
of the
genes that influence the development
of these cells, and in particular, to characterize the differences between
subsets of Vα14i NKT cells with
distinct functional properties.
As all
of these Oct4 homodimer and heterodimer conformations bind
distinct DNA motifs, a signaling - based mechanism could potentially control the transcription
of distinct subsets of Oct4 target
genes.
There it correlates with
gene repression, but likely only in
distinct subsets of cells within each organ, (see Schultz et al., 2015).